Zobrazeno 1 - 10
of 13
pro vyhledávání: '"H, Schafer P"'
Autor:
Oday Salman, Lei Zhao, Jordana B. Cohen, Marie Joe Dib, Joe David Azzo, Sushrima Gan, A. Mark Richards, Bianca Pourmussa, Rob Doughty, Ali Javaheri, Douglas L. Mann, Ernst Rietzschel, Manyun Zhao, Zhaoqing Wang, Christina Ebert, Vanessa van Empel, Karl Kammerhoff, Joseph Maranville, Joseph Gogain, Jaclyn Dennis, Peter H. Schafer, Dietmar Seiffert, David A. Gordon, Francisco Ramirez‐Valle, Thomas P. Cappola, Julio A. Chirinos
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background Kidney disease is common in heart failure with preserved ejection fraction (HFpEF). However, the biologic correlates and prognostic significance of kidney injury (KI), in HFpEF, beyond the estimated glomerular filtration rate (eGFR), are u
Externí odkaz:
https://doaj.org/article/005acfdc8a4844deafa49b506123ac19
Autor:
Oday Salman, Payman Zamani, Lei Zhao, Marie Joe Dib, Sushrima Gan, Joe David Azzo, Bianca Pourmussa, Arthur Mark Richards, Ali Javaheri, Douglas L. Mann, Ernst Rietzschel, Manyun Zhao, Zhaoqing Wang, Christina Ebert, Laura Liu, Kushan L. Gunawardhana, Danielle Greenawalt, Leon Carayannopoulos, Ching‐Pin Chang, Vanessa van Empel, Joseph Gogain, Peter H. Schafer, David A. Gordon, Francisco Ramirez‐Valle, Thomas P. Cappola, Julio A. Chirinos
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background The role of cellular senescence in human heart failure (HF) remains unclear. The senescence‐associated secretory phenotype (SASP) is composed of proteins released by senescent cells. We assessed the prognostic significance and biologic p
Externí odkaz:
https://doaj.org/article/9ce69a1294c446d9a935a66c5df06d36
Autor:
Corinne Carland, Lei Zhao, Oday Salman, Jordana B. Cohen, Payman Zamani, Qing Xiao, Ashok Dongre, Zhaoqing Wang, Christina Ebert, Danielle Greenawalt, Vanessa van Empel, A. Mark Richards, Robert N. Doughty, Ernst Rietzschel, Ali Javaheri, Yixin Wang, Peter H. Schafer, Sarah Hersey, Leonidas N. Carayannopoulos, Dietmar Seiffert, Ching‐Pin Chang, David A. Gordon, Francisco Ramirez‐Valle, Douglas L. Mann, Thomas P. Cappola, Julio A. Chirinos
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Although several studies have addressed plasma proteomics in heart failure with preserved ejection fraction, limited data are available on the prognostic value of urinary proteomics. The objective of our study was to identify urinary prote
Externí odkaz:
https://doaj.org/article/31d03371ea994940952d131d3a850e78
Autor:
Domenico Mercurio, Stefano Fumagalli, Martin K-H Schafer, Jordi Pedragosa, Lionel Dejeumen Claude Ngassam, Verena Wilhelmi, Sarah Winterberg, Anna M. Planas, Eberhard Weihe, Maria-Grazia De Simoni
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The activation of microglia and the infiltration of macrophages are hallmarks of neuroinflammation after acute brain injuries, including traumatic brain injury (TBI). The two myeloid populations share many features in the post-injury inflammatory res
Externí odkaz:
https://doaj.org/article/670028469d06453f9647bdbad65fe2ec
Autor:
Victoria P Werth, Richard A Furie, Ying Ye, Xiaojiang Zhan, Peter H Schafer, Nikolay Delev, Shimon Korish, Michael Weiswasser, Douglas R Hough, Allison Gaudy
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/42114d85d2d14912be0992652a48bf4b
Autor:
Peter H. Schafer, Alan J. Kivitz, Jianglin Ma, Shimon Korish, Donna Sutherland, Li Li, Ada Azaryan, Jolanta Kosek, Mary Adams, Lori Capone, Eun Mi Hur, Douglas R. Hough, Garth E. Ringheim
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 1, Pp 101-119 (2019)
Abstract Introduction Spebrutinib (CC-292) is an orally administered, covalent, small-molecule inhibitor of Bruton’s tyrosine kinase (BTK), part of the B-cell and Fc receptor signaling pathways. This study evaluated spebrutinib pharmacology and mec
Externí odkaz:
https://doaj.org/article/39d20490cb6e49508dbe1a45ca6893e9
Autor:
Peter H. Schafer, Mary Adams, Gerald Horan, Francesca Truzzi, Alessandra Marconi, Carlo Pincelli
Publikováno v:
Drugs in R&D, Vol 19, Iss 4, Pp 329-338 (2019)
Abstract Background Apremilast, an oral phosphodiesterase (PDE) 4 inhibitor, has demonstrated efficacy in psoriasis, while its efficacy in atopic dermatitis (AD) was found to be modest. AD is a chronic inflammatory skin disease associated with activa
Externí odkaz:
https://doaj.org/article/6311f234a8234e55843aa86a3e9e665f
Autor:
Soyoung Kwon, Markus H. Schafer
Publikováno v:
SSM: Population Health, Vol 2, Iss , Pp 77-83 (2016)
This study examines temporal trends in the self-rated health of Chinese adults from 1990 to 2012. Concentration on this particular period in Chinese history provides insights into the health implications of China’s massive societal transformation i
Externí odkaz:
https://doaj.org/article/267c1242581340e993684a02d5c148b3
Autor:
Weiqian Chen, Julie Wang, Zhenjian Xu, Feng Huang, Wenbin Qian, Jilin Ma, Hwa bok Wee, Gregory S. Lewis, Rayford R. June, Peter H. Schafer, Jin Lin, Song Guo Zheng
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Apremilast is a novel phosphodiesterase 4 (PDE4) inhibitor suppressing immune and inflammatory responses. We assessed the anti-inflammatory effects of Apremilast in type II collagen (CII)-induced arthritis (CIA) mouse model. To determine whether Apre
Externí odkaz:
https://doaj.org/article/40cf4d87d17247b2ae2579960406c16d
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Apremilast, an oral phosphodiesterase 4 inhibitor, demonstrated effectiveness (versus placebo) for treatment of active psoriatic arthritis in the psoriatic arthritis long-term assessment of clinical efficacy (PALACE) phase III clinical trial program.
Externí odkaz:
https://doaj.org/article/48a9a073ea914ccc9b94d9086f6650b5