Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hélène F.E. Gleitz"'
Autor:
Jessica E. Pritchard, Juliette E. Pearce, Inge A.M. Snoeren, Stijn N.R. Fuchs, Katrin Götz, Fabian Peisker, Silke Wagner, Adam Benabid, Niklas Lutterbach, Vanessa Klöker, James S. Nagai, Monica T. Hannani, Anna K. Galyga, Ellen Sistemich, Bella Banjanin, Niclas Flosdorf, Eric Bindels, Kathrin Olschok, Katharina Biaesch, Nicolas Chatain, Neha Bhagwat, Andrew Dunbar, Rita Sarkis, Olaia Naveiras, Marie-Luise Berres, Steffen Koschmieder, Ross L. Levine, Ivan G. Costa, Hélène F.E. Gleitz, Rafael Kramann, Rebekka K. Schneider
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113608- (2024)
Summary: The role of hematopoietic Hedgehog signaling in myeloproliferative neoplasms (MPNs) remains incompletely understood despite data suggesting that Hedgehog (Hh) pathway inhibitors have therapeutic activity in patients. We aim to systematically
Externí odkaz:
https://doaj.org/article/79a625e34918435f841f28673c9cdf62
Autor:
Stuart Ellison, Aiyin Liao, Hélène F.E. Gleitz, Helen Parker, Laura Booth, John Robinson, Shaun Wood, Jessica Taylor, Rebecca Holley, Brian W. Bigger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101127- (2023)
Mucopolysaccharidosis type II (MPSII) is a pediatric lysosomal storage disease caused by deficiencies in the IDS (iduronate-2-sulfatase) gene resulting in accumulation of glycosaminoglycans, multisystem disease, and profound neurodegeneration in seve
Externí odkaz:
https://doaj.org/article/9b7c441d02a944129089fa20c2a74363
Publikováno v:
Haematologica, Vol 108, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/57b6758d560448fb9d404568ada27306
Autor:
Hélène F.E. Gleitz, Inge A.M. Snoeren, Stijn N.R. Fuchs, Nils B. Leimkühler, Rebekka K. Schneider
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100538- (2021)
Summary: Bone marrow (BM) mesenchymal stromal cells play an important role in regulating stem cell quiescence and homeostasis; they are also key contributors to various hematological malignancies. However, human bone marrow stromal cells are difficul
Externí odkaz:
https://doaj.org/article/be486253b04e42b9bf0880d5bcea4cf7
Publikováno v:
HemaSphere, Vol 3, Pp 142-145 (2019)
Externí odkaz:
https://doaj.org/article/027aedf66b8d4c1f97c1cdcea06bab14
Autor:
Jessica E. Pritchard, Juliette E. Pearce, Inge A.M. Snoeren, Stijn N.R. Fuchs, Katrin Götz, Fabian Peisker, Silke Wagner, Adam Benabid, Niklas Lutterbach, Anna K. Galyga, James S. Nagai, Vanessa Krämer, Monica T. Hannani, Eric Bindels, Kathrin Olschok, Nicolas Chatain, Neha Bhagwat, Andrew Dunbar, Marie-Luise Berres, Steffen Koschmieder, Ross L. Levine, Ivan Costa, Hélène F.E. Gleitz, Rafael Kramann, Rebekka Schneider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::815ad8da44dab9254594abe7101295c7
https://doi.org/10.2139/ssrn.4381686
https://doi.org/10.2139/ssrn.4381686
Autor:
Christoph Kuppe, Li Ronghui, Evelyn Wing-Ying Tai, Rafael Kramann, Eric Bindels, Nils B. Leimkühler, Tim H. Brümmendorf, Ines Gütgemann, Inge A.M. Snoeren, Philippe Krebs, Ivan G. Costa, Guntram Buesche, Steffen Koschmieder, Hans Kreipe, Stijn N.R. Fuchs, Peter Boor, Ursula S.A. Stalmann, Rebekka K. Schneider, Yara Banz, Hélène F.E. Gleitz, Martina Crysandt
Publikováno v:
SSRN Electronic Journal
Functional contributions of individual members of the bone marrow microenvironment to myelofibrosis (MF) in patients with myeloproliferative neoplasms (MPN) are incompletely understood. Consequently, we aimed to generate a comprehensive map of the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782bf0c34568495e6e53e2c5d63a4505
