European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases

Autor: Arthur A. M. Wilde, Christopher Semsarian, Manlio F. Márquez, Alireza Sepehri Shamloo, Michael J. Ackerman, Euan A. Ashley, Back Sternick Eduardo, Héctor Barajas‐Martinez, Elijah R. Behr, Connie R. Bezzina, Jeroen Breckpot, Philippe Charron, Priya Chockalingam, Lia Crotti, Michael H. Gollob, Steven Lubitz, Naomasa Makita, Seiko Ohno, Martín Ortiz‐Genga, Luciana Sacilotto, Eric Schulze‐Bahr, Wataru Shimizu, Nona Sotoodehnia, Rafik Tadros, James S. Ware, David S. Winlaw, Elizabeth S. Kaufman, Takeshi Aiba, Andreas Bollmann, Jong‐Il Choi, Aarti Dalal, Francisco Darrieux, John Giudicessi, Mariana Guerchicoff, Kui Hong, Andrew D. Krahn, Ciorsti Mac Intyre, Judith A. Mackall, Lluís Mont, Carlo Napolitano, Pablo Ochoa Juan, Petr Peichl, Alexandre C. Pereira, Peter J. Schwartz, Jon Skinner, Christoph Stellbrink, Jacob Tfelt‐Hansen, Thomas Deneke

Publikováno v: Journal of Arrhythmia, Vol 38, Iss 4, Pp 491-553 (2022)

Externí odkaz: https://doaj.org/article/065b869d10df4d35a27b0f57e20fcc2b

Acquired Long QT Syndrome and Torsades de Pointes after Mitral Valve Replacement Surgery

Autor: Carlos Rodríguez-Artuza, Héctor Barajas, José Rivera, Emilio Clavel, Mayela Labarca

Publikováno v: Journal of Cardiac Arrhythmias, Vol 34, Iss 2 (2021)

Acquired long QT syndrome (aLQTS) can occur in up to one third of patients undergoing cardiac surgery and is often undisclosed. We present a case of a 55-year-old male patient admitted to our center for mitral valve replacement surgery, and, during t

Externí odkaz: https://doaj.org/article/2a4953ddf5e540939a005ed1cb8d8ab3

Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

Autor: Michael Xavier Doss, José M Di Diego, Robert J Goodrow, Yuesheng Wu, Jonathan M Cordeiro, Vladislav V Nesterenko, Héctor Barajas-Martínez, Dan Hu, Janire Urrutia, Mayurika Desai, Jacqueline A Treat, Agapios Sachinidis, Charles Antzelevitch

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40288 (2012)

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study exa

Externí odkaz: https://doaj.org/article/37d1fac9f03c47c1950714ea3f4d6f80

A Carvedilol Analogue, VKII-86, Prevents Hypokalaemia- induced Ventricular Arrhythmia through Novel multi-Channel Effects

Autor: Victoria M. Robinson, Izzeddin Alsalahat, Sally Freeman, Charles Antzelevitch, Héctor Barajas‐Martinez, Luigi Venetucci

Publikováno v: Robinson, V, Alsalahat, I, Freeman, S, Antzelevitch, C, Barajas-Martinez, H & Venetucci, L 2022, ' A Carvedilol Analogue, VKII-86, Prevents Hypokalaemia-induced Ventricular Arrhythmia through Novel multi-Channel Effects. ', British Journal of Pharmacology, vol. 179, no. 11, pp. 2713-2732 . https://doi.org/10.1111/bph.15775

Background and Purpose: QT prolongation and intracellular Ca 2+ loading with diastolic Ca 2+ release via ryanodine receptors (RyR2) are the predominant mechanisms underlying hypokalaemia-induced ventricular arrhythmia. We investigated the antiarrhyth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8bdbbd9386c605a599bf23272680fc
https://research.manchester.ac.uk/en/publications/64a3e33b-abf4-47a5-92ac-f167ef39cbbb

Expression of Hv1 proton channels in myeloid-derived suppressor cells (MDSC) and its potential role in T cell regulation

Autor: Juan J. Alvear-Arias, Christian Carrillo, Javiera Paz Villar, Richard Garcia-Betancourt, Antonio Peña-Pichicoi, Audry Fernandez, Miguel Fernandez, Emerson M. Carmona, Amaury Pupo, Alan Neely, Osvaldo Alvarez, Jose Garate, Héctor Barajas-Martinez, H. Peter Larsson, Angélica Lopez-Rodriguez, Ramon Latorre, Carlos Gonzalez

Publikováno v: Proceedings of the National Academy of Sciences. 119

SignificanceImmunosuppression by myeloid-derived suppressor cells (MDSC), especially near tumor surfaces, involves the extracellular production of reactive oxygen species (ROS). ROS generation in MDSC occurs during the oxidation of NADPH to NADP+, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5793e0b083b6a0cf007c660e5167172
https://doi.org/10.1073/pnas.2104453119