Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Héctor Martín Merinero"'
Autor:
Alex González-Alsina, Héctor Martín-Merinero, Margalida Mateu-Borrás, María Verd, Antonio Doménech-Sánchez, Joanna B. Goldberg, Santiago Rodríguez de Córdoba, Sebastián Albertí
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections. The outcome of these infections depends on the virulence of the microorganism as well as host-related conditions and factors. The complement system plays a crucial role i
Externí odkaz:
https://doaj.org/article/2e235488fce644b8828bca623031de07
Autor:
Alex González-Alsina, Héctor Martín-Merinero, Margalida Mateu-Borrás, María Verd, Antonio Doménech-Sánchez, Joanna B. Goldberg, Santiago Rodríguez de Córdoba, Sebastián Albertí
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Pseudomonas aeruginosa is an important human opportunistic pathogen responsible for a wide range of infections. The complement system is the main early host defense mechanism to control these infections. P. aeruginosa counteracts complement attack by
Externí odkaz:
https://doaj.org/article/f93edac34b274a6e883adb3b4048a991
Autor:
Francisco J. Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E. Shepard, Santiago Rodríguez de Córdoba, M. Cristina Vega
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Complement activation on foreign cell surfaces leads to the generation of complement opsonins, which activate complement receptor type 3 (CR3) and pathogen clearance by macrophages. Here, the authors reveal structural basis of the interaction between
Externí odkaz:
https://doaj.org/article/78117c6d84b049e588f1750afdba4664
Autor:
Emilia Arjona, Malkoa Michelena, Elena Gómez-Rubio, Richard J.H. Smith, Rui-Ru Ji, Renee X. Goodfellow, Yuzhou Zhang, Héctor Martín Merinero, Santiago Rodríguez de Córdoba, Guillermo del Angel
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Blood
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
instname
Blood
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening thrombotic microangiopathy, and complement dysregulation due to pathogenic variants in factor H (FH) is a recognized cause. The clinical utility of genetic testing in aHUS is limited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b0cab3d1cfb45eedadba73ad26a613
http://hdl.handle.net/10261/245480
http://hdl.handle.net/10261/245480
Autor:
Francisco Javier Cañada, Constantino Fernández, Elena Gómez-Rubio, Sonsoles Martín-Santamaría, Amaia Pereda, Marta Subias, Lucía López, Héctor Martín Merinero, Elena Goicoechea de Jorge, Santiago Rodríguez de Córdoba
33 p.-7 fig.
Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable b
Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fca5ddaa7d3a934e5e19e23e5644c54
http://hdl.handle.net/10261/236465
http://hdl.handle.net/10261/236465
Autor:
Héctor Martín Merinero, Zhang, Yuzhou, Bolanos, Emilia Arjona, Goodfellow, Renee, Michelena, Malkoa, Smith, Richard J. H., Cordoba, Santiago Rodriguez
Publikováno v:
Web of Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
1 p.
Background: Atypical hemolytic uremic syndrome (aHUS) isa life-threatening thrombotic microangiopathy that can progress,when untreated, to end-stage renal disease. Most frequently, aHUSis caused by complement dysregulation due to pathogenic
Background: Atypical hemolytic uremic syndrome (aHUS) isa life-threatening thrombotic microangiopathy that can progress,when untreated, to end-stage renal disease. Most frequently, aHUSis caused by complement dysregulation due to pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8ab41234d68dc6afcf6128c1ece28eb8
http://hdl.handle.net/10261/257308
http://hdl.handle.net/10261/257308
Autor:
Emilia Arjona, Jesús García-Fernández, Héctor Martín Merinero, Agustín Tortajada, Santiago Rodríguez de Córdoba, Sheila Pinto García
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
30 p.-7 fig.
Genetic analyses in atypical hemolytic uremic syndrome (aHUS) and C3-glomerulopathy (C3G) patients have provided an excellent understanding of the genetic component of the disease and informed genotype-phenotype correlations support
Genetic analyses in atypical hemolytic uremic syndrome (aHUS) and C3-glomerulopathy (C3G) patients have provided an excellent understanding of the genetic component of the disease and informed genotype-phenotype correlations support
Autor:
Héctor Martín Merinero, Fernando A. González-Fernández, Santiago Rodríguez de Córdoba, Rafael Fores, Ana Villegas, Emilio Ojeda, A. López, Jaouad Anter, Margarita López-Trascasa, Marta Subías Hidalgo, Sheila Pinto García
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
35 p.-3 fig.-4 tab. Subías, Marta et al.
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia characterized by complement-mediated intravascular hemolysis that is effectively treated with eculizumab. However, treatment resp
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia characterized by complement-mediated intravascular hemolysis that is effectively treated with eculizumab. However, treatment resp
Autor:
Giuseppe Remuzzi, Santiago Rodríguez de Córdoba, Marina Noris, Sheila Pinto García, Héctor Martín Merinero, Jesús García-Fernández, Sara Gastoldi, Agustín Tortajada, Emilia Arjona, Elena Goicoechea de Jorge, Mercedes Cao
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
10 p.-6 fig.-1 tab.
Atypical hemolytic uremic syndrome (aHUS), a rare form of thrombotic microangiopathy caused by complement pathogenic variants, mainly affects the kidney microvasculature. A retrospective genetic analysis in our aHUS cohort (n
Atypical hemolytic uremic syndrome (aHUS), a rare form of thrombotic microangiopathy caused by complement pathogenic variants, mainly affects the kidney microvasculature. A retrospective genetic analysis in our aHUS cohort (n
Autor:
Santiago Rodríguez de Córdoba, Daniel Chacón, Ana V. Marin, Héctor Martín Merinero, Agustín Tortajada, José R. Regueiro, Ùscar Sabúz, Emilia Arjona
Publikováno v:
Molecular Immunology. 102:221