Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.

Autor: Hofmann A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Häsler LM; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Lambert M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Kaeser SA; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Gräber-Sultan S; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Obermüller U; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Kuder-Buletta E; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., la Fougere C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Vöglein J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig Maximilians-Universität München, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Levin J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig Maximilians-Universität München, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Fox NC; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Ryan NS; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Zetterberg H; Department Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Llibre-Guerra JJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Perrin RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Ibanez L; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Schofield PR; Neuroscience Research Australia, Randwick, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia., Brooks WS; Neuroscience Research Australia, Randwick, NSW, Australia.; School of Clinical Medicine, Faculty of Medicine and Health Sydney, University of New South Wales, Sydney, Australia., Day GS; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL, USA., Farlow MR; Indiana Alzheimer Disease Center and Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Allegri RF; Instituto Neurológico FLENI, Buenos Aires, Argentina., Chrem Mendez P; Instituto Neurológico FLENI, Buenos Aires, Argentina., Ikeuchi T; Brain Research Institute, Niigata University, Niigata, Japan., Kasuga K; Brain Research Institute, Niigata University, Niigata, Japan., Lee JH; Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Roh JH; Departments of Neurology and Physiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, South Korea., Mori H; Faculty of Medicine, Osaka Metropolitan University, Nagaoka Sutoku University, Osaka, Japan., Lopera F; Grupo de Neurociencias de Antioquia (GNA), Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia., Bateman RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., McDade E; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Gordon BA; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Chhatwal JP; Department of Neurology, Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Brigham and Women's Hospital Boston, Boston, MA, USA., Jucker M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. mathias.jucker@uni-tuebingen.de.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. mathias.jucker@uni-tuebingen.de., Schultz SA; Department of Neurology, Harvard Medical School, Boston, MA, USA. saschultz@mgh.harvard.edu.; Massachusetts General Hospital, Boston, MA, USA. saschultz@mgh.harvard.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 18; Vol. 15 (1), pp. 9982. Date of Electronic Publication: 2024 Nov 18.

Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.

Autor: Wagner J; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Degenhardt K; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Veit M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Louros N; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Konstantoulea K; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Skodras A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Wild K; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Liu P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Obermüller U; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Bansal V; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Dalmia A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Häsler LM; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Lambert M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., De Vleeschouwer M; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Davies HA; Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.; Liverpool Centre for Cardiovascular Sciences, University of Liverpool, Liverpool, UK., Madine J; Liverpool Centre for Cardiovascular Sciences, University of Liverpool, Liverpool, UK.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Kronenberg-Versteeg D; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Feederle R; Monoclonal Antibody Core Facility, Institute for Diabetes and Obesity, Helmholtz Zentrum München, Research Center for Environmental Health, Neuherberg, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Del Turco D; Institute of Clinical Neuroanatomy, Dr. Senckenberg Anatomy, Neuroscience Center, Goethe University, Frankfurt/Main, Germany., Nilsson KPR; Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden., Lashley T; Queen Square Brain Bank for Neurological Disorders, University College London Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, UK., Deller T; Institute of Clinical Neuroanatomy, Dr. Senckenberg Anatomy, Neuroscience Center, Goethe University, Frankfurt/Main, Germany., Gearing M; Department of Pathology and Laboratory Medicine and Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA., Walker LC; Department of Neurology and Emory National Primate Research Center, Emory University, Atlanta, GA, USA., Heutink P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Rousseau F; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Schymkowitz J; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Jucker M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Neher JJ; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. jonas.neher@dzne.de.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. jonas.neher@dzne.de.

Publikováno v: Nature [Nature] 2022 Dec; Vol. 612 (7938), pp. 123-131. Date of Electronic Publication: 2022 Nov 16.

Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease.

