The Ty1 integrase nuclear localization signal is necessary and sufficient for retrotransposon targeting to tRNA genes

Autor: Noé Palmic, Joël Acker, Pascale Lesage, Christine Conesa, Rachid Menouni, Amandine Bonnet, Hélène Fayol, Camille Grison, Amna Asif-Laidin, Indranil Adhya

SUMMARYIntegration of transposable elements into the genome is mutagenic. Mechanisms that target integration into relatively safe locations and minimize deleterious consequences for cell fitness have emerged during evolution. In budding yeast, the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84d2596ca0c3f9c58894f500e0368c6
https://doi.org/10.1101/2019.12.18.879569

Tye7 regulates yeast Ty1 retrotransposon sense and antisense transcription in response to adenylic nucleotides stress

Autor: Benoît Pinson, Hélène Fayol, Aurélie Tchalikian-Cosson, Carole Pennetier, Géraldine Servant, Fanny Coulpier, Sophie Lemoine, Antoine Bridier-Nahmias, Bertrand Daignan-Fornier, Anne-Laure Todeschini, Pascale Lesage

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2012, 40 (12), pp.5271-5282. ⟨10.1093/nar/gks166⟩
Nucleic Acids Research, Oxford University Press, 2012, 40 (12), pp.5271-5282. ⟨10.1093/nar/gks166⟩

International audience; Transposable elements play a fundamental role in genome evolution. It is proposed that their mobility, activated under stress, induces mutations that could confer advantages to the host organism. Transcription of the Ty1 LTR-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da147eedac96b9d4f281898e5a2a8ff
https://hal.science/hal-02119179