Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hélène A. Gussin"'
Autor:
Sujatha P Koduvayur, Hélène A Gussin, Rajni Parthasarathy, Zengping Hao, Brian K Kay, David R Pepperberg
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87964 (2014)
The abundance and physiological importance of GABAA receptors in the central nervous system make this neurotransmitter receptor an attractive target for localizing diagnostic and therapeutic biomolecules. GABAA receptors are expressed within the reti
Externí odkaz:
https://doaj.org/article/2e81072dc8494f7c8850776891cd5029
Autor:
Jerry A. Krishnan, Linda J. Walsh, Janos Porszasz, Julian Husbands, Jamie L. Sullivan, Hélène A. Gussin, Kristen E. Holm, Valentin Prieto-Centurion, Robert A. Sandhaus, Scott Cerreta, Richard Casaburi
Publikováno v:
The Patient - Patient-Centered Outcomes Research. 9:271-279
Patients are increasingly viewed as key stakeholders who can contribute in meaningful ways to clinical research and are emphasized in research funded by the Patient-Centered Outcomes Research Institute (PCORI). We are not aware of other peer-reviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dec4d86c3cf856fd0778dfb359dbf41
https://doi.org/10.1007/s40271-015-0150-z
https://doi.org/10.1007/s40271-015-0150-z
Autor:
Valentin Prieto-Centurion, Jamie L. Sullivan, Byron Thomashow, Jerry A. Krishnan, Farhan Zaidi, Hélène A. Gussin
Publikováno v:
Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation. 2:70-80
About 1 in 5 patients hospitalized for exacerbations of chronic obstructive pulmonary disease (COPD) in the United States are readmitted within 30 days. The U.S. Centers for Medicare and Medicaid Services has recently expanded its Hospital Readmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03363272ef7f3b969a1040279f9470d3
https://doi.org/10.15326/jcopdf.2.1.2014.0148
https://doi.org/10.15326/jcopdf.2.1.2014.0148
Publikováno v:
Analytical Biochemistry. 432:49-57
This study reports the preparation and characterization of cysteine-terminated B-domain (Bd-cys) of Staphylococcus aureus protein A, in combination with immunoglobulin G (IgG) antibodies directed against the ρ1 and α1 subunits of GABA(A) receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca57f14581234a6598f327048796f73
https://doi.org/10.1016/j.ab.2012.08.031
https://doi.org/10.1016/j.ab.2012.08.031
Autor:
David R. Pepperberg, Haohua Qian, Deborah M. Little, Hélène A. Gussin, Sandra J. Rosenthal, Ian D. Tomlinson, Niraj J. Muni
Publikováno v:
Bioconjugate Chemistry. 21:1455-1464
Highly fluorescent CdSe quantum dots (qdots) can serve as a platform for tethering multiple copies of a receptor-targeted ligand, affording study of how the level of multivalency affects receptor binding. We previously showed that qdots conjugated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeedf69dd7ead861cc64d9ba38cbd818
https://doi.org/10.1021/bc100050s
https://doi.org/10.1021/bc100050s
Autor:
Jie Liang, Haohua Qian, David R. Pepperberg, Hélène A. Gussin, Feng Feng, Yan Yuan Tseng, Larisa Adamian, Niraj J. Muni
Publikováno v:
Protein Science. 18:2371-2383
The homopentameric rho1 GABA(C) receptor is a ligand-gated ion channel with a binding pocket for gamma-aminobutyric acid (GABA) at the interfaces of N-terminal extracellular domains. We combined evolutionary analysis, structural modeling, and experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b04e17c809d7bfe4beed697b17b7d5c
https://doi.org/10.1002/pro.247
https://doi.org/10.1002/pro.247
Publikováno v:
Fetal Diagnosis and Therapy. 20:64-69
Objectives: To establish optimal culture conditions for fetal endothelial cells, and determine whether these can be used for preferential expansion of fetal cells from maternal blood. Methods: Human adult microvascular and umbilical vein endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d758ea8be1b91827d22d67ab4360f93
https://doi.org/10.1159/000081372
https://doi.org/10.1159/000081372
Publikováno v:
Prenatal Diagnosis. 24:189-193
Objectives We hypothesized that fetal cells in maternal blood that do not respond to hematopoietic culture conditions represent endothelial cells. We investigated whether endothelial progenitor cells of fetal origin may be selected from maternal bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36974e24dadad98684ad79c470ed9b1
https://doi.org/10.1002/pd.832
https://doi.org/10.1002/pd.832
Autor:
Sherman Elias, Hélène A. Gussin
Publikováno v:
Human Reproduction Update. 8:523-527
The isolation and analysis of fetal cells from maternal blood would allow non-invasive prenatal genetic screening and diagnosis. Over the past decade, progress has been made towards this goal using various enrichment strategies and analysis by fluore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7901936983e085c75e76dd799cee3470
https://doi.org/10.1093/humupd/8.6.523
https://doi.org/10.1093/humupd/8.6.523
Autor:
Michael Markos, Min J. Joo, Bharati Prasad, Patrick O. Godwin, Nina Bracken, Valentin Prieto-Centurion, Sharmilee M. Nyenhuis, Jamie L. Sullivan, Byron Thomashow, Bruce R. Schatz, Norma I. Ramey, Mark V. Williams, Barry R. Pittendrigh, Jerry A. Krishnan, Howard A. Jaffe, Hélène A. Gussin, Ravi Kalhan, Robert J. DiDomenico, Alan S. Pickard
Publikováno v:
Annals of the American Thoracic Society. 11(3)
Approximately 20% of patients hospitalized for COPD exacerbations in the United States will be readmitted within 30 days. The Centers for Medicare and Medicaid Services has recently proposed to revise the Hospital Readmissions Reduction Program to fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb9f8088a62779337d3f8694674f611
https://pubmed.ncbi.nlm.nih.gov/24423379
https://pubmed.ncbi.nlm.nih.gov/24423379