Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hélène Van Melckebeke"'
Autor:
Anja Böckmann, Christian Wasmer, Paul Schanda, Beat H. Meier, Adam Lange, René Verel, Julia Gath, Hélène Van Melckebeke
Publikováno v:
Journal of Molecular Biology. 405:765-772
Despite the importance of protein fibrils in the context of conformational diseases, information on their structure is still sparse. Hydrogen/deuterium exchange measurements of backbone amide protons allow the identification hydrogen-bonding patterns
Autor:
Adam Lange, Beat H. Meier, Wilfred F. van Gunsteren, Hélène Van Melckebeke, Alice Soragni, Zrinka Gattin, Christian Wasmer
Publikováno v:
ChemBioChem. 10:1657-1665
The three-dimensional structure of amyloid fibrils of the prion-forming part of the HET-s protein [HET-s(218-289)], as determined by solid-state NMR, contains rigid and remarkably well-ordered parts, as witnessed by the narrow solid-state NMR line wi
Autor:
Jérôme Boisbouvier, David L. Bryce, Carmelo Di Primo, Jean-Jacques Toulmé, Hélène Van Melckebeke, François Beaurain, Matthew Devany
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9210-9215
Transactivation-response element (TAR) is a stable stem–loop structure of HIV RNA, which plays a crucial role during the life cycle of the virus. The apical loop of TAR acts as a binding site for essential cellular cofactors required for the replic
Autor:
Adam Lange, Beat H. Meier, Hélène Van Melckebeke, Roland Riek, Ansgar B. Siemer, Christian Wasmer
Publikováno v:
Science. 319:1523-1526
Prion and nonprion forms of proteins are believed to differ solely in their three-dimensional structure, which is therefore of paramount importance for the prion function. However, no atomic-resolution structure of the fibrillar state that is likely
Autor:
Ana Amoroso, Julien Boudet, Jean-Pierre Simorre, Valérie Duval, Hélène Van Melckebeke, Martin Blackledge, Bernard Joris
Publikováno v:
Nucleic Acids Research
In absence of beta-lactam antibiotics, BlaI and MecI homodimeric repressors negatively control the expression of genes involved in beta-lactam resistance in Bacillus licheniformis and in Staphylococcus aureus. Subsequently to beta-lactam presence, Bl
Autor:
Arthur Pardi, Bernhard Brutscher, Hélène Van Melckebeke, Jérôme Boisbouvier, Jean-Pierre Simorre
Publikováno v:
Journal of Biomolecular NMR. 32:263-271
New base-type-edited transverse-relaxation optimized CT-HCN(C) experiments are presented that yield intra-base and sugar-to-base correlations for 13C-15N labeled RNA. High spectral resolution in the 13C and 15N dimensions is achieved by constant time
Autor:
Ansgar B. Siemer, Stephanie G. Köneke, Matthias Ernst, Hélène Van Melckebeke, Michel O. Steinmetz, Christian Wasmer, Beat H. Meier, Adam Lange, René Verel
Publikováno v:
ResearcherID
Publikováno v:
Journal of the American Chemical Society. 126(31)
New NMR experiments are presented for the measurement of methyl-methyl distances in (13)C-labeled proteins from a series of amino acid-type separated 2D or 3D NOESY spectra. Hadamard amino acid-type encoding of the proximal methyl groups provides the
Publikováno v:
Journal of magnetic resonance (San Diego, Calif. : 1997). 170(2)
A detailed theoretical and experimental analysis of the artifacts induced by homonuclear band-selective decoupling during CT frequency labeling is presented. The effects are discussed in the context of an amino-acid-type editing filter implemented in
Autor:
Tony Aerts, Bernard Joris, Gabriel Llabres, Hélène Van Melckebeke, André Matagne, Patrice Filée, Peter Paul De Deyn, Jean-Pierre Simorre, Christelle Vreuls, Jean-Marie Frère
Publikováno v:
The biochemical journal
The Bacillus licheniformis 749/I BlaI repressor is a prokaryotic regulator that, in the absence of a β-lactam antibiotic, prevents the transcription of the blaP gene, which encodes the BlaP β-lactamase. The BlaI repressor is composed of two structu