Autor: Brosseron F; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Maass A; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany., Kleineidam L; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Ravichandran KA; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., González PG; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., McManus RM; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Ising C; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Santarelli F; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Kolbe CC; University of Bonn Medical Center, Institute of Innate Immune, Venusberg-Campus 1, 53127 Bonn, Germany., Häsler LM; Hertie Institute for Clinical Brain Research, Department of Cellular Neurology, University of Tübingen, Otfried-Müller-Strasse 27, 72076 Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany., Wolfsgruber S; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Marquié M; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Boada M; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Orellana A; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., de Rojas I; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Röske S; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Cosma NC; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Cetindag A; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Wang X; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany; Department of Psychiatry and Psychotherapy, Technical University Munich, 81675 Munich, Germany., Spruth EJ; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Altenstein S; German Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin 10117, Germany; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117 Berlin, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Fliessbach K; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Wiltfang J; German Center for Neurodegenerative Diseases (DZNE), Von-Siebold-Str. 3a, Göttingen 37075, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Str. 5, 37075 Göttingen, Germany; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal., Schott BH; German Center for Neurodegenerative Diseases (DZNE), Von-Siebold-Str. 3a, Göttingen 37075, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Str. 5, 37075 Göttingen, Germany; Leibniz Institute for Neurobiology, Brenneckestr. 6, 39118 Magdeburg, Germany., Bürger K; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich 81377, Germany; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, 81377 Munich, Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, 81377 Munich, Germany., Dichgans M; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich 81377, Germany; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, 81377 Munich, Germany., Perneczky R; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich 81377, Germany; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, London, UK., Rauchmann BS; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, 81377 Munich, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Str. 20, Rostock 18147, Germany; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, 18147 Rostock, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Str. 20, Rostock 18147, Germany; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, 18147 Rostock, Germany., Goerss D; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, 18147 Rostock, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Munk MH; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Yakupov R; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany., Dobisch L; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Metzger CD; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany; Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, Magdeburg, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Leipziger Straße 44, Magdeburg 39120, Germany., Ewers M; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich 81377, Germany., Dechent P; MR-Research in Neurosciences, Department of Cognitive Neurology, Georg-August-University Göttingen, Göttingen, Germany., Haynes JD; Bernstein Center for Computational Neurosciences, Charité - Universitätsmedizin, Berlin, Germany., Scheffler K; Department for Biomedical Magnetic Resonance, University of Tübingen, 72076 Tübingen, Germany., Roy N; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany., Rostamzadeh A; Department of Psychiatry, University of Cologne, Medical Faculty, Kerpener Strasse 62, 50924 Cologne, Germany., Teunissen CE; Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam University Medical centers, Vrije Universiteit, Amsterdam, the Netherlands., Marchant NL; Division of Psychiatry, University College London, London, UK., Spottke A; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurology, University of Bonn, Venusberg-Campus 1, 53127 Bonn, Germany., Jucker M; Hertie Institute for Clinical Brain Research, Department of Cellular Neurology, University of Tübingen, Otfried-Müller-Strasse 27, 72076 Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany., Latz E; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; University of Bonn Medical Center, Institute of Innate Immune, Venusberg-Campus 1, 53127 Bonn, Germany., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany., Mengel D; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany; Division Translational Genomics of Neurodegenerative Diseases, Center for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, Otfried-Müller-Strasse 27, 72076 Tübingen, Germany., Synofzik M; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 27, Tübingen 72076, Germany; Division Translational Genomics of Neurodegenerative Diseases, Center for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, Otfried-Müller-Strasse 27, 72076 Tübingen, Germany., Jessen F; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Psychiatry, University of Cologne, Medical Faculty, Kerpener Strasse 62, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany., Ramirez A; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA., Ruiz A; Research Center and Memory Clinic, Fundacío ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Heneka MT; German Center for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn 53127, Germany; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn Medical Center, Venusberg-Campus 1, 53127 Bonn, Germany; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, 4362 Esch-sur- Alzette, Luxembourg; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, 55 Lake Avenue, North Worcester, Massachusetts 01655, USA. Electronic address: michael.heneka@uni.lu.

Publikováno v: Neuron [Neuron] 2022 Mar 16; Vol. 110 (6), pp. 1009-1022.e4. Date of Electronic Publication: 2022 Jan 06.

