Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hélène Maurice"'
Publikováno v:
British Journal of Pharmacology. 130:1777-1784
Serum from humans with an acute upper respiratory viral infection and from rabbits with turpentine-induced inflammation reduce the catalytic activity of hepatic cytochrome P450 (P450). The aim of this study was to identify the serum mediators respons
Autor:
P. du Souich, S. Dalkara, Hélène Maurice, Ayman O. S. El-Kadi, J Kurdi, Huy Ong, P M Bélanger
Publikováno v:
British Journal of Pharmacology. 128:365-373
To investigate the effect of moderate hypoxia alone or combined with an inflammatory reaction or after 3-methylcholanthrene (3MC) pre-treatment on cytochrome P450 (P450), conscious rabbits were exposed for 24 h to a fractional concentration of inspir
Publikováno v:
British Journal of Pharmacology. 121:1164-1170
1. Infection and inflammation trigger a cascade of mediators that eventually will down-regulate the hepatic cytochrome P450 (P450). The present study aimed to characterize the mediators contained in the serum of rabbits with an acute inflammatory rea
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 23:567-580
In humans, oral bioavailability of nifedipine has been reported to be around 60%, although the organ(s) contributing to its first-pass metabolism have not been determined. The aim of this study was to determine in vivo, in anesthetized and conscious
Publikováno v:
British Journal of Pharmacology. 116:2407-2412
1. Frusemide is removed from the body by biotransformation and renal secretion, but since frusemide metabolism is not altered in patients with hepatic cirrhosis, the role of the liver may be questioned. The aim of the study was to investigate which o
Autor:
F. Lapicque, Alain Nicolas, Pierre Leroy, Marie-Hélène Maurice, Zaïd Abdelhamid, Jacques Magdalou, Saïd Chakir, Nathalie Dubois
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 654:61-68
A stereoselective high-performance liquid chromatographic (HPLC) method was developed to study the in vitro glucuronidation of ketoprofen enantiomers by liver microsomes. The HPLC system consisted of a Superspher 100 RP 18 end-capped column eluted wi