Three-dimensional characterization of the vascular bed in bone metastasis of the rat by microcomputed tomography (MicroCT).

Autor: Hervé Nyangoga, Philippe Mercier, Hélène Libouban, Michel Félix Baslé, Daniel Chappard

Publikováno v: PLoS ONE, Vol 6, Iss 3, p e17336 (2011)

BACKGROUND: Angiogenesis contributes to proliferation and metastatic dissemination of cancer cells. Anatomy of blood vessels in tumors has been characterized with 2D techniques (histology or angiography). They are not fully representative of the traj

Externí odkaz: https://doaj.org/article/3be924fe725c4264a618adde8905c287

Data from Pharmacologic inhibitors of IκB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo

Autor: Stuart H. Ralston, Daniel Chappard, Euphemie Landao-Bassonga, Hervé Nyangoga, Hélène Libouban, Aymen I. Idris

The NF-κB signaling pathway is known to play an important role in the regulation of osteoclastic bone resorption and cancer cell growth. Previous studies have shown that genetic inactivation of IκB kinase (IKK), a key component of NF-κB signaling,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f9c5beb02f5ff18eae5a6c1f9a9024
https://doi.org/10.1158/1535-7163.c.6531878

In vivo osseointegration and erosion of nacre screws in an animal model

Autor: Hélène Libouban, Jean-Daniel Kün-Darbois, Serge Camprasse, Daniel Chappard, Georges Camprasse

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Wiley, 2020, ⟨10.1002/jbm.b.34743⟩

International audience; The use of resorbable devices for osteosynthesis has become a subject of interest. Nacre has been proposed as a resorbable and osteoconductive material favoring bone apposition without triggering an inflammatory reaction. We c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7916307e125b7eebeadd2e9c6213fb93
https://doi.org/10.1002/jbm.b.34743

Human macrophages and osteoclasts resorb β-tricalcium phosphate in vitro but not mouse macrophages

Autor: Guillaume Mabilleau, Daniel Chappard, Baptiste Arbez, Florence Manero, Hélène Libouban

Publikováno v: Micron (Oxford, England : 1993)
Micron (Oxford, England : 1993), 2019, 125, pp.102730. ⟨10.1016/j.micron.2019.102730⟩

International audience; β-TCP is a resorbable bony biomaterial but its biodegradation mechanisms in vivo remains unclear. Osteoclast can resorb β-TCP but a role for macrophages has also been suggested by in vivo studies. However no in vitro study h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72907433af2369c3956e4ecc0ff4fc0e
https://hal.univ-angers.fr/hal-02869318

Érosion in vivo de vis orthopédiques préparées à partir de la nacre d’huître perlière

Autor: G. Camprasse, Hélène Libouban, S. Camprasse, Florence Pascaretti-Grizon, Daniel Chappard

Publikováno v: Revue de Chirurgie Orthopédique et Traumatologique. 102:657-662

Resume Introduction Des biomateriaux biodegradables ont ete proposes pour preparer des dispositifs orthopediques. La nacre est un materiau naturel bioerodable a base d’aragonite (carbonate de calcium). Hypothese Nous postulons que la nacre est biod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::022e908fbec3fa7de1976d69eae2fa7e
https://doi.org/10.1016/j.rcot.2016.07.018