Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors.

Autor: Pekkarinen M; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Nordfors K; Tampere Center for Child Health Research, Tays Cancer Center, Tampere University and Tampere University Hospital, Tampere, Finland.; Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Unit of Pediatric Hematology and Oncology, Tampere University Hospital, Tampere, Finland., Uusi-Mäkelä J; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Kytölä V; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Hartewig A; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Huhtala L; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Rauhala M; Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Department of Neurosurgery, Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland., Urhonen H; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Häyrynen S; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Afyounian E; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Yli-Harja O; Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Institute for Systems Biology, Seattle, WA, USA., Zhang W; Cancer Genomics and Precision Oncology, Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA., Helen P; Department of Neurosurgery, Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland., Lohi O; Tampere Center for Child Health Research, Tays Cancer Center, Tampere University and Tampere University Hospital, Tampere, Finland.; Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Haapasalo H; Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Fimlab Laboratories Ltd, Tampere University Hospital, Tampere, Finland., Haapasalo J; Tays Cancer Center, Tampere University Hospital, Tampere, Finland.; Department of Neurosurgery, Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland.; Fimlab Laboratories Ltd, Tampere University Hospital, Tampere, Finland., Nykter M; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Kesseli J; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland., Rautajoki KJ; Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland kirsi.rautajoki@tuni.fi.; Tampere Institute for Advanced Study, Tampere University, Tampere, Finland.

Publikováno v: Life science alliance [Life Sci Alliance] 2024 Mar 18; Vol. 7 (6). Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).

CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel.

Autor: Ramste M; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Ritvos M; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Häyrynen S; Veracell Oy, Tampere, Finland., Kiiski JI; Department of Clinical Pharmacology and Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Niemi M; Department of Clinical Pharmacology and Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland., Sinisalo J; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2023 Oct; Vol. 16 (10), pp. 2010-2020. Date of Electronic Publication: 2023 Aug 16.

Emerging Signatures of Hematological Malignancies from Gene Expression and Transcription Factor-Gene Regulations.

Autor: Dall'Olio, Daniele¹ (AUTHOR), Magnani, Federico¹ (AUTHOR), Casadei, Francesco² (AUTHOR), Matteuzzi, Tommaso³ (AUTHOR), Curti, Nico⁴ (AUTHOR), Merlotti, Alessandra⁴ (AUTHOR), Simonetti, Giorgia⁵ (AUTHOR), Della Porta, Matteo Giovanni⁶ (AUTHOR), Remondini, Daniel⁴ (AUTHOR), Tarozzi, Martina^1,7 (AUTHOR), Castellani, Gastone^1,7 (AUTHOR) gastone.castellani@unibo.it

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13588. 16p.

Clinical Significance and Patterns of Potential Drug–Drug Interactions in Cardiovascular Patients: Focus on Low-Dose Aspirin and Angiotensin-Converting Enzyme Inhibitors.

Autor: Anfinogenova, Nina D.¹ (AUTHOR) cardio.intl@gmail.com, Stepanov, Vadim A.² (AUTHOR), Chernyavsky, Alexander M.³ (AUTHOR), Karpov, Rostislav S.¹ (AUTHOR), Efimova, Elena V.¹ (AUTHOR), Novikova, Oksana M.¹ (AUTHOR), Trubacheva, Irina A.¹ (AUTHOR), Falkovskaya, Alla Y.¹ (AUTHOR), Maksimova, Aleksandra S.¹ (AUTHOR), Ryumshina, Nadezhda I.¹ (AUTHOR), Shelkovnikova, Tatiana A.¹ (AUTHOR), Ussov, Wladimir Y.^1,3 (AUTHOR), Vaizova, Olga E.⁴ (AUTHOR), Popov, Sergey V.¹ (AUTHOR), Repin, Alexei N.¹ (AUTHOR)

Publikováno v: Journal of Clinical Medicine. Aug2024, Vol. 13 Issue 15, p4289. 21p.

Data-driven characterization of molecular phenotypes across heterogeneous sample collections.

Autor: Mehtonen J; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland., Pölönen P; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland., Häyrynen S; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Dufva O; Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Lin J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Liuksiala T; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Tampere Center for Child Health Research, Tampere University and Tampere University Hospital, Tampere, Finland., Granberg K; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lohi O; Tampere Center for Child Health Research, Tampere University and Tampere University Hospital, Tampere, Finland., Hautamäki V; School of Computing, University of Eastern Finland, Joensuu, Finland., Nykter M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Heinäniemi M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2019 Jul 26; Vol. 47 (13), pp. e76.