Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Hélène Barreteau"'
Autor:
Marko Jukič, Rodolphe Auger, Victor Folcher, Matic Proj, Hélène Barreteau, Stanislav Gobec, Thierry Touzé
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2360-2371 (2022)
Increasing resistance to common antibiotics is becoming a major challenge that requires the development of new antibacterial agents. Peptidoglycan is an essential heteropolymer of the bacterial envelope that ensures the integrity and shape of all bac
Externí odkaz:
https://doaj.org/article/c46b1d1a607541adb2ed8da2b9d1a317
Autor:
Martina Hrast, Kaja Rožman, Iza Ogris, Veronika Škedelj, Delphine Patin, Matej Sova, Hélène Barreteau, Stanislav Gobec, Simona Golič Grdadolnik, Anamarija Zega
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1010-1017 (2019)
The Mur ligases form a series of consecutive enzymes that participate in the intracellular steps of bacterial peptidoglycan biosynthesis. They therefore represent interesting targets for antibacterial drug discovery. MurC, D, E and F are all ATP-depe
Externí odkaz:
https://doaj.org/article/611a82a2fe88425aaa24c3fa2a9502bd
Publikováno v:
Antibiotics, Vol 10, Iss 9, p 1109 (2021)
The misuse of antibiotics during the last decades led to the emergence of multidrug resistant pathogenic bacteria. This phenomenon constitutes a major public health issue. Consequently, the discovery of new antibacterials in the short term is crucial
Externí odkaz:
https://doaj.org/article/0e2f065abad64b8d85cfca84fb1e618b
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
We report the successful implementation of virtual screening in the discovery of new inhibitors of undecaprenyl pyrophosphate synthase (UppS) from Escherichia coli. UppS is an essential enzyme in the biosynthesis of bacterial cell wall. It catalyzes
Externí odkaz:
https://doaj.org/article/b48f032d69444f16ae8ccd3b922d1a92
Autor:
Roman Šink, Miha Kotnik, Anamarija Zega, Hélène Barreteau, Stanislav Gobec, Didier Blanot, Andréa Dessen, Carlos Contreras-Martel
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152075 (2016)
The biosynthetic pathway of peptidoglycan, an essential component of bacterial cell wall, is a well-recognized target for antibiotic development. Peptidoglycan precursors are synthesized in the bacterial cytosol by various enzymes including the ATP-h
Externí odkaz:
https://doaj.org/article/427118feda6c49b99ecd543b2a6e5d61
Publikováno v:
Food Technology and Biotechnology, Vol 44, Iss 3, Pp 323-333 (2006)
Recent research in the area of carbohydrate food ingredients has shown the efficiency of oligosaccharides when they are used as prebiotics or biopreservatives. Considering the former, they have various origins and structures, whereas the latter are d
Externí odkaz:
https://doaj.org/article/9661a44d628d4086a0e9ee58867dc188
Autor:
Dimitri Chérier, Sean Giacomucci, Delphine Patin, Ahmed Bouhss, Thierry Touzé, Didier Blanot, Dominique Mengin-Lecreulx, Hélène Barreteau
Publikováno v:
Antibiotics, Vol 5, Iss 4, p 36 (2016)
Colicins are bacterial toxins produced by some Escherichia coli strains. They exhibit either enzymatic or pore-forming activity towards a very limited number of bacterial species, due to the high specificity of their reception and translocation syste
Externí odkaz:
https://doaj.org/article/79520a429a814323a0942fdf2b8309c4
Autor:
Mihael Simčič, Izidor Sosič, Milan Hodošček, Hélène Barreteau, Didier Blanot, Stanislav Gobec, Simona Golič Grdadolnik
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52817 (2012)
A series of optimized sulfonamide derivatives was recently reported as novel inhibitors of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD). These are based on naphthalene-N-sulfonyl-D-glutamic acid and have the D-glutamic acid replaced with
Externí odkaz:
https://doaj.org/article/82e2208f27304210bd04393e04fc33af
Autor:
Marc Veyrier, C. Karczewski, Vanessa Bloch, F. Iskra, M.L. Vignes, Hélène Barreteau, L. Kubiak, P. Cavagna, L. Nicolas
Publikováno v:
Le Pharmacien Hospitalier et Clinicien. 54:145-155
Resume Introduction L’automatisation de la dispensation individuelle nominative induit des changements de pratique sur l’ensemble du circuit du medicament, c’est pourquoi l’integration d’un automate doit etre anticipee. Une analyse prelimin
Autor:
Hélène Barreteau, Pauline Cavagna, Vanessa Bloch, Julien Azuar, Maeva Fortias, Louise Nicolas, Franck Bellivier, François Naccache, Thomas Barré, Marc Veyrier, Florence Vorspan
Publikováno v:
Therapies. 73:495-500
Summary Intranasal naloxone aims at preventing opioid overdose related deaths in active drug users. In France, it has been available since July 2016 through a temporary approval which requires a hospital-based pharmacy and a nominative registration o