A Nonsteroidal Novel Formulation Targeting Inflammatory and Pruritus-Related Mediators Modulates Experimental Allergic Contact Dermatitis

Autor: Nicolas G. Bazan, Bokkyoo Jun, David Rodríguez Gil, Gabriela Silvina Bacchini, William C. Gordon, Fernando Pineda De La Losa, Ricardo Palacios Pelaez, Hélène Varoqui, Virginia García López, Javier Alcover Díaz, Surjyadipta Bhattacharjee, Concha Tiana Ferrer

Publikováno v: Dermatology and Therapy

Introduction A major clinical challenge in treating allergic contact dermatitis (ACD) is that the first line of treatment is based on the use of corticosteroids. In this study, we aimed to develop a formulation that is devoid of steroids. Methods We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfcd1e493be0d211e41f030073a1f564
https://pubmed.ncbi.nlm.nih.gov/29453524

Identification of Endophilins 1 and 3 as Selective Binding Partners for VGLUT1 and Their Co-Localization in Neocortical Glutamatergic Synapses: Implications for Vesicular Glutamate Transporter Trafficking and Excitatory Vesicle Formation

Autor: Sukhjeevan Grewal, Marie E. K. Morris, Hélène Varoqui, Stéphanie De Gois, Elisabeth M. Jeanclos, Jeffrey D. Erickson

Publikováno v: Cellular and Molecular Neurobiology. 26:677-691

1. Selective protein-protein interactions between neurotransmitter transporters and their synaptic targets play important roles in regulating chemical neurotransmission. We screened a yeast two-hybrid library with bait containing the C-terminal amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a575327efaaa9f2d7fbde700d1b607f2
https://doi.org/10.1007/s10571-006-9054-8

Localization of the Na+-coupled neutral amino acid transporter 2 in the cerebral cortex

Autor: Jeffrey D. Erickson, Fiorenzo Conti, Hélène Varoqui, Marcello Melone

Publikováno v: Neuroscience. 140:281-292

We studied the distribution and cellular localization of Na + -coupled neutral amino acid transporter 2, a member of the system A family of amino acid transporters, in the rat and human cerebral cortex using immunocytochemical methods. Na + -coupled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1b677dce1164a28305acb9123599a4
https://doi.org/10.1016/j.neuroscience.2006.02.042

The synthesis of SNAT2 transporters is required for the hypertonic stimulation of system A transport activity

Autor: Renata Franchi-Gazzola, Hélène Varoqui, Ovidio Bussolati, Rossana Visigalli, Roberto Sala, Valeria Dall'Asta, Jeffrey D. Erickson, Elena Bevilacqua, Francesca Gaccioli, Gian C. Gazzola

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1667(2):157-166

In cultured human fibroblasts incubated under hypertonic conditions, the stimulation of system A for neutral amino acid transport, associated to the increased expression of the mRNA for SNAT2 transporter, leads to an expanded intracellular amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e71c8492d9f1b69115eee464682189

Coregulation of Two Embedded Gene Products, Choline Acetyltransferase and the Vesicular Acetylcholine Transporter

Autor: Maurice Israël, Jacques Mallet, Riccardo Cervini, Marie-Françoise Diebler, Sylvie Berrard, Hélène Varoqui

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, Wiley, 1995, 65 (2), pp.939-942. ⟨10.1046/j.1471-4159.1995.65020939.x⟩
Journal of Neurochemistry, 1995, 65 (2), pp.939-942. ⟨10.1046/j.1471-4159.1995.65020939.x⟩

International audience; The gene encoding the vesicular acetylcholine transporter (VAChT) has recently been localized within the first intron of the gene encoding choline acetyltransferase (ChAT) and is in the same transcriptional orientation. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18323184d39f519abceded352eb66931
https://doi.org/10.1046/j.1471-4159.1995.65020939.x