Zobrazeno 1 - 10
of 90
pro vyhledávání: '"H, van der Weide"'
Autor:
Judith H. I. Haarhuis, Robin H. van der Weide, Vincent A. Blomen, Koen D. Flach, Hans Teunissen, Laureen Willems, Thijn R. Brummelkamp, Benjamin D. Rowland, Elzo de Wit
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The link between 3D genome architecture and gene expression is still far from resolved. Here the authors show that loss of the CDK catalytic subunit of the Mediator complex results in heterochromatic silencing, which can be rescued by stabilization o
Externí odkaz:
https://doaj.org/article/ec4e2c2fb27a4c92a19bfc6346c64a97
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 1-10.e4 (2018)
Summary: The spatial organization of chromosomes is critical in establishing gene expression programs. We generated in situ Hi-C maps throughout zebrafish development to gain insight into higher-order chromatin organization and dynamics. Zebrafish ch
Externí odkaz:
https://doaj.org/article/a6728150b3b24193bbd046936716d29a
Autor:
Silke J.A. Lochs, Robin H. van der Weide, Kim L. de Luca, Tessy Korthout, Ramada E. van Beek, Hiroshi Kimura, Jop Kind
Gene expression programs result from the collective activity of many regulatory factors. To obtain insight into the mechanisms that govern gene regulation, it is imperative to study their combined mode of action and interconnectivity. However, it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ceea3792b260d90cd336cf2c83a74f
https://doi.org/10.1101/2023.01.18.524584
https://doi.org/10.1101/2023.01.18.524584
Autor:
Stefan Both, Johannes A. Langendijk, A. Bannink-Gawryszuk, M. Landeweerd, Roelien H. Enting, D. Scandurra, H van der Weide, Ingeborg Bosma, Miranda C. A. Kramer, Mart A. A. M. Heesters
Publikováno v:
Radiotherapy and Oncology. 161:S103-S105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::779e8e15d6f376bfe327bf9766e521c4
https://doi.org/10.1016/s0167-8140(21)07261-3
https://doi.org/10.1016/s0167-8140(21)07261-3
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160036 (2016)
Unmapped next-generation sequencing reads are typically ignored while they contain biologically relevant information. We systematically analyzed unmapped reads from whole genome sequencing of 33 inbred rat strains. High quality reads were selected an
Externí odkaz:
https://doaj.org/article/9e791ea1573e40bb84c7614fe286481b
Autor:
Emilia Dimitrova, Angelika Feldmann, Robin H. van der Weide, Koen D. Flach, Anna Lastuvkova, Elzo de Wit, Robert J. Klose
Publikováno v:
Nature structuralmolecular biology. 29(10)
Precise control of gene expression underpins normal development. This relies on mechanisms that enable communication between gene promoters and other regulatory elements. In embryonic stem cells (ESCs), the cyclin-dependent kinase module Mediator com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6056f141fbb5a270a043792e5d76d3
https://pubmed.ncbi.nlm.nih.gov/36220895
https://pubmed.ncbi.nlm.nih.gov/36220895
Akademický článek
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Autor:
Mikhail Magnitov, Tom van Schaik, Ning Qing Liu, Elzo de Wit, Robin H. van der Weide, Hans Teunissen, Marijne M.G.A. Schijns, Bas van Steensel
Publikováno v:
bioRxiv
SUMMARYThe interphase genome is mainly shaped by cohesin-mediated loop extrusion and cohesin-independent compartmentalization. Extrusion is a dynamic process of cohesin loading, loop extension and release. Cohesin release is mediated by WAPL. Loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e54450e542673c10c4172084861cd61
https://doi.org/10.1101/2021.08.27.457977
https://doi.org/10.1101/2021.08.27.457977
Autor:
Robin H. van der Weide, Ji-Ying Song, David J. Adams, Elzo de Wit, Rajith Bhaskaran, Hans Teunissen, Margriet Snoek, Jan-Paul Lambooij, Paul Krimpenfort, Anton Berns
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications
Cdkn2ab knockout mice, generated from 129P2 ES cells develop skin carcinomas. Here we show that the incidence of these carcinomas drops gradually in the course of backcrossing to the FVB/N background. Microsatellite analyses indicate that this cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9713ac1c61e57be913f7349fad7c17
https://doaj.org/article/88bea2f7c3a344d1b33663cb6275c20c
https://doaj.org/article/88bea2f7c3a344d1b33663cb6275c20c
Autor:
Elzo de Wit, Judith H.I. Haarhuis, Robin H. van der Weide, Hans Teunissen, Teun van den Brand, Benjamin D. Rowland
Publikováno v:
NAR Genomics and Bioinformatics
Conformation capture-approaches like Hi-C can elucidate chromosome structure at a genome-wide scale. Hi-C datasets are large and require specialised software. Here, we present GENOVA: a user-friendly software package to analyse and visualise chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1e9d51e89aa0d66f3de837ac22f92e