Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Hélène Cannelle"'
1
Akademický článek
Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis
Autor: Cécile Cros, Marielle Margier, Hélène Cannelle, Julie Charmetant, Nicolas Hulo, Laurent Laganier, Alessia Grozio, Matthias Canault
Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)
Peritonitis and subsequent sepsis lead to high morbidity and mortality in response to uncontrolled systemic inflammation primarily mediated by macrophages. Nicotinamide adenine dinucleotide (NAD+) is an important regulator of oxidative stress and imm
Externí odkaz: https://doaj.org/article/ce91d69c18a449668487aacbe89ce37e
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2
Akademický článek
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.
Autor: Karin Schaeuble, Hélène Cannelle, Stéphanie Favre, Hsin-Ying Huang, Susanne G Oberle, Daniel E Speiser, Dietmar Zehn, Sanjiv A Luther
Publikováno v: PLoS Biology, Vol 17, Iss 7, p e3000072 (2019)
Lymphoid T-zone fibroblastic reticular cells (FRCs) actively promote T-cell trafficking, homeostasis, and expansion but can also attenuate excessive T-cell responses via inducible nitric oxide (NO) and constitutive prostanoid release. It remains uncl
Externí odkaz: https://doaj.org/article/f70279d9635b4e14b2387e73606c7a17
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3
Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection
Autor: Matthew B. Buechler, Shannon J. Turley, Nagham Alouche, Tom Cupedo, Burkhard Ludewig, Patricia Aparicio‐Domingo, Natalie Papazian, Hélène Cannelle, Sandra M. Kallert, Sylvain Nguyen, Sanjiv A. Luther, Stéphanie Favre, Daniel D. Pinschewer
Publikováno v: European Journal of Immunology, 51(1), 76-90. Wiley-VCH
European Journal of Immunology
The importance of interleukin (IL)‐33 in promoting effective antiviral immune responses is evident, yet the critical cellular sources of IL‐33 in homeostasis and infection are largely unknown. In this issue of the European Journal of Immunology,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00d80d0ab954dc3f1d458eb6ba8829b
https://doi.org/10.1002/eji.201948413
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5
Safety evaluation after acute and sub-chronic oral administration of high purity nicotinamide mononucleotide (NMN-C®) in Sprague-Dawley rats
Autor: Hélène Cannelle, Cecile Cros, Alessia Grozio, Laurent Laganier, Matthias Canault
Publikováno v: Food and Chemical Toxicology. 150:112060
β-nicotinamide mononucleotide (NMN) is a natural molecule intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Preclinical evidences point to the beneficial effect of NMN administration on several age-related conditions. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1736d6e53e13ffd0200608da758d6e19
https://doi.org/10.1016/j.fct.2021.112060
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6
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts
Autor: Karin Schaeuble, Stéphanie Favre, Dietmar Zehn, Daniel E. Speiser, Hélène Cannelle, Sanjiv A. Luther, Susanne Oberle, Hsin-Ying Huang
Publikováno v: PLoS Biology, Vol 17, Iss 7, p e3000072 (2019)
PLOS Biology
PLoS biology, vol. 17, no. 7, pp. e3000072
PLoS Biology
Lymphoid T-zone fibroblastic reticular cells (FRCs) actively promote T-cell trafficking, homeostasis, and expansion but can also attenuate excessive T-cell responses via inducible nitric oxide (NO) and constitutive prostanoid release. It remains uncl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4806e8ec0fe2623baf2e627e52e086
https://mediatum.ub.tum.de/1545390
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9
Akademický článek
Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice
Autor: Marielle Margier, Chisaka Kuehnemann, Nicolas Hulo, Jazmin Morales, Prasanna Vadhana Ashok Kumaar, Cecile Cros, Helene Cannelle, Julie Charmetant, Eric Verdin, Matthias Canault, Alessia Grozio
Publikováno v: Cells, Vol 12, Iss 1, p 108 (2022)
Doxorubicin (Doxo) is a widely used antineoplastic drug with limited clinical application due to its deleterious dose-related side effects. We investigated whether nicotinamide mononucleotide (NMN) could protect against Doxo-induced cardiotoxicity an
Externí odkaz: https://doaj.org/article/b9e87ca6e82849e4bbd7eac6c00018b8
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