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Autor:
Håkon Kirkeby Buch, Robert S. Hagan, Michelle G. Meier, Jagesh V. Shah, Patrick Meraldi, Michael S. Manak, Peter K. Sorger
Publikováno v:
Molecular Biology of the Cell, 22 (22)
Molecular Biology of the Cell
Molecular Biology of the Cell, Vol. 22, No 22 (2011) pp. 4236-46
Molecular Biology of the Cell
Molecular Biology of the Cell, Vol. 22, No 22 (2011) pp. 4236-46
The spindle assembly checkpoint links the onset of anaphase to completion of chromosome-microtubule attachment and is mediated by the binding of Mad and Bub proteins to kinetochores of unattached or maloriented chromosomes. Mad2 and BubR1 traffic bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b3123c1e80770c93b894a1557a9dd6
https://hdl.handle.net/20.500.11850/40677
https://hdl.handle.net/20.500.11850/40677
Publikováno v:
Nature biotechnology. 29(3)
A gathering of biotech leaders in Sweden attempts to share candid opinions on the most successful strategies for building a biotech in Europe.
Autor:
John Maciejowski, Jennifer Corona, Jagesh V. Shah, Masato T. Kanemaki, Philippe Collin, Håkon Kirkeby Buch, Veronica Rodriguez-Bravo, Prasad V. Jallepalli
Publikováno v:
Cell. (5):1017-1031
SummaryThe spindle assembly checkpoint (SAC) delays anaphase until all chromosomes are bioriented on the mitotic spindle. Under current models, unattached kinetochores transduce the SAC by catalyzing the intramitotic production of a diffusible inhibi