Kinetic study of aza-amino acid incorporation into peptide chains: Influence of the steric effect of the side chain

Autor: Härk, Heleri Heike, Troska, Alla, Arujõe, Meeli, Burk, Peeter, Järv, Jaak, Ploom, Anu

Publikováno v: In Tetrahedron 17 December 2022 129

The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue.

Autor: Porosk, Ly¹ (AUTHOR), Härk, Heleri Heike¹ (AUTHOR), Arukuusk, Piret^1,2 (AUTHOR), Haljasorg, Uku³ (AUTHOR), Peterson, Pärt³ (AUTHOR), Kurrikoff, Kaido^1,2 (AUTHOR) kaido.kurrikoff@ut.ee

Publikováno v: Pharmaceutics. Mar2023, Vol. 15 Issue 3, p952. 14p.

Enhancing Cellular Uptake of Native Proteins through Bio-Orthogonal Conjugation with Chemically Synthesized Cell-Penetrating Peptides.

Autor: Nebogatova, Jekaterina, Porosk, Ly, Härk, Heleri Heike, Kurrikoff, Kaido

Publikováno v: Pharmaceutics; May2024, Vol. 16 Issue 5, p617, 14p

Asa-peptiidsideme moodustumine aktivaatoriga trifosgeen

Autor: Härk, Heleri Heike

Peptiidid on head ravimikandidaadid, kuid nende kasutamine ravimitena on piiratud kiire lagunemise tõttu elusorganismides. Seega on arendatud peptidomimeetikuid, nt asa-peptiide, mis oleksid ensümaatilisele degradatsioonile vastupidavamad. Asa-pept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1018::9cc150064082455cf3cb38f791b68cfc
http://hdl.handle.net/10062/61050

Utilization of Cell-Penetrating Peptides for In Vivo Delivery of Bioactive Cargo: The Effect of Nanoparticle Formulation.

Autor: Arukuusk P; Institute of Technology, University of Tartu, Tartu, Estonia. piret.arukuusk@ut.ee., Härk HH; Institute of Technology, University of Tartu, Tartu, Estonia., Langel Ü; Institute of Technology, University of Tartu, Tartu, Estonia.; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2383, pp. 247-253.