Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hélio Faustino"'
Autor:
Romina Coelho, Chiara A. De Benedictis, Ann Katrin Sauer, António J. Figueira, Hélio Faustino, Andreas M. Grabrucker, Cláudio M. Gomes
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1787 (2024)
Proteinaceous aggregates accumulate in neurodegenerative diseases such as Alzheimer’s Disease (AD), inducing cellular defense mechanisms and altering the redox status. S100 pro-inflammatory cytokines, particularly S100B, are activated during AD, bu
Externí odkaz:
https://doaj.org/article/bdfc9df2f35449849ff52ddffc1b849c
Publikováno v:
Foods, Vol 12, Iss 16, p 2994 (2023)
The European Union has established two designations, Protected Designation of Origin (PDO) and Protected Geographical Indication (PGI), to guarantee the authenticity of products with valued specificities associated with the regions where they are pro
Externí odkaz:
https://doaj.org/article/78137cf6b2254f80ac3abcffed51b636
Publikováno v:
Molecules, Vol 15, Iss 12, Pp 9308-9322 (2010)
The antioxidant activity of the phenolic compounds present in industrial black liquors obtained from the two cooking processes (kraft and sulphite) used in Portugal to produce Eucalyptus globulus pulp was evaluated. The black liquors treated at sever
Externí odkaz:
https://doaj.org/article/7443c42236ab418c8f590718289408e8
Autor:
Diogo L. Poeira, Ana Cláudia R. Negrão, Hélio Faustino, Jaime A. S. Coelho, Clara S. B. Gomes, Pedro M. P. Gois, M. Manuel B. Marques
Publikováno v:
Organic Letters. 24:776-781
A new family of hypervalent iodine reagents containing transferable primary amine groups is described. Benziodoxolone-based reagents were synthesized on the gram-scale through operationally simple reactions in up to quantitative yields. These bench-s
Autor:
João P. M. António, Joana Inês Carvalho, Ana S. André, Joana N. R. Dias, Sandra I. Aguiar, Hélio Faustino, Ricardo M. R. M. Lopes, Luis F. Veiros, Gonçalo J. L. Bernardes, Frederico A. Silva, Pedro M. P. Gois
Publikováno v:
Angewandte Chemie. 133:26118-26125
Autor:
Maria J. S. A. Silva, Rafaela A. N. Cavadas, Hélio Faustino, Luís F. Veiros, Pedro M. P. Gois
Publikováno v:
Chemistry – A European Journal. 28
Autor:
Maria J. S. A. Silva, Rafaela A. N. Cavadas, Hélio Faustino, Luís F. Veiros, Pedro M. P. Gois
Publikováno v:
Chemistry – A European Journal. 28
N-terminal Cys modification has been intensively studied to produce homogeneous bioconjugates essentially through two modes of reaction: reversible modification with the equilibrium shifted towards the formation of the desired conjugate or stable and
Autor:
Mariama Djaló, Maria J. S. A. Silva, Hélio Faustino, Sandra N. Pinto, Ricardo Mendonça, Pedro M. P. Gois
Publikováno v:
Chemical communications (Cambridge, England). 58(57)
The site-selective chemical appendage of multiple functionalities on a native peptide backbone is a highly demanding and complex tool of modern chemical biology. Here, novel NHS-activated acrylates were designed to hold various payloads in a single b
Publikováno v:
Organic & Biomolecular Chemistry. 19:6221-6226
In this work, we describe the preparation of a heterobifunctional 2-formylphenylboronic acid (2-FPBA)-maleimide crosslinker and explore its versatility in the preparation of various bioconjugates. We demonstrate the straightforward attachment of hydr
Autor:
Frederico Aires da Silva, Ana S. André, Joana N R Dias, Gonçalo J. L. Bernardes, João P. M. António, Joana Carvalho, Pedro M. P. Gois, Ricardo M R M Lopes, Luis F. Veiros, Hélio Faustino
Antibody-drug conjugates (ADCs) are a new class of therapeutics that combine the lethality of potent cytotoxic drugs with the targeting ability of antibodies to selectively deliver drugs to cancer cells. The synthesis of ADCs is challenging, and stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::331cc1b9987503b9e36aa7280e0a9fbf
https://doi.org/10.33774/chemrxiv-2021-qh8zd
https://doi.org/10.33774/chemrxiv-2021-qh8zd