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Akademický článek

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Differential effects of prednisolone and indomethacin on zymosaninduced inflammation in a modified murine tissue-chamber model

Autor: Janet Dawson, A. O. Oluyomi, H Towbin, Hiep Nguyen, Klaus Vosbeck

Publikováno v: Inflammation Research. 44:350-356

A tissue-chamber model of inflammation in mice has been modified and used to investigate the kinetics of zymosan-induced inflammatory mediators such as tumour necrosis factor alpha (TNF alpha), interleukin-1 beta (IL-1 beta) and prostaglandin E2 (PGE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df18b3c79373aa94006fb95b1e73def
https://doi.org/10.1007/bf01796267

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Production of interleukin-1 receptor antagonist, inflammatory chemotactic proteins, and prostaglandin E by rheumatoid and osteoarthritic synoviocytes--regulation by IFN-gamma and IL-4

Autor: M Seitz, P Loetscher, B Dewald, H Towbin, M Ceska, M Baggiolini

Publikováno v: The Journal of Immunology. 152:2060-2065

This study analyzes the effects of the T cell cytokines IL-4 and IFN-gamma on the spontaneous and stimulated production of IL-8, MCP-1, IL-1 receptor antagonist (IL-1ra), and PGE by synoviocytes from rheumatoid arthritis (RA) and osteoarthritis (OA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::864050be2b710caaac247af357637f3a
https://doi.org/10.4049/jimmunol.152.4.2060

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In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs

Autor: M, Seitz, P, Loetscher, B, Dewald, H, Towbin, M, Baggiolini

Publikováno v: The Journal of rheumatology. 24(8)

To assess the effect of various antirheumatic drugs on cytokine, cytokine inhibitor, and prostaglandin E (PGE) production by normal blood mononuclear cells (MNC) and rheumatoid arthritis (RA) synovial fibroblasts in vitro.MNC from healthy donors and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b55615a1ae771db1660851e08c61bea6
https://pubmed.ncbi.nlm.nih.gov/9263137

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Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors, IL-1 beta, and IL-8--markers of remission in rheumatoid arthritis during treatment with methotrexate

Autor: M, Seitz, P, Loetscher, B, Dewald, H, Towbin, C, Rordorf, H, Gallati, N J, Gerber

Publikováno v: The Journal of rheumatology. 23(9)

To examine circulating levels of cytokines and cytokine inhibitors and their production by blood mononuclear cells (MNC) in patients with active rheumatoid arthritis (RA) before treatment with methotrexate (MTX) and inactive disease upon treatment as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::89d4d8123ed0e4815de3e21f397950d4
https://pubmed.ncbi.nlm.nih.gov/8877917

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METHOTREXATE ACTION IN RHEUMATOID ARTHRITIS: STIMULATION OF CYTOKINE INHIBITOR AND INHIBITION OF CHEMOKINE PRODUCTION BY PERIPHERAL BLOOD MONONUCLEAR CELLS

Autor: M. Baggiolini, H Towbin, N. J. Gerber, B. Dewald, C. Rordorf, Michael Seitz, Harald Gallati, Pius Loetscher

Publikováno v: Seitz, M.; Loetscher, P.; Dewald, B.; Towbin, H.; Rordorf, C.; Gallati, H.; Baggiolini, M.; Gerber, N. J. (1995). METHOTREXATE ACTION IN RHEUMATOID ARTHRITIS: STIMULATION OF CYTOKINE INHIBITOR AND INHIBITION OF CHEMOKINE PRODUCTION BY PERIPHERAL BLOOD MONONUCLEAR CELLS. Rheumatology, 34(7), pp. 602-609. Oxford University Press 10.1093/rheumatology/34.7.602

This open label study examines whether methotrexate (MTX) treatment modulates ex vivo synthesis of interleukin-1 receptor antagonist (IL-1ra), soluble tumour necrosis factor receptors (sTNFR p55 and p75), interleukin-1 beta (IL-1 beta), tumour necros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03de1235352e842d89e8b2ac1109df6
https://boris.unibe.ch/114976/1/34-7-602.pdf

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Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response

Autor: T, Geiger, H, Towbin, A, Cosenti-Vargas, O, Zingel, J, Arnold, C, Rordorf, M, Glatt, K, Vosbeck

Publikováno v: Clinical and experimental rheumatology. 11(5)

Interleukin-1 (IL-1) has been implicated in the development and progression of a variety of acute and chronic inflammatory diseases. Due to its pro-inflammatory and tissue-degrading activities, IL-1 is regarded as a major mediator of chronic inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::86abf74ec4c05051699951bc5d8e559c
https://pubmed.ncbi.nlm.nih.gov/8275587

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