Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Héctor R. Contreras"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: One of the primary obstacles faced by individuals with advanced colorectal cancer (CRC) is the potential development of acquired chemoresistance as the disease advances. Studies have indicated a direct association between elevated level
Externí odkaz:
https://doaj.org/article/a31bbc1af431457ba87c309b6ee6d65b
Autor:
Diego Figueroa, Javiera Ríos, Oscar F. Araneda, Héctor R. Contreras, Miguel L. Concha, Carlos García
Publikováno v:
Life, Vol 13, Iss 1, p 15 (2022)
Toxins of the OA-group (okadaic acid, OA; dinophysistoxin-1, DTX-1) are the most prevalent in the fjords of southern Chile, and are characterized by their potential harmful effects on aquatic organisms. The present study was carried out to determine
Externí odkaz:
https://doaj.org/article/805553ac74d047e7a61c8502b9e98116
Autor:
Glauben Landskron, Marjorie De la Fuente López, Karen Dubois-Camacho, David Díaz-Jiménez, Octavio Orellana-Serradell, Diego Romero, Santiago A. Sepúlveda, Christian Salazar, Daniela Parada-Venegas, Rodrigo Quera, Daniela Simian, María-Julieta González, Francisco López-Köstner, Udo Kronberg, Mario Abedrapo, Iván Gallegos, Héctor R. Contreras, Cristina Peña, Guillermo Díaz-Araya, Juan Carlos Roa, Marcela A. Hermoso
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/c83a3bbb93fa43d0bbb6b208d5ab203b
Autor:
Glauben Landskron, Marjorie De la Fuente López, Karen Dubois-Camacho, David Díaz-Jiménez, Octavio Orellana-Serradell, Diego Romero, Santiago A. Sepúlveda, Christian Salazar, Daniela Parada-Venegas, Rodrigo Quera, Daniela Simian, María-Julieta González, Francisco López-Köstner, Udo Kronberg, Mario Abedrapo, Iván Gallegos, Héctor R. Contreras, Cristina Peña, Guillermo Díaz-Araya, Juan Carlos Roa, Marcela A. Hermoso
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In colorectal cancer (CRC), cancer-associated fibroblasts (CAFs) are the most abundant component from the tumor microenvironment (TM). CAFs facilitate tumor progression by inducing angiogenesis, immune suppression and invasion, thus altering the orga
Externí odkaz:
https://doaj.org/article/e28d38252ed04169b03812db7b1cd4d6
Publikováno v:
Toxins, Vol 12, Iss 3, p 179 (2020)
Diarrhetic shellfish poisoning (DSP) is a syndrome caused by the intake of shellfish contaminated with a group of lipophilic and thermostable toxins, which consists of okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2). These
Externí odkaz:
https://doaj.org/article/f2ac04e7ddab40be86a669608b4280aa
Publikováno v:
Toxins, Vol 9, Iss 6, p 190 (2017)
The saxitoxin-group (STX-group) corresponds to toxic metabolites produced by cyanobacteria and dinoflagellates of the genera Alexandrium, Gymnodinium, and Pyrodinium. Over the last decade, it has been possible to extrapolate the areas contaminated wi
Externí odkaz:
https://doaj.org/article/ec589ffc145a4a8d851ec41240a7a63c
Publikováno v:
Advances in experimental medicine and biology. 1393
Prostate cancer (PCa) incidence has increased during the last decades, becoming one of the leading causes of death by cancer in men worldwide. During an extended period of prostate cancer, malignant cells are androgen-sensitive being testosterone the
Autor:
Christian Huidobro, Alejandro Mercado, Enrique A. Castellón, Apolo Salgado, Catherine Sánchez, Felipe Carvajal, Héctor R. Contreras
Publikováno v:
International Journal of Radiation Biology. 97:1555-1562
GnRH analogues are widely used as neoadyuvant agents for radiotherapy in prostate cancer (PCa) patients, with well documented effects in reducing tumor bulk and increasing progression-free survival. GnRH analogs act locally in the prostate by trigger
Autor:
Fernanda López-Moncada, María José Torres, Boris Lavanderos, Oscar Cerda, Enrique A. Castellón, Héctor R. Contreras
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 5874
Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling and is abundant in bone m
Autor:
Paula Maloberti, María T. Torres, Facundo José Salinas, Natalia Raquel Salvetti, Pablo Lorenzano Menna, Graciela Caroca, Daniel E. Gomez, Ulises Daniel Orlando, María Mercedes Bigi, Hugo Hector Ortega, Jesica Giselle Prada, Ana Fernanda Castillo, Juan B. Rodriguez, Angela Rosario Solano, Melina Andrea Dattilo, Belkis Ester Marelli, Mayra Agustina Ríos Medrano, Ernesto J. Podestá, Sebastián Indo, Sergio H. Szajnman, Héctor R. Contreras
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Acyl-CoA synthetase 4 (ACSL4) is an isoenzyme of the fatty acid ligase-coenzyme-A family taking part in arachidonic acid metabolism and steroidogenesis. ACSL4 is involved in the development of tumor aggressiveness in breast and prostate tumors throug