Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Héloïse Carion"'
Autor:
Yolanda Y. Huang, Morgan N. Price, Allison Hung, Omree Gal-Oz, Surya Tripathi, Christopher W. Smith, Davian Ho, Héloïse Carion, Adam M. Deutschbauer, Adam P. Arkin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract A mechanistic understanding of host-microbe interactions in the gut microbiome is hindered by poorly annotated bacterial genomes. While functional genomics can generate large gene-to-phenotype datasets to accelerate functional discovery, the
Externí odkaz:
https://doaj.org/article/6c26e2bd51264f1ca4e44d71b211f4aa
Autor:
Sukrit Silas, Héloïse Carion, Kira S. Makarova, Eric Laderman, David Sanchez Godinez, Matthew Johnson, Andrea Fossati, Danielle Swaney, Michael Bocek, Eugene V. Koonin, Joseph Bondy-Denomy
Genomes of bacterial and archaeal viruses are replete with fast-evolving, uncharacterized accessory genes (AGs), most of which likely antagonize host defenses or other viruses. We developed a computational pipeline to find AGs in bacteriophage genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::190fb1a2d447029affa296a51b311d59
https://doi.org/10.1101/2023.04.06.535777
https://doi.org/10.1101/2023.04.06.535777
Autor:
Nicole D. Marino, Alexander Talaie, Héloïse Carion, Yang Zhang, Sukrit Silas, Yuping Li, Joseph Bondy-Denomy
Bacterial CRISPR-Cas systems cleave the genomic DNA of bacteriophage and other mobile genetic elements. Many temperate phages encode anti-CRISPR (Acr) proteins that use diverse and innovative mechanisms to inhibit CRISPR-Cas and stabilize lysogeny. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec3feefe30a61e50e3f43a954338584
https://doi.org/10.1101/2022.11.29.518452
https://doi.org/10.1101/2022.11.29.518452
Autor:
Yolanda Y. Huang, Morgan N. Price, Allison Hung, Omree Gal-Oz, Davian Ho, Héloïse Carion, Adam M. Deutschbauer, Adam P. Arkin
A mechanistic understanding of host-microbe interactions in the gut microbiome is hindered by poorly annotated bacterial genomes. While functional genomics can generate large gene-to-phenotype datasets to accelerate gene discovery, their applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788ac27b76c94d59561629526d58d2ed
https://doi.org/10.1101/2022.10.10.511384
https://doi.org/10.1101/2022.10.10.511384
Autor:
Erin Huiting, Xueli Cao, Jie Ren, Januka S. Athukoralage, Zhaorong Luo, Sukrit Silas, Na An, Héloïse Carion, Yu Zhou, James S. Fraser, Yue Feng, Joseph Bondy-Denomy
Publikováno v:
Cell. 186:864-876.e21
Autor:
Erin Huiting, Januka Athukoralage, Jingwen Guan, Sukrit Silas, Héloïse Carion, Joseph Bondy-Denomy
SummaryThe recently discovered cyclic-oligonucleotide-based anti-phage signaling system (CBASS) is related to eukaryotic cGAS-STING anti-viral immunity and is present in diverse prokaryotes. However, our understanding of how CBASS detects, inhibits,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86fb97befd8db0bbc1f425edd7b531c9
https://doi.org/10.1101/2022.03.30.486325
https://doi.org/10.1101/2022.03.30.486325