Výsledky vyhledávání - "Hélène Gary-Gouy"

OMIP-048 MC: Quantification of calcium sensors and channels expression in lymphocyte subsets by mass cytometry

Autor: Agnieszka Jaracz-Ros, Patrice Hémon, Hélène Gary-Gouy, Géraldine Schlecht-Louf, Françoise Bachelerie, Roman Krzysiek

Publikováno v: Cytometry Part A. 93:681-684

Calcium (Ca2+ ) signaling controls T-cell activation and functions. Ca2+ concentrations are locally detected and controlled by Ca2+ -sensors (STIM1 and 2 detecting the depletion from ER stores channels) and Ca2+ -channels (ORAI1-3 in the cell membran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55030b172bb3b63f4bf701c9458c5076
https://doi.org/10.1002/cyto.a.23504

Zobrazit plný text záznamu

Ectosomes from neutrophil-like cells down-regulate nickel-induced dendritic cell maturation and promote Th2 polarization

Autor: Claire Gueguen, Aude Gleizes, Roseline Gorges, Sylvie Chollet-Martin, Laurent Mascarell, Isabelle Turbica, Saadia Kerdine-Römer, Chantal Al Sabbagh, Hugo Tharinger, Yann Gallais, Hélène Gary-Gouy, Marc Pallardy

Publikováno v: Journal of Leukocyte Biology. 97:737-749

DCs are the first immune cells to be exposed to allergens, including chemical sensitizers, such as nickel, a human TLR4 agonist that induces DC maturation. In ACD, DCs can interact with PMNs that are recruited and activated, leading, in particular, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878dea9ff82c5403eec556bec124abed
https://doi.org/10.1189/jlb.3a0314-132rr

Zobrazit plný text záznamu

CXCR4 dysfunction in non-alcoholic steatohepatitis in mice and patients

Autor: Sylvie Naveau, Patrice Hemon, Karl Balabanian, Dominique Emilie, Olivier Robert, Hélène Gary-Gouy, Sophie Prevot, Marie-Laure Renoud, Gabriel Perlemuter, Hédia Boujedidi, Françoise Bachelerie, Hugo Tharinger, Alexandre Bignon, Anne-Marie Cassard-Doulcier

Publikováno v: Clinical Science. 128:257-267

Homing of inflammatory cells to the liver is key in the progression of non-alcoholic steatohepatitis (NASH). An abnormal response of CD4+ T-cells from obese mice to the chemotactic effect of CXCL12 has been reported but the mechanism involved in this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a430bf9c221c919f0a46bf6a0d8c90
https://doi.org/10.1042/cs20130833

Zobrazit plný text záznamu

High Membrane Cholesterol in CLL B-Cells and Differential Expression of Cholesterol Synthesis Genes in IG GENE-Unmutated vs Mutated Cells

Autor: Nader Hadife, Ali Dalloul, Marie C. Béné, Pierre Feugier, Torsten Haferlach, Hélène Gary-Gouy, Anne Kennel, Cécile Tomowiak

Publikováno v: British Journal of Medicine and Medical Research. 2:313-326

Objectives: Chronic lymphocytic leukaemia (CLL) is associated with abnormalities of the B-Cell Receptor (BCR) signalling, including low responsiveness to antigenic stimulation and constitutive phosphorylation of several components of the signalling p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c918c0c8e31477bdc52b54876b3914d
https://doi.org/10.9734/bjmmr/2012/944

Zobrazit plný text záznamu

Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells

Autor: Roman Krzysiek, Ali Dalloul, Ghyath Maarof, Ingrid Durand-Gasselin, Laurence Bouchet-Delbos, Hélène Gary-Gouy

Publikováno v: Blood. 115:1718-1726

Complex molecular mechanisms control B-cell fate to become a memory or a plasma cell. Interleukin-24 (IL-24) is a class II family cytokine of poorly understood immune function that regulates the cell cycle. We previously observed that IL-24 is strong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d9a1d2a96df6ea2ba5eb71452b5b92
https://doi.org/10.1182/blood-2009-05-220251

Zobrazit plný text záznamu

IL-24 Induces Apoptosis of Chronic Lymphocytic Leukemia B Cells Engaged into the Cell Cycle through Dephosphorylation of STAT3 and Stabilization of p53 Expression

Autor: Ghyath Maarof, Alexander Sainz-Perez, Ali Dalloul, Hélène Gary-Gouy, Anne Marfaing-Koka, Thierry de Revel, Françoise Gaudin

Publikováno v: The Journal of Immunology. 181:6051-6060

Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of long-lived monoclonal B cells mostly arrested at the G0/G1 phase of the cell cycle. CLL cells strongly express intracellular melanoma differentiation-associated gene-7 (MDA7)/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784ce75d18b24d17600533d5630a9a40
https://doi.org/10.4049/jimmunol.181.9.6051

Zobrazit plný text záznamu

Natural Phosphorylation of CD5 in Chronic Lymphocytic Leukemia B Cells and Analysis of CD5-Regulated Genes in a B Cell Line Suggest a Role for CD5 in Malignant Phenotype

Autor: Pierre Galanaud, Anne Marfaing-Koka, Alexander Sainz-Perez, Ali Dalloul, Hélène Gary-Gouy, Jean-Brice Marteau, Hélène Merle-Béral, Jozo Delic

Publikováno v: The Journal of Immunology. 179:4335-4344

Chronic lymphocytic leukemia (CLL) results in the accumulation of B cells, presumably reflecting the selection of malignant cell precursors with Ag combined with complex alterations in protein activity. Repeated BCR stimulation of normal B cells lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084e45515c832d53fc7e53c0909819b2
https://doi.org/10.4049/jimmunol.179.7.4335

Zobrazit plný text záznamu

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

Autor: Hélène Gary-Gouy, Alexander Sainz-Perez, P Galanaud, F Davi, A Portier, Ali Dalloul, H. Merle-Beral

Publikováno v: Leukemia. 20:498-504

Chronic lymphocytic leukemia (CLL)-B-cells are quiescent differentiated cells that produce interleukin (IL)-10 and accumulate due to resistance to apoptosis. The mechanisms underlying such resistance are poorly understood. Herein we show that all CLL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0bc516d855a31f14e10a542e3253ad
https://doi.org/10.1038/sj.leu.2404073

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání