Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Hélène Lemieux"'
Autor:
Hélène Lemieux, Pierre U. Blier
Publikováno v:
Metabolites, Vol 12, Iss 4, p 360 (2022)
Temperature shifts are a major challenge to animals; they drive adaptations in organisms and species, and affect all physiological functions in ectothermic organisms. Understanding the origin and mechanisms of these adaptations is critical for determ
Externí odkaz:
https://doaj.org/article/b41b381a84df47d780c18806ffae0ee4
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228710 (2020)
Our study revisits the role of cardiac mitochondrial adjustments during the progression of type 2 diabetes mellitus (T2DM), while considering age and sex as potential confounding factors. We used the Nile Grass rats (NRs) as the animal model. After w
Externí odkaz:
https://doaj.org/article/59b7d7afc3d74a97a7e9f730678d9ab2
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract For many neurodegenerative disorders, expression of a pathological protein by one cell type impedes function of other cell types, which in turn contributes to the death of the first cell type. In transgenic mice modelling Stargardt-like (STG
Externí odkaz:
https://doaj.org/article/a678339708ca45858f64f495a3c5912a
Autor:
Caroline-J. Kruse, David Stern, Ange Mouithys-Mickalad, Ariane Niesten, Tatiana Art, Hélène Lemieux, Dominique-M. Votion
Publikováno v:
Life, Vol 11, Iss 7, p 719 (2021)
Equine atypical myopathy is a seasonal intoxication of grazing equids. In Europe, this poisoning is associated with the ingestion of toxins contained in the seeds and seedlings of the sycamore maple (Acer pseudoplatanus). The toxins involved in atypi
Externí odkaz:
https://doaj.org/article/e8388473386f4095bcc46e5e867c64dd
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Fuel substrate supply and oxidative phosphorylation are key determinants of muscle performance. Numerous studies of mammalian mitochondria are carried out (i) with substrate supply that limits electron flow, and (ii) far below physiological
Externí odkaz:
https://doaj.org/article/59b9d2e8b934457799a51721c087f3f1
Publikováno v:
Cells, Vol 9, Iss 1, p 168 (2020)
Nor1, the third member of the Nr4a subfamily of nuclear receptor, is garnering increased interest in view of its role in the regulation of glucose homeostasis. Our previous study highlighted a proapoptotic role of Nor1 in pancreatic beta cells and sh
Externí odkaz:
https://doaj.org/article/e281ebc2d26c422196ffeed9f7819176
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208987 (2018)
BackgroundThe Nile rat (Arvicanthis niloticus) is an emerging laboratory model of type 2 diabetes. When fed standard rodent chow, the majority of males progress from hyperinsulinemia by 2 months to hyperglycemia by 6 months, while most females remain
Externí odkaz:
https://doaj.org/article/c2776097e0e34a608134905cb997e5df
Autor:
Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Andreas Affolter, Marcus C Schaub, Manoj Gandhi, Martin Hersberger, Blair E Warren, Hélène Lemieux, Hany F Sobhi, Alexander S Clanachan, Michael Zaugg
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87205 (2014)
Intralipid® administration at reperfusion elicits protection against myocardial ischemia-reperfusion injury. However, the underlying mechanisms are not fully understood.Sprague-Dawley rat hearts were exposed to 15 min of ischemia and 30 min of reper
Externí odkaz:
https://doaj.org/article/91ebaf547b944f14b0704108a8539e05
Autor:
Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Andreas Affolter, Manoj Gandhi, Martin Hersberger, Blair E Warren, Hélène Lemieux, Hany F Sobhi, Alexander S Clanachan, Michael Zaugg
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104971 (2014)
Insulin resistance and early type-2 diabetes are highly prevalent. However, it is unknown whether Intralipid® and sevoflurane protect the early diabetic heart against ischemia-reperfusion injury.Early type-2 diabetic hearts from Sprague-Dawley rats
Externí odkaz:
https://doaj.org/article/18aa3066e74f4db091943236b1850341
Autor:
Dominique-Marie Votion, Erich Gnaiger, Hélène Lemieux, Ange Mouithys-Mickalad, Didier Serteyn
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34890 (2012)
BACKGROUND: Within the animal kingdom, horses are among the most powerful aerobic athletic mammals. Determination of muscle respiratory capacity and control improves our knowledge of mitochondrial physiology in horses and high aerobic performance in
Externí odkaz:
https://doaj.org/article/802547c9c1f14287b251008f5cc6dcdb