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Evidence of population structuring following population genetic analyses of Fasciola hepatica from Argentina

Autor: Nicola J. Beesley, Jorge Bruno Malandrini, Cesar Ivan Pruzzo, Severo Vázquez-Prieto, José D. Álvarez, Esperanza Paniagua, Jane E. Hodgkinson, Román Vilas, Florencio M. Ubeira, H. Solana, Elizabeth Attree, Oscar Jensen

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
International Journal for Parasitology

Graphical abstract
Highlights • 320 Argentinian Fasciola hepatica were genotyped using a panel of microsatellites. • Overall there was high genotypic richness: 263 distinct genotypes were identified. • Population structuring of F. hepatica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31886b2628a3f33c2cc8b9d2f355ff3
https://hdl.handle.net/10347/26771

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Advances on metabolism and disposition of Bbnzimidazoles anthelmintic in Fasciola hepatica: its contribution to the phenomenon of anthelmintic resistance

Autor: Silvana Andrea Scarcella, H. Solana, María Victoria Solana

Publikováno v: Oxidative stress in microbial diseases
Oxidative Stress in Microbial Diseases ISBN: 9789811387623

The fascioliasis is an important zoonotic disease, particularly in underdeveloped countries. In fascioliasis, the anthelmintic control has been done mainly by the use of triclabendazole (TCBZ), which is metabolized into the anti-helmintic metabolite,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b4f221fb8b1dcf67e26e30f9e70c24
https://link.springer.com/chapter/10.1007/978-981-13-8763-0_22

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Different SNPs in Fasciola hepatica P-glycoprotein from diverse Latin American populations are not associated with Triclabendazole resistance

Autor: Silvana Andrea Scarcella, Pablo Smircich, H. Solana, José F. Tort, María Fernanda Domínguez, Santiago Radío, Silvina Fernández, María Victoria Solana

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The use of Triclabendazole for controlling fasciolosis is compromised by increased drug resistance affecting livestock and humans. Although the mode of action of TCBZ is still unknown, putative candidates and markers of resistance have been advanced.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a4a190885a96b25806b30b1acb1446
https://www.sciencedirect.com/science/article/pii/S0166685118300410

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Complex network study of the immune epitope database for parasitic organisms

Autor: Esperanza Paniagua, Severo Vázquez-Prieto, Florencio M. Ubeira, H. Solana

Background: Complex network approach allows the representation and analysis of complexsystems of interacting agents in an ordered and effective manner, thus increasing the probability of discoveringsignificant properties of them. In the present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389a367c6b8670b3cb2de12fb0e8d0af
https://www.ncbi.nlm.nih.gov/pubmed/29231143

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Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

Autor: Santiago Fontenla, Santiago Radío, H. Solana, José F. Tort, Valeria Gayo, Cristian Hoban, Guilherme Oliveira, Estefan Miranda, Victoria Solana, Anna Christina de Matos Salim, Fabiano Sviatopolk-Mirsky Pais, Pablo Smircich, Flávio Marcos Gomes Araújo, Pedro Ortiz

Publikováno v: COLIBRI
Universidad de la República
instacron:Universidad de la República
Parasites & Vectors, Vol 11, Iss 1, Pp 1-11 (2018)
Parasites & Vectors

Background Fasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting livestock worldwide, and an emerging food-borne disease in humans. Even when effective treatments are available, drugs are costly and can result in tolerance,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5960ff2d07e9213ac4214bca36929ad2

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Differential Activities of Glutathione S-Transferase Isoenzymes in Strains of Fasciola Hepatica Susceptible and Resistant to Triclabendazole

Autor: H. Solana, V. Fernández, M.V. Solana, Pedro Ortiz

Publikováno v: American Journal of Animal and Veterinary Sciences. 9:177-181

Fil: Fernandez, Vanesa. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Tandil. Centro de Investigacion Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49702d3e09c397094d34906857cb70fa
https://doi.org/10.3844/ajavsp.2014.177.181

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A study of the Immune Epitope Database for some fungi species using network topological indices

Autor: Esperanza Paniagua, Humberto González-Díaz, Severo Vázquez-Prieto, Florencio M. Ubeira, H. Solana

Publikováno v: Molecular diversity. 21(3)

In the last years, the encryption of system structure information with different network topological indices has been a very active field of research. In the present study, we assembled for the first time a complex network using data obtained from th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd86b07b0897e15db6f4d144c045dd31
https://pubmed.ncbi.nlm.nih.gov/28567560

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Fasciola hepatica: Histological changes in the somatic and reproductive tissues of liver fluke following closantel treatment of experimentally-infected sheep

Autor: S. Scarcella, H. Solana, G.P. Brennan, Ian Fairweather, R.E.B. Hanna

Lambs infected with the Cullompton isolate of Fasciola hepatica were treated orally or subcutaneously with 10 mg/kg of closantel at 16 weeks post-infection. Adult flukes were recovered from the liver of individual animals at 12 h, 24 h, or 36 h post-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1826ad8bd96b164b3e34b70843549a1a
http://www.sciencedirect.com/science/article/pii/S0304401715300662

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In vivo assessment of closantel ovicidal activity in Fasciola hepatica eggs

Autor: Gisela Neira, Roberto Mera y Sierra, Silvana Andrea Scarcella, María Victoria Solana, H. Solana

Publikováno v: UMaza Digital
Universidad Maza
instacron:UMAZA

Anthelmintic resistance in livestock parasites is currently a worldwide problem.Fasciola hepatica is a cosmopolitan parasite which causes considerable loss in sheep and cattle production systems all over the world. Chemotherapy is currently the main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9bb39b7e90612f3928b72da9678d8f
http://www.sciencedirect.com/science/article/pii/S0014489415300576

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Early onset of changes to the reproductive system of Fasciola hepatica following in vivo treatment with triclabendazole

Autor: S. McConnell, R.E.B. Hanna, H. Solana, S. Scarcella, Ian Fairweather

Publikováno v: Veterinary Parasitology. 184:341-347

Lambs infected with the Cullompton triclabendazole (TCBZ)-susceptible isolate of Fasciola hepatica were treated with TCBZ at a dosage of 10 mg/kg at 16 weeks post-infection. Adult flukes were recovered from the liver at 3 h, 24 h, 48 h and 60 h post-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5420bdb23838f87604e4957029fafb9c
https://doi.org/10.1016/j.vetpar.2011.08.023

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