Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Héctor G. Palmer"'
Autor:
Estefania Cuesta-Borràs, Cándida Salvans, Oriol Arqués, Irene Chicote, Lorena Ramírez, Laia Cabellos, Jordi Martínez-Quintanilla, Alex Mur-Espinosa, Alejandro García-Álvarez, Jorge Hernando, Juan Ramón Tejedor, Oriol Mirallas, Elena Élez, Mario F. Fraga, Josep Tabernero, Paolo Nuciforo, Jaume Capdevila, Héctor G. Palmer, Isabel Puig
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112927- (2023)
Summary: Tumor relapse is linked to rapid chemoresistance and represents a bottleneck for cancer therapy success. Engagement of a reduced proliferation state is a non-mutational mechanism exploited by cancer cells to bypass therapy-induced cell death
Externí odkaz:
https://doaj.org/article/ffddfe7e78e24b41b3ac5cdc84b543de
Autor:
Pier Selenica, Nitya Raj, Rahul Kumar, David N. Brown, Oriol Arqués, Diane Reidy, David Klimstra, Matija Snuderl, Jonathan Serrano, Héctor G. Palmer, Britta Weigelt, Jorge S. Reis‐Filho, Maurizio Scaltriti
Publikováno v:
Molecular Oncology, Vol 13, Iss 8, Pp 1684-1692 (2019)
Solid pseudopapillary neoplasms (SPNs) are rare and relatively indolent tumors of the pancreas. While primary SPNs can be surgically resected, there are currently no therapies available for patients with advanced stage disease. Given that these tumor
Externí odkaz:
https://doaj.org/article/6576b5b9ce9942dd85b2e2e07c950d78
Autor:
Héctor G. Palmer, Santiago Rojas, Josep Tabernero, Ana Vivancos, Guillem Argilés, Maria Elena Elez, Aleix Prat, Eloy Espín, Ramón Charco, Debora Moreno, Leire Mendizabal, Helena Allende, Karina Caci, Stefania Landolfi, José Jimenez, Juan D. Gispert, José Raúl Herance, Oriol Arqués, Stephan P. Tenbaum, Irene Chicote, Isabel Puig
PDF file - 674K, Histological characterization of patients' carcinomas and the correspondent xenograft tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ad7323d75cd2d59662475afff2dadb
https://doi.org/10.1158/1078-0432.22446470
https://doi.org/10.1158/1078-0432.22446470
Autor:
Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués
Supplementary Figures S1-S11. Figure S1. Apoptosis of CRC patient-derived cells upon treatment with API-2 or NVP-BKM120 in combination with XAV939. Figure S2. Evaluation of apoptosis in primary sphere cell cultures by immunofluorescent quantification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ee44151d396e2fbb1c11131f27edc4
https://doi.org/10.1158/1078-0432.22460681.v1
https://doi.org/10.1158/1078-0432.22460681.v1
Autor:
Violeta Serra, José Baselga, Maurizio Scaltriti, Josep Tabernero, Héctor G. Palmer, Irene Chicote, Ana Vivancos, Judit Matito, Livio Trusolino, Andrea Bertotti, Rodrigo Dienstmann, Guillem Argilés, Katti Jessen, Paolo Nuciforo, Claudia Aura, Marta Guzmán, Pilar Antón, Judit Grueso, Olga Rodríguez, Albert Gris-Oliver, María Teresa Calvo, Yasir H. Ibrahim, Martín A. Rivas, Celina García-García
Purpose: PI3K pathway activation occurs in concomitance with RAS/BRAF mutations in colorectal cancer, limiting the sensitivity to targeted therapies. Several clinical studies are being conducted to test the tolerability and clinical activity of dual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490a80d2611f304a861eaa7aed9ae5af
https://doi.org/10.1158/1078-0432.c.6524721.v1
https://doi.org/10.1158/1078-0432.c.6524721.v1
Autor:
Héctor G. Palmer, Santiago Rojas, Josep Tabernero, Ana Vivancos, Guillem Argilés, Maria Elena Elez, Aleix Prat, Eloy Espín, Ramón Charco, Debora Moreno, Leire Mendizabal, Helena Allende, Karina Caci, Stefania Landolfi, José Jimenez, Juan D. Gispert, José Raúl Herance, Oriol Arqués, Stephan P. Tenbaum, Irene Chicote, Isabel Puig
PDF file - 115K, 18-FDG is the best radiotracer for tumor growth evaluation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b530a533c0a0fd81b6fd0515525590
https://doi.org/10.1158/1078-0432.22446461.v1
https://doi.org/10.1158/1078-0432.22446461.v1
Autor:
Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués
Supplementary Tables S1-S15. Table S1. Genes and positions analyzed by amplicon sequencing. Table S2. Genes sequenced by Haloplex Target Enrichment System. Table S3. Antibodies. Table S4. Treatment-induced apoptosis in 10 primary patient-derived sphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cf6897db7daa06de70b36622bd3eb7
https://doi.org/10.1158/1078-0432.22460678.v1
https://doi.org/10.1158/1078-0432.22460678.v1
Autor:
Violeta Serra, José Baselga, Maurizio Scaltriti, Josep Tabernero, Héctor G. Palmer, Irene Chicote, Ana Vivancos, Judit Matito, Livio Trusolino, Andrea Bertotti, Rodrigo Dienstmann, Guillem Argilés, Katti Jessen, Paolo Nuciforo, Claudia Aura, Marta Guzmán, Pilar Antón, Judit Grueso, Olga Rodríguez, Albert Gris-Oliver, María Teresa Calvo, Yasir H. Ibrahim, Martín A. Rivas, Celina García-García
Table S1. MiSeq 57-gene panel list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecbc6642170b1d5d5737e7985dae14e
https://doi.org/10.1158/1078-0432.22461213
https://doi.org/10.1158/1078-0432.22461213
Autor:
Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués
Purpose: Oncogenic mutations in the KRAS/PI3K/AKT pathway are one of the most frequent alterations in cancer. Although PI3K or AKT inhibitors show promising results in clinical trials, drug resistance frequently emerges. We previously revealed Wnt/β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1981c98cbf41f842336ba904dddad422
https://doi.org/10.1158/1078-0432.c.6524564.v1
https://doi.org/10.1158/1078-0432.c.6524564.v1
Autor:
Babita Madan, David M. Virshup, Enrico Petretto, Héctor G. Palmer, Oriol Arqués, Jun Yi Stanley Lim, Nathan Harmston
Supplementary Figures 1 and 2 and legends for Table S1, S2 and S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e838a8e85064aeaae82ee876d71b9e
https://doi.org/10.1158/0008-5472.22426750.v1
https://doi.org/10.1158/0008-5472.22426750.v1