Publikováno v:
The Journal of Pathology. 245:138-146
Bone marrow fibrosis is the continuous replacement of blood-forming cells in the bone marrow with excessive scar tissue, leading to failure of the body to produce blood cells and ultimately to death. Myofibroblasts are fibrosis-driving cells and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ef86cd77698318ffe4ebca999053348
https://doi.org/10.1002/path.5078
https://doi.org/10.1002/path.5078
Autor:
Christoph Kuppe, Ines Gütgemann, Philippe Krebs, Rafael Kramann, Bella Banjanin, Evelyn Wing-Ying Tai, Inge A.M. Snoeren, King H. Lam, Peter Boor, Nils B. Leimkühler, Hans Kreipe, Ivan G. Costa, Thomas Vogl, Li Ronghui, Tim H. Brümmendorf, Guntram Büsche, Steffen Koschmieder, Rebekka K. Schneider, Hélène F.E. Gleitz, Stijn N.R. Fuchs, Eric Bindels, Yara Banz, Martina Crysandt, James Shiniti Nagai, Ursula S.A. Stalmann
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 28(4), 637-652.e8. Cell Press
Leimkühler, Nils B.; Gleitz, Hélène F.E.; Ronghui, Li; Snoeren, Inge A.M.; Fuchs, Stijn N.R.; Nagai, James S.; Banjanin, Bella; Lam, King H.; Vogl, Thomas; Kuppe, Christoph; Stalmann, Ursula S.A.; Büsche, Guntram; Kreipe, Hans; Gütgemann, Ines; Krebs, Philippe; Banz, Yara; Boor, Peter; Tai, Evelyn Wing-Ying; Brümmendorf, Tim H.; Koschmieder, Steffen; ... (2021). Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell stem cell, 28(4), 637-652.e8. Elsevier 10.1016/j.stem.2020.11.004
Cell Stem Cell, 28(4), 637-652.e8. Cell Press
Leimkühler, Nils B.; Gleitz, Hélène F.E.; Ronghui, Li; Snoeren, Inge A.M.; Fuchs, Stijn N.R.; Nagai, James S.; Banjanin, Bella; Lam, King H.; Vogl, Thomas; Kuppe, Christoph; Stalmann, Ursula S.A.; Büsche, Guntram; Kreipe, Hans; Gütgemann, Ines; Krebs, Philippe; Banz, Yara; Boor, Peter; Tai, Evelyn Wing-Ying; Brümmendorf, Tim H.; Koschmieder, Steffen; ... (2021). Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell stem cell, 28(4), 637-652.e8. Elsevier 10.1016/j.stem.2020.11.004
Summary Functional contributions of individual cellular components of the bone-marrow microenvironment to myelofibrosis (MF) in patients with myeloproliferative neoplasms (MPNs) are incompletely understood. We aimed to generate a comprehensive map of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e520733f5d3714450a95c26c6d646b1
https://pubmed.ncbi.nlm.nih.gov/33301706
https://pubmed.ncbi.nlm.nih.gov/33301706
Autor:
Ioanna Triviai, Julio Saez-Rodriguez, Nicolaus Kröger, Remco Hoogenboezem, Guntram Büsche, Rafael Kramann, Bella Banjanin, Sylvia Menzel, Aurelien Dugourd, Jessica E Pritchard, Inge A.M. Snoeren, Hans Kreipe, Stefan Rose-John, Shannon Elf, Rebekka K. Schneider, Eric M.J. Bindels, Nils B. Leimkühler, Hélène F.E. Gleitz, Stijn N.R. Fuchs, Neele Schumacher, Susanne Ziegler
Publikováno v:
Blood
Blood, 136(18), 2051-2064. American Society of Hematology
Blood, 136(18), 2051-2064. American Society of Hematology
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) that leads to progressive bone marrow (BM) fibrosis. Although the cellular mutations involved in the pathogenesis of PMF have been extensively investigated, the sequential events that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2792f16adde410147ae399191ef2134
https://pubmed.ncbi.nlm.nih.gov/33119760
https://pubmed.ncbi.nlm.nih.gov/33119760