Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Håkan Ottosson"'
Autor:
Iwona T. Myszor, Zahida Parveen, Håkan Ottosson, Peter Bergman, Birgitta Agerberth, Roger Strömberg, Gudmundur H. Gudmundsson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at defining the response and signali
Externí odkaz:
https://doaj.org/article/c34430d9332c4c8481c652a6656d4119
Autor:
Håkan Ottosson, Manuel Valiente, Roberto Boada, Wenyi Zheng, Rui He, Ying Zhao, Tobias Ginman, Moustapha Hassan, Maria Angels Subirana
Publikováno v:
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Selenocompounds (SeCs) are promising therapeutic agents for a wide range of diseases including cancer. The treatment results are heterogeneous and dependent on both the chemical species and the concentration of SeCs. Moreover, the mechanisms of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eecb9eff28989c89740b3e91923f831
https://ddd.uab.cat/record/252416
https://ddd.uab.cat/record/252416
Autor:
Wenyi Zheng, Ying Zhao, Tobias Ginman, Håkan Ottosson, Rui He, Svante Norgren, Moustapha Hassan
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 143
N-acetylcysteine amide (NACA) is the amide derivative of N-acetylcysteine (NAC) that is rapidly converted to NAC after systemic administration. It has emerged as a promising thiol antioxidant for multiple indications; however, the pharmacokinetic pro
Autor:
Birgitta Agerberth, Peter Bergman, Roger Strömberg, Iwona T Myszor, Zahida Parveen, Gudmundur H. Gudmundsson, Håkan Ottosson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Publisher's version (útgefin grein)
Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at
Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at
Autor:
Fadwa Benkessou, Maria Angels Subirana, Wenyi Zheng, Manuchehr Abedi-Valugerdi, Moustapha Hassan, Brigitte Twelkmeyer, Håkan Ottosson, Tobias Ginman, Ying Zhao, Siyao Wang
Publikováno v:
Analytical chemistry. 89(14)
p-Xyleneselenocyanate (p-XSC) is one of the most investigated selenium compounds in cancer-prevention and -therapy. Despite the potent anticancer property, there is still no proper method to perform the quantitative analysis of p-XSC in plasma. In th
Autor:
Erica Miraglia, Håkan Ottosson, Frank Nylén, Gudmundur H. Gudmundsson, Roger Strömberg, Andreas Cederlund, Birgitta Agerberth
Publikováno v:
Innate Immunity. 20:364-376
Innate immunity, the front line of our defence against pathogens, relies, to a great extent, on the production of antimicrobial peptides (AMPs). These peptides exhibit antimicrobial activity and immunomodulatory properties. In humans, AMPs include th
Autor:
Roger Strömberg, Erica Miraglia, Birgitta Agerberth, Protim Sarker, Frank Nylén, Gudmundur H. Gudmundsson, Peter Bergman, Håkan Ottosson, Rubhana Raqib
Publikováno v:
Scientific Reports
A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vi
Autor:
Erica Miraglia, Frank Nylén, Birgitta Agerberth, Susan Farmand, Gudmundur H. Gudmundsson, Peter Bergman, Håkan Ottosson, Elias S.J. Arnér, Roger Strömberg, Katarina Johansson, Marcus Cebula
Publikováno v:
Scientific Reports
Bacterial resistance against classical antibiotics is a growing problem and the development of new antibiotics is limited. Thus, novel alternatives to antibiotics are warranted. Antimicrobial peptides (AMPs) are effector molecules of innate immunity
Autor:
J. R. Merritt, Zufan Wu, C. S. Rao, Uko E. Udodong, Håkan Ottosson, Carmichael S. Roberts, Bert Fraser-Reid, Robert Madsen
Publikováno v:
ChemInform. 24
Autor:
Håkan Ottosson, C. Srinivas Rao, J. Robert Merritt, Uko E. Udodong, Bert Fraser-Reid, Robert Madsen, Zufan Wu, Carmichael Roberts
Publikováno v:
Synlett. 1992:927-942