Zobrazeno 1 - 10
of 4 692
pro vyhledávání: '"H, Zetterberg"'
Autor:
B.N. Lizama, H.A. North, K. Pandey, C. Williams, D. Duong, E. Cho, V. Di Caro, L. Ping, K. Blennow, H. Zetterberg, J. Lah, A.I. Levey, M. Grundman, A.O. Caggiano, N.T. Seyfried, M.E. Hamby
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106575- (2024)
CT1812 is a novel, brain penetrant small molecule modulator of the sigma-2 receptor (S2R) that is currently in clinical development for the treatment of Alzheimer's disease (AD). Preclinical and early clinical data show that, through S2R, CT1812 sele
Externí odkaz:
https://doaj.org/article/6d00f43c2b9e41fda59027091db73805
Autor:
A. Jeppsson, Å. Sandelius, A. Zettergren, S. Kern, I. Skoog, K. Blennow, H. Zetterberg, C. Wikkelsø, P. Hellström, M. Tullberg
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-8 (2023)
Abstract Background Neurofilament light chain protein (NFL), a marker of neuronal axonal degeneration, is increased in cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). Assays for analysis of NFL in plasma ar
Externí odkaz:
https://doaj.org/article/b04f5fdf546d4ad4ab16755ac118f9de
Autor:
Gabriele Cattaneo, Javier Solana-Sánchez, Kilian Abellaneda-Pérez, Cristina Portellano-Ortiz, Selma Delgado-Gallén, Vanessa Alviarez Schulze, Catherine Pachón-García, H. Zetterberg, Jose Maria Tormos, Alvaro Pascual-Leone, David Bartrés-Faz
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
In recent years, supported by new scientific evidence, the conceptualization of cognitive reserve (CR) has been progressively enriched and now encompasses not only cognitive stimulating activities or educational level, but also lifestyle activities,
Externí odkaz:
https://doaj.org/article/22cb2f61f546448a84e985f398739755
Autor:
K. Minta, G. Brinkmalm, S. Janelidze, S. Sjödin, E. Portelius, E. Stomrud, H. Zetterberg, K. Blennow, O. Hansson, U. Andreasson
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background The human APOE gene, which codes for apolipoprotein E (apoE), has three major polymorphic alleles: ε2, ε3, and ε4 that give rise to amino acid substitutions. APOE-ε4 is a strong risk factor of sporadic Alzheimer’s disease (A
Externí odkaz:
https://doaj.org/article/1cc063aa72d2400893123db4cd563d4b
Autor:
J.P. Posti, V.F. Newcombe, N.J. Ashton, B. Glocker, A. Mankletow, D.A. Chatfield, S. Winzeck, E. Needham, M.M. Correia, G.B. Williams, J. Simrén, R.S. Takala, A.J. Katila, H.-R. Maanpää, J. Tallus, J. Frantzén, K. Blennow, O. Tenovuo, H. Zetterberg, D.K. Menon
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 101310- (2022)
Externí odkaz:
https://doaj.org/article/2f5ec0c28b7a4e199a66d3d49e9068c8
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 5, Iss , Pp 100044- (2021)
Background: Neurofilament Light (NFL) is a promising biomarker of neuroaxonal injury. Its utility may be improved by expression relative to age-matched controls and by adjusting for other covariates, such as body mass index. It has recently been sugg
Externí odkaz:
https://doaj.org/article/4812b5844efc4702b302f01bef986b12
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-6 (2019)
Abstract Background We aimed to assess the relationship between levels of a cerebrospinal fluid (CSF) marker of pericyte damage, soluble platelet-derived growth factor receptor β (sPDGFRβ) and CSF markers of blood-brain barrier (BBB) integrity (CSF
Externí odkaz:
https://doaj.org/article/cf7184b084034452a39d048f2f9113db
Autor:
I. Hossain, M. Mohammadian, H.-R. Maanpää, R. Takala, O. Tenovuo, J. Frantzén, P. Hutchinson, D. Menon, V. Newcombe, K. Blennow, J.-C. Sanchez, H. Zetterberg, J. Posti
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100615- (2021)
Externí odkaz:
https://doaj.org/article/8032db722cec4d33a6e8b8f98f208678
Autor:
V. Velickaite, V. Giedraitis, K. Ström, I. Alafuzoff, H. Zetterberg, L. Lannfelt, L. Kilander, E-M. Larsson, M. Ingelsson
Publikováno v:
BMC Geriatrics, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background The Alzheimer’s disease (AD) brain displays atrophy with amyloid-β (Aβ) and tau deposition, whereas decreased Aβ42 and increased tau are measured in cerebrospinal fluid (CSF). The aim of this study was to relate cognitive per
Externí odkaz:
https://doaj.org/article/2199c0eb798c468094b4ea7df60d89b4
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