Výsledky vyhledávání - "Héctor Lázare"

Akademický článek

Unintentional weight loss as presenting form of Whipple’s disease. Role of PET-CT scanning and review of the literature.

Autor: Emilio Páez Guillán, Alba García Villafranca, Héctor Lazaré Iglesias, José Antonio Díaz Peromingo

Publikováno v: Galicia Clínica, Vol 81, Iss 3, Pp 90-92 (2020)

Whipple’s disease (W.D.) is a multisystemic chronic infectious disorder very rare with polymorphic clinical presentation. Diagnosis can be difficult, especially when early presentation is not the classic form. We report a case presented as isolated

Externí odkaz: https://doaj.org/article/283343a426e346dda306406bc27eb835

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Akademický článek

MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles

Autor: Martín Santamarina-García, Jenifer Brea-Iglesias, Jesper Bertram Bramsen, Mar Fuentes-Losada, Francisco Javier Caneiro-Gómez, José Ángel Vázquez-Bueno, Héctor Lázare-Iglesias, Natalia Fernández-Díaz, Laura Sánchez-Rivadulla, Yoel Z. Betancor, Miriam Ferreiro-Pantín, Pablo Conesa-Zamora, José Ramón Antúnez-López, Masahito Kawazu, Manel Esteller, Claus Lindbjerg Andersen, Jose M.C. Tubio, Rafael López-López, Juan Ruiz-Bañobre

Publikováno v: iScience, Vol 26, Iss 3, Pp 106127- (2023)

Summary: Deficiency in DNA MMR activity results in tumors with a hypermutator phenotype, termed microsatellite instability (MSI). Beyond its utility in Lynch syndrome screening algorithms, today MSI has gained importance as predictive biomarker for v

Externí odkaz: https://doaj.org/article/83da6a3eac0640c8b90364fbec5aee49

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Akademický článek

Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy

Autor: Martín Pérez-Martelo, Alejandro González-García, Yolanda Vidal-Ínsua, Cristina Blanco-Freire, Elena María Brozos-Vázquez, Ihab Abdulkader-Nallib, Javier Álvarez-Fernández, Héctor Lázare-Iglesias, Carolina García-Martínez, Yoel Z. Betancor, María Sánchez-Ares, Jose M. C. Tubío, Francisca Vázquez-Rivera, Sonia Candamio-Folgar, Rafael López-López, Juan Ruiz-Bañobre

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract Pan-Immune-Inflammation Value (PIV) has been recently proposed as a new blood-based prognostic biomarker in metastatic colorectal cancer (mCRC). Herein we aimed to validate its prognostic significance and to evaluate its utility for disease

Externí odkaz: https://doaj.org/article/6fcad864ced14279bf0e7a32953f76b3

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Akademický článek

3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease

Autor: Iria Seoane-Viaño, Noemí Gómez-Lado, Héctor Lázare-Iglesias, Xurxo García-Otero, José Ramón Antúnez-López, Álvaro Ruibal, Juan Jesús Varela-Correa, Pablo Aguiar, Abdul W. Basit, Francisco J. Otero-Espinar, Miguel González-Barcia, Alvaro Goyanes, Asteria Luzardo-Álvarez, Anxo Fernández-Ferreiro

Publikováno v: Biomedicines, Vol 8, Iss 12, p 563 (2020)

The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel disease. Blends of Gelucire

Externí odkaz: https://doaj.org/article/c822ff86ea464786b418913444786d10

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Jaundice in relation to immune activation during Epstein-Barr virus-induced infectious mononucleosis

Autor: Emilio-Manuel Páez-Guillán, Joaquín Campos-Franco, Rosario Alende, Héctor Lázare, Carmen Beceiro, Arturo Gonzalez-Quintela

Publikováno v: The American Journal of the Medical Sciences. 365:270-278

Liver involvement during infectious mononucleosis is common, but jaundice is considered rare. This study aimed to investigate serum bilirubin concentrations in patients with infectious mononucleosis and immune abnormalities associated with jaundice.W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af190cc395bb28e7d9c18553c62ad1e
https://doi.org/10.1016/j.amjms.2022.12.004

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MSIMEP:Predicting microsatellite instability from microarray DNA methylation tumor profiles

Publikováno v: Santamarina-García, M, Brea-Iglesias, J, Bramsen, J B, Fuentes-Losada, M, Caneiro-Gómez, F J, Vázquez-Bueno, J Á, Lázare-Iglesias, H, Fernández-Díaz, N, Sánchez-Rivadulla, L, Betancor, Y Z, Ferreiro-Pantín, M, Conesa-Zamora, P, Antúnez-López, J R, Kawazu, M, Esteller, M, Andersen, C L, Tubio, J M C, López-López, R & Ruiz-Bañobre, J 2023, ' MSIMEP : Predicting microsatellite instability from microarray DNA methylation tumor profiles ', iScience, vol. 26, no. 3, 106127 . https://doi.org/10.1016/j.isci.2023.106127

Deficiency in DNA MMR activity results in tumors with a hypermutator phenotype, termed microsatellite instability (MSI). Beyond its utility in Lynch syndrome screening algorithms, today MSI has gained importance as predictive biomarker for various an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959382c34f73d9353e0140c44bcbc8f0
https://pure.au.dk/portal/da/publications/msimep(cee2a8c5-cfe7-4870-9413-6ff85f962a41).html

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