Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hélène Freichels"'
Autor:
Katerina Makarova, Joanna J. Sajkowska-Kozielewicz, Katarzyna Zawada, Ewa Olchowik-Grabarek, Michał Aleksander Ciach, Krzysztof Gogolewski, Natalia Dobros, Paulina Ciechowicz, Hélène Freichels, Anna Gambin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The polyphenol content and antioxidant capacity of hyperforin and hypericin-standardized H. perforatum L. extracts may vary due to the harvest time. In this work, ethanol and ethanol–water extracts of air-dried and lyophilized flowers of H
Externí odkaz:
https://doaj.org/article/3bd3fc227b974e16b27f5e1d0dafe462
Autor:
Michał Aleksander Ciach, Hélène Freichels, Katerina Makarova, Krzysztof Gogolewski, Ewa Olchowik-Grabarek, Natalia Dobros, Joanna J. Sajkowska-Kozielewicz, Anna Gambin, Katarzyna Zawada, Paulina Ciechowicz
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The polyphenol content and antioxidant capacity of hyperforin and hypericin-standardized H. perforatum L. extracts may vary due to the harvest time. In this work, ethanol and ethanol-water extracts of air-dried and lyophilized flowers of H. perforatu
Publikováno v:
Scientific reports 6, 20536 (2016). doi:10.1038/srep20536
Scientific Reports
Scientific Reports
Scientific reports 6, 20536 (2016). doi:10.1038/srep20536
Published by Nature Publishing Group, London
Published by Nature Publishing Group, London
Autor:
Christine Jérôme, Hélène Freichels, Cécile S. Le Duff, Vincent Pourcelle, Jacqueline Marchand-Brynaert
Publikováno v:
Journal of Fluorine Chemistry. 140:62-69
In this paper, we describe a grafting methodology associated to a quantitative 19F NMR method (qNMR) for the conjugation of small molecules on a PEG building block aimed at click chemistry applications in the domain of drug delivery systems. Acetylen
Autor:
Rachel Auzély-Velty, Vincent Pourcelle, Christine Jérôme, Jacqueline Marchand-Brynaert, Hélène Freichels
Publikováno v:
Biomacromolecules. 13:760-768
Poly(lactide-co-glycolide) (PLGA) is extensively used in pharmaceutical applications, for example, in targeted drug delivery, because of biocompatibility and degradation rate, which is easily tuned by the copolymer composition. Nevertheless, synthesi
Autor:
Marlène Mengoni, G.H. van Lenthe, Jean-Philippe Ponthot, C. de Bien, Angélique Léonard, Romain Voide, Dominique Toye, Christine Jérôme, Ralph Müller, Hélène Freichels
Publikováno v:
International Journal for Numerical Methods in Biomedical Engineering. 28:273-287
SUMMARY Finite element (FE) models accurately compute the mechanical response of bone and bone-like materials when the models include their detailed microstructure. In order to simulate non-linear behavior, which currently is only feasible at the exp
Publikováno v:
Carbohydrate Polymers. 86:1093-1106
This paper aims at giving a comprehensive view of the research effort devoted to the preparation of sugar coated long-circulating degradable polymers intended for drug delivery applications. In the recent past, many research projects have focused on
Autor:
Cécile S. Le Duff, Vincent Pourcelle, Hélène Freichels, Christine Jérôme, Jacqueline Marchand-Brynaert
Publikováno v:
Macromolecular Rapid Communications. 32:616-621
a-Methoxy-v-alkyne poly(ethylene glycol) (PEG) was tagged with pendent N-hydroxy-succinimidyl activated esters by photografting of a molecular clip. This easily synthesized heterofunctional PEG was found to be a versatile building block for (i) conju
Publikováno v:
The International Journal of Artificial Organs. 34:152-160
Fluorescent-labeled aliphatic polyesters are essential materials for in vitro and in vivo studies of the behavior of these biodegradable polymers in interaction with cells or in a body. In particular, the direct cellular localization of drug delivery
Autor:
Nathalie Crokart, Hélène Freichels, Vincent Pourcelle, Nathalie Lecouturier, Véronique Préat, Christine Jérôme, Olivier Feron, Benoît Vroman, Fabienne Danhier, Jacqueline Marchand-Brynaert
Publikováno v:
Journal of Controlled Release. 140:166-173
Paclitaxel (PTX)-loaded PEGylated PLGA based nanoparticles (NP) have been previously described as more effective in vitro and in vivo than Taxol(R). The aim of this study was to test the hypothesis that our PEGylated PLGA-based nanoparticles grafted