Zobrazeno 1 - 10
of 9 017
pro vyhledávání: '"H, Young"'
Autor:
Olena Said, Dominic Stringer, Ece Sengun Filiz, Hiba Mutwalli, Sevgi Bektas, Melahat Nur Akkese, Vanessa Kellermann, Katie Ireland, Elizabeth Tyrrell-Bunge, Demelza Beishon-Murley, Joel W. T. Khor, Lee Allman, Joanna Barker, Nicus Kotze, Ben Carter, Mima Simic, Dilveer Singh Sually, Jessica Bentley, Allan H. Young, Sloane Madden, Sarah Byford, Sabine Landau, Vanessa Lawrence, Janet Treasure, Ulrike Schmidt, Dasha Nicholls, Hubertus Himmerich
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Despite the availability of evidence-based treatments for anorexia nervosa (AN), remission rates are moderate, and mortality is high. Olanzapine is used as adjunct therapy for AN in case of insufficient response to first-line trea
Externí odkaz:
https://doaj.org/article/a14830d04aa54346b5089f6fe0fd8181
Autor:
Praveen Neeli, Perry Ayn Mayson A. Maza, Dafei Chai, Dan Zhao, Xen Ping Hoi, Keith Syson Chan, Ken H. Young, Yong Li
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Multiple myeloma (MM), a hematological malignancy of the bone marrow, remains largely incurable. The orphan G protein-coupled receptor, GPRC5D, which is uniquely expressed in plasma cells and highly expressed in MM, is a compelling candidate
Externí odkaz:
https://doaj.org/article/2a29d458e1ab4ff8b1f12beabb5f483d
Autor:
Thomas J. Yamashita, Humberto L. Perotto-Baldivieso, David B. Wester, Kevin W. Ryer, Richard J. Kline, Michael E. Tewes, John H. Young, Jason V. Lombardi
Publikováno v:
Ecological Processes, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract Background Complexity in landscape structure is often assessed using individual metrics related to ecological processes. However, this rarely incorporates important relationships among metrics and may miss landscape structure effects. Multiv
Externí odkaz:
https://doaj.org/article/83c13d71258349ce8526cd5461475172
Autor:
Ali-Reza Ghazi-Noori, Rachel D. Woodham, Hakimeh Rezaei, Mhd Saeed Sharif, Elvira Bramon, Philipp Ritter, Michael Bauer, Allan H. Young, Cynthia H.Y. Fu
Publikováno v:
International Journal of Bipolar Disorders, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Current treatments for bipolar depression have limited effectiveness, tolerability and acceptability. Transcranial direct current stimulation (tDCS) is a novel non-invasive brain stimulation method that has demonstrated treatment
Externí odkaz:
https://doaj.org/article/83204f17bdea42429c8764769a72977a
Autor:
Michael W. Rudokas, Margaret McKay, Zeren Toksoy, Julia N. Eisen, Markus Bögner, Lawrence H. Young, Fadi G. Akar
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Mitochondria play a central role in cellular energy metabolism, and their dysfunction is increasingly recognized as a critical factor in the pathogenesis of diabetes-related cardiac pathophysiology, including vulnerability to ischemic events
Externí odkaz:
https://doaj.org/article/b2f397b4ab4b47cc82c3cdc543d7e8d2
Autor:
Zijun Y. Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T. Wang, Alyssa F. Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Anamarija M. Perry, Wenting Song, Dennis O’Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B. Møller, Benjamin M. Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J.M. Ferreri, Aliyah R. Sohani, Jeremy S. Abramson, Bing Xu, Ken H. Young
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Deficient (d) DNA mismatch repair (MMR) is a biomarker predictive of better response to PD-1 blockade immunotherapy in solid tumors. dMMR can be caused by mutations in MMR genes or by protein inactivation, which can be detected by sequencing and immu
Externí odkaz:
https://doaj.org/article/5de2138da31648e09e4ad55f932a3cf2
Autor:
Andrea Ulrichsen, Elliot Hampsey, Rosie H. Taylor, Romayne Gadelrab, Rebecca Strawbridge, Allan H. Young
Publikováno v:
BJPsych Open, Vol 10 (2024)
Externí odkaz:
https://doaj.org/article/ed546e3bd1a44e47bfb9334245502089
Publikováno v:
BJPsych Open, Vol 10 (2024)
Background Existing self-rated depression measurement tools possess a range of psychometric drawbacks, spanning a range of validity and reliability constructs. The gold standard self-rated depression scales contain several variable items that are oft
Externí odkaz:
https://doaj.org/article/216bd3c8a1c24913aac7bc65e3f93f24
Autor:
Kelly M Wawrzyniak, Giles Hooker, Susana Cristina Osorno Upegui, Rommer Alex Ortega Martínez, Adriana Bazoberry, David J DiBenedetto, Brent H Young, Carlos F Bazoberry
Publikováno v:
Journal of Global Health Reports, Vol 8 (2024)
# Background Oxygen is critical to the prevention of hypoxemia-induced morbidity and mortality; yet, access remains inadequate in most low- and middle-income countries despite billions of dollars spent over decades to increase supply. We present a n
Externí odkaz:
https://doaj.org/article/2f2741e8a87543a2b9a6874aea528dd5
Autor:
Dafei Chai, Junhao Wang, Chunmei Fan, Jing-Ming Lim, Xu Wang, Praveen Neeli, Xinfang Yu, Ken H. Young, Yong Li
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-23 (2024)
Abstract Background p53, the most frequently mutated gene in cancer, lacks effective targeted drugs. Methods We developed monoclonal antibodies (mAbs) that target a p53 hotspot mutation E285K without cross-reactivity with wild-type p53. They were del
Externí odkaz:
https://doaj.org/article/c893d2f686c94ed580b6f8dd6e662166