Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hélène Vitet"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The synchronization of multiple oscillators serves as the central mechanism for maintaining stable circadian rhythms in physiology and behavior. Aging and disease can disrupt synchronization, leading to changes in the periodicity of circadian activit
Externí odkaz:
https://doaj.org/article/c816f6b9619743ea954e1dc73b2563d8
Autor:
Hélène Vitet, Julie Bruyère, Hao Xu, Claire Séris, Jacques Brocard, Yah-Sé Abada, Benoît Delatour, Chiara Scaramuzzino, Laurent Venance, Frédéric Saudou
Publikováno v:
eLife, Vol 12 (2023)
Neurotransmitters are released at synapses by synaptic vesicles (SVs), which originate from SV precursors (SVPs) that have traveled along the axon. Because each synapse maintains a pool of SVs, only a small fraction of which are released, it has been
Externí odkaz:
https://doaj.org/article/b69d94da556b44d79eb205d590d95d58
Autor:
Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105857- (2022)
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Externí odkaz:
https://doaj.org/article/fd15b7293989424cb83b9058a66155a8
Autor:
Laure Asselin, José Rivera Alvarez, Solveig Heide, Camille S. Bonnet, Peggy Tilly, Hélène Vitet, Chantal Weber, Carlos A. Bacino, Kristin Baranaño, Anna Chassevent, Amy Dameron, Laurence Faivre, Neil A. Hanchard, Sonal Mahida, Kirsty McWalter, Cyril Mignot, Caroline Nava, Agnès Rastetter, Haley Streff, Christel Thauvin-Robinet, Marjan M. Weiss, Gladys Zapata, Petra J. G. Zwijnenburg, Frédéric Saudou, Christel Depienne, Christelle Golzio, Delphine Héron, Juliette D. Godin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Kinesins regulate intracellular transport and microtubule dynamics. Here, the authors show that KIF21B variants in humans associate with corpus callosum agenesis and microcephaly. Using mice and zebrafish, they showed the cellular mechanisms altered
Externí odkaz:
https://doaj.org/article/85fa7763d73b4163bd09f2ee5a5c74a8
Autor:
Julie Bruyère, Yah-Se Abada, Hélène Vitet, Gaëlle Fontaine, Jean-Christophe Deloulme, Aurélia Cès, Eric Denarier, Karin Pernet-Gallay, Annie Andrieux, Sandrine Humbert, Marie-Claude Potier, Benoît Delatour, Frédéric Saudou
Publikováno v:
eLife, Vol 9 (2020)
Studies have suggested that amyloid precursor protein (APP) regulates synaptic homeostasis, but the evidence has not been consistent. In particular, signaling pathways controlling APP transport to the synapse in axons and dendrites remain to be ident
Externí odkaz:
https://doaj.org/article/b038de28dd5a440288feebeb14342e19
Autor:
Yann Ehinger, Julie Bruyère, Nicolas Panayotis, Yah‐Se Abada, Emilie Borloz, Valérie Matagne, Chiara Scaramuzzino, Hélène Vitet, Benoit Delatour, Lydia Saidi, Laurent Villard, Frédéric Saudou, Jean‐Christophe Roux
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
Abstract Mutations in the X‐linked MECP2 gene are responsible for Rett syndrome (RTT), a severe neurological disorder for which there is no treatment. Several studies have linked the loss of MeCP2 function to alterations of brain‐derived neurotro
Externí odkaz:
https://doaj.org/article/094d5708255640e8bd9f8ac0e89b5fea
Autor:
Hélène Vitet, Julie Bruyère, Hao Xu, Jacques Brocard, Yah Sé Abada, Benoît Delatour, Chiara Scaramuzzino, Laurent Venance, Frédéric Saudou
Neurotransmitters are released at synapses by synaptic vesicles (SVs), which originate from SV precursors (SVPs) that have traveled along the axon. Because each synapse maintains a pool of SVs, only a small fraction of which are released, it is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5843e263f544918886b0bc9be20d552
https://doi.org/10.1101/2022.08.14.503885
https://doi.org/10.1101/2022.08.14.503885
Autor:
Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v:
Neurobiology of disease. 173
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Autor:
Petra J. G. Zwijnenburg, Kirsty McWalter, Sonal Mahida, Delphine Héron, Frédéric Saudou, Hélène Vitet, Anna Chassevent, José Rivera Alvarez, Carlos A. Bacino, Juliette D. Godin, Christel Thauvin-Robinet, Chantal Weber, Laure Asselin, Caroline Nava, Christelle Golzio, Neil A. Hanchard, Christel Depienne, Peggy Tilly, Camille S. Bonnet, Cyril Mignot, Gladys Zapata, Amy Dameron, Marjan M. Weiss, Solveig Heide, Laurence Faivre, Haley Streff, Agnès Rastetter, Kristin W. Barañano
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-16294-6⟩
Nature Communications, 11, 1, pp. 1-18
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, 11, 1-18
Asselin, L, Rivera Alvarez, J, Heide, S, Bonnet, C S, Tilly, P, Vitet, H, Weber, C, Bacino, C A, Baranaño, K, Chassevent, A, Dameron, A, Faivre, L, Hanchard, N A, Mahida, S, McWalter, K, Mignot, C, Nava, C, Rastetter, A, Streff, H, Thauvin-Robinet, C, Weiss, M M, Zapata, G, Zwijnenburg, P J G, Saudou, F, Depienne, C, Golzio, C, Héron, D & Godin, J D 2020, ' Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity ', Nature Communications, vol. 11, no. 1, 2441 . https://doi.org/10.1038/s41467-020-16294-6
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-16294-6⟩
Nature Communications, 11, 1, pp. 1-18
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, 11, 1-18
Asselin, L, Rivera Alvarez, J, Heide, S, Bonnet, C S, Tilly, P, Vitet, H, Weber, C, Bacino, C A, Baranaño, K, Chassevent, A, Dameron, A, Faivre, L, Hanchard, N A, Mahida, S, McWalter, K, Mignot, C, Nava, C, Rastetter, A, Streff, H, Thauvin-Robinet, C, Weiss, M M, Zapata, G, Zwijnenburg, P J G, Saudou, F, Depienne, C, Golzio, C, Héron, D & Godin, J D 2020, ' Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity ', Nature Communications, vol. 11, no. 1, 2441 . https://doi.org/10.1038/s41467-020-16294-6
KIF21B is a kinesin protein that promotes intracellular transport and controls microtubule dynamics. We report three missense variants and one duplication in KIF21B in individuals with neurodevelopmental disorders associated with brain malformations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2280cfa8349226d6a47d71980798ba85
https://hal.archives-ouvertes.fr/hal-03373809
https://hal.archives-ouvertes.fr/hal-03373809
Autor:
Benoît Delatour, Jean-Christophe Deloulme, Frédéric Saudou, Yah-Se Abada, Julie Bruyère, Aurélia Cès, Karin Pernet-Gallay, Eric Denarier, Sandrine Humbert, Annie Andrieux, Hélène Vitet, Gaëlle Fontaine, Marie-Claude Potier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b9d410d61b094ca5877f4034eed89a
https://doi.org/10.7554/elife.56371.sa2
https://doi.org/10.7554/elife.56371.sa2