Cerebrospinal fluid cytokine levels are associated with macrophage infiltration into tumor tissues of glioma patients.

Autor: Kemmerer CL; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany., Schittenhelm J; Department of Pathology and Neuropathology, University Hospital Tübingen, Calwerstr. 3, Tübingen, Germany.; Center for Neuro-Oncology, Comprehensive Cancer Center Tuebingen-Stuttgart, University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, Tübingen, Germany.; German Cancer Consortium (DKTK), DKFZ partner site Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany., Dubois E; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany., Neumann L; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany., Häsler LM; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, Germany., Lambert M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, Germany., Renovanz M; Center for Neuro-Oncology, Comprehensive Cancer Center Tuebingen-Stuttgart, University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, Tübingen, Germany.; Department of Neurology and Interdisciplinary Neuro-Oncology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany.; Department of Neurosurgery, University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Kaeser SA; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, Germany., Tabatabai G; Center for Neuro-Oncology, Comprehensive Cancer Center Tuebingen-Stuttgart, University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, Tübingen, Germany.; German Cancer Consortium (DKTK), DKFZ partner site Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.; Department of Neurology and Interdisciplinary Neuro-Oncology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany., Ziemann U; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany.; Department of Neurology & Stroke, Eberhard-Karls University Tübingen, Tübingen, Germany., Naumann U; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany., Kowarik MC; Department of Vascular Neurology, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Otfried-Müller-Straße 27, Tübingen, Germany. markus.kowarik@uni-tuebingen.de.; Department of Neurology & Stroke, Eberhard-Karls University Tübingen, Tübingen, Germany. markus.kowarik@uni-tuebingen.de.; Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, Munich, Germany. markus.kowarik@uni-tuebingen.de.

Publikováno v: BMC cancer [BMC Cancer] 2021 Oct 15; Vol. 21 (1), pp. 1108. Date of Electronic Publication: 2021 Oct 15.

Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures.

Autor: Barth M; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Graduate Training Center of Neuroscience, University of Tuebingen, 72076, Tuebingen, Germany., Bacioglu M; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Graduate Training Center of Neuroscience, University of Tuebingen, 72076, Tuebingen, Germany., Schwarz N; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Novotny R; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Brandes J; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Welzer M; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Graduate Training Center of Neuroscience, University of Tuebingen, 72076, Tuebingen, Germany., Mazzitelli S; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Häsler LM; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Schweighauser M; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Wuttke TV; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Department of Neurosurgery, University of Tuebingen, 72076, Tuebingen, Germany., Kronenberg-Versteeg D; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Fog K; Division of Neuroscience, H. Lundbeck A/S, 2500, Valby, Denmark., Ambjørn M; Division of Neuroscience, H. Lundbeck A/S, 2500, Valby, Denmark., Alik A; MIRCen, CEA and Laboratory of Neurodegenerative Diseases, CNRS, Institut François Jacob, 92265, Fontenay-aux-Roses, France., Melki R; MIRCen, CEA and Laboratory of Neurodegenerative Diseases, CNRS, Institut François Jacob, 92265, Fontenay-aux-Roses, France., Kahle PJ; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany.; Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie-Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany., Shimshek DR; Neuroscience Research, Novartis Institutes for BioMedical Research, CH-4056, Basel, Switzerland., Koch H; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.; Department of Epileptology, Neurology, RWTH Aachen University, Aachen, Germany., Jucker M; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany. mathias.jucker@uni-tuebingen.de.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany. mathias.jucker@uni-tuebingen.de., Tanriöver G; DZNE, German Center for Neurodegenerative Diseases, 72076, Tuebingen, Germany. gaye.tanrioever@uni-tuebingen.de.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany. gaye.tanrioever@uni-tuebingen.de.

Publikováno v: Molecular neurodegeneration [Mol Neurodegener] 2021 Aug 11; Vol. 16 (1), pp. 54. Date of Electronic Publication: 2021 Aug 11.