Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution

Autor: Kasper Kjaer-Sorensen, Pia Jensen, Hélicia Claude, Carsten Weiss, Clemens Grabher, Yuya Hayashi, Thomas Boesen, Uwe Strähle, Claude Antony, Isaac Ojea-Jiménez, Masanari Takamiya, Douglas Gilliland, Claus Oxvig

Publikováno v: Hayashi, Y, Takamiya, M, Jensen, P B, Ojea-Jiménez, I, Claude, H, Antony, C, Kjaer-Sorensen, K, Grabher, C, Boesen, T, Gilliland, D, Oxvig, C, Strähle, U & Weiss, C 2020, ' Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized i n Vivo in Real-Time and at Ultrastructural Resolution ', ACS Nano, vol. 14, no. 2, pp. 1665-1681 . https://doi.org/10.1021/acsnano.9b07233

Despite the common knowledge that the reticuloendothelial system is largely responsible for blood clearance of systemically administered nanoparticles, the sequestration mechanism remains a "black box". Using transgenic zebrafish embryos with cell ty

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