Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hélène LaRue"'
Regulatory and memory T lymphocytes infiltrating prostate tumors predict long term clinical outcomes
Autor:
Oscar Eduardo Molina, Hélène LaRue, David Simonyan, Hélène Hovington, Benjamin Vittrant, Bernard Têtu, Vincent Fradet, Louis Lacombe, Alain Bergeron, Yves Fradet
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe localization, density but mostly the phenotype of tumor infiltrating lymphocytes (TIL) provide important information on the initial interaction between the host immune system and the tumor. Our objective was to assess the prognostic s
Externí odkaz:
https://doaj.org/article/eed7ff4b0c6d47a786ff782cfe835d29
Autor:
Oscar Eduardo Molina, Hélène LaRue, David Simonyan, Hélène Hovington, Bernard Têtu, Vincent Fradet, Louis Lacombe, Paul Toren, Alain Bergeron, Yves Fradet
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProstate cancer (PCa) shows considerable variation in clinical outcomes between individuals with similar diseases. The initial host-tumor interaction as assessed by detailed analysis of tumor infiltrating immune cells within the primary t
Externí odkaz:
https://doaj.org/article/5f55e5cf2747437ea5cf3c2283375225
Autor:
Mame-Kany Diop, Oscar Eduardo Molina, Mirela Birlea, Hélène LaRue, Hélène Hovington, Bernard Têtu, Louis Lacombe, Alain Bergeron, Yves Fradet, Dominique Trudel
Publikováno v:
Cancers, Vol 15, Iss 8, p 2217 (2023)
Intraductal carcinoma of the prostate (IDC-P) is an aggressive histological subtype of prostate cancer (PCa) detected in approximately 20% of radical prostatectomy (RP) specimens. As IDC-P has been associated with PCa-related death and poor responses
Externí odkaz:
https://doaj.org/article/5857ebb11e834aed909c906fb70d0302
Autor:
Chantal Guillemette, Yves Fradet, Mario Harvey, Molière Nguile-Makao, André Caron, Hélène Hovington, Alain Bergeron, Hélène Larue, Frédéric Pouliot, Éric Lévesque, Vincent Fradet, Louis Lacombe
Interaction between smoking (3 categories) and UGT1A1 genetic status (dominant model) in Cox multivariate model and the risk of bladder cancer recurrence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e00e8feb8cf901f431e303d801cc19
https://doi.org/10.1158/1940-6207.22526606.v1
https://doi.org/10.1158/1940-6207.22526606.v1
Autor:
Chantal Guillemette, Yves Fradet, Mario Harvey, Molière Nguile-Makao, André Caron, Hélène Hovington, Alain Bergeron, Hélène Larue, Frédéric Pouliot, Éric Lévesque, Vincent Fradet, Louis Lacombe
Cigarette smoking is the most important known risk factor for urinary bladder cancer. Selected arylamines in cigarette smoke are recognized human bladder carcinogens and undergo biotransformation through several detoxification pathways, such as the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a793296db1d37096a427373a4278ccfb
https://doi.org/10.1158/1940-6207.c.6545150.v1
https://doi.org/10.1158/1940-6207.c.6545150.v1
Publikováno v:
Nature Reviews Urology. 10:537-545
Toll-like receptors (TLRs) have an important role in the activation of both innate and adaptive immunity in response to pathogens and danger signals. These receptors are expressed in immune cells and in some epithelia. They are expressed in the epith
Autor:
Hélène Hovington, Bernard Têtu, Cherifa Ayari, André Caron, Yves Fradet, Alain Bergeron, Hélène LaRue, Vincent Fradet
Publikováno v:
Human Pathology. 44:1630-1637
A prognostic value for tumor-associated macrophages (TAMs) and tumor-infiltrating dendritic cells (TIDCs) has been reported in many human cancers. The objective of this study is to determine the prognostic value of CD83(+) mature TIDCs and CD68(+) TA
Autor:
Kate H. Moore, Hélène Hovington, Annie Lessard, Louis Lacombe, Hélène LaRue, Yves Fradet, Anis Aziz, Eva Latulippe
Publikováno v:
BJU International. 108:531-537
Study Type – Prognosis (case series) Level of Evidence 4 OBJECTIVE To determine whether the expression of cyclo-oxygenase (COX)-2 has an influence on survival and on the response to chemotherapy in invasive bladder cancer. PATIENTS AND METHODS A po
Autor:
Alain Bergeron, Yves Fradet, Hélène Hovington, Hélène LaRue, Louis Lacombe, François Harel, Valérie Picard
Publikováno v:
International Journal of Cancer. 125:1365-1371
Cancer-testis (CT) genes encode proteins that are ideal targets for cancer immunotherapy because of their restricted expression in normal tissues and frequent expression in cancers. We previously observed that MAGE-A9 was one of the CT genes most fre
Publikováno v:
International Journal of Cancer. 120:2170-2177
In a previous analysis, we showed that MAGE-As were the most frequently expressed cancer-testis antigens in human bladder tumours. Here, we further characterized by RT-PCR the expression of this family of genes by analyzing specifically MAGE-A3, -A4,