Zobrazeno 1 - 10
of 60
pro vyhledávání: '"H, Sasmor"'
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 19:533-543
Extensive investigations on the influence of diastereomeric ratios of deoxyribonucleoside phosphoramidites on stereo-reproducibility of solid phase synthesis of phosphorothioate oligodeoxyribonucleotides via the phosphoramidite approach indicate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f474c80aec17a51ffc57a20473eea5e9
https://doi.org/10.1080/15257770008035005
https://doi.org/10.1080/15257770008035005
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0b815eb7216453023dffbc6ffff609
https://doi.org/10.1002/chin.199427070
https://doi.org/10.1002/chin.199427070
Autor:
R S, Geary, O, Khatsenko, K, Bunker, R, Crooke, M, Moore, T, Burckin, L, Truong, H, Sasmor, A A, Levin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(3)
Three modified 20-mer antisense oligonucleotides targeted to human intercellular adhesion molecule-1 mRNA were characterized for their presystemic stability and oral bioavailability compared with a first-generation phosphorothioate oligodeoxynucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9344003f312f6404237956bf9547a755
https://pubmed.ncbi.nlm.nih.gov/11181922
https://pubmed.ncbi.nlm.nih.gov/11181922
Autor:
R S, Geary, T A, Watanabe, L, Truong, S, Freier, E A, Lesnik, N B, Sioufi, H, Sasmor, M, Manoharan, A A, Levin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(3)
Plasma pharmacokinetics, biodistribution, excretion, and metabolism of four modified 20-mer antisense oligonucleotides targeted to human intercellular adhesion molecule-1 mRNA have been characterized in rats and compared with a first-generation phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6aad7853c4bf95059fa77969d1ce76d0
https://pubmed.ncbi.nlm.nih.gov/11181921
https://pubmed.ncbi.nlm.nih.gov/11181921
Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes
Autor:
Ronnie C. Hanecak, M C Fox, S Furusako, R F Azad, Vickie L. Brown-Driver, Kevin P. Anderson, Chikateru Nozaki, H Sasmor, C Ford
Genetic and biochemical studies have provided convincing evidence that the 5' noncoding region (5' NCR) of hepatitis C virus (HCV) is highly conserved among viral isolates worldwide and that translation of HCV is directed by an internal ribosome entr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa0e5533db5d9fc3d86b8cf8cbe1537
https://europepmc.org/articles/PMC190476/
https://europepmc.org/articles/PMC190476/
Autor:
P A, Cossum, H, Sasmor, D, Dellinger, L, Truong, L, Cummins, S R, Owens, P M, Markham, J P, Shea, S, Crooke
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
5'-TTGCTTCCATCTTCCTCGTC-3' (ISIS 2105) is a phosphorothioate oligodeoxynucleotide currently being evaluated as an intralesional antiviral drug for the treatment of genital warts that are caused by the human papillomavirus. ISIS 2105, labeled with 14C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcdc6e6a6fe390e76977e3c3ae779e71
https://pubmed.ncbi.nlm.nih.gov/8166890
https://pubmed.ncbi.nlm.nih.gov/8166890
Autor:
M H, Caruthers, G, Beaton, L, Cummins, D, Graff, Y X, Ma, W S, Marshall, H, Sasmor, P, Norris, E K, Yau
Publikováno v:
Ciba Foundation symposium. 158
Dithioate DNA was synthesized and used for various biochemical studies. Results from these studies indicate that dithioate DNA is a potent inhibitor of HIV Reverse Transcriptase, activates endogenous RNase H in HeLa cell nuclear extracts, and is a us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08726a60f4661133fdd0ffd6b2318364
https://pubmed.ncbi.nlm.nih.gov/1718668
https://pubmed.ncbi.nlm.nih.gov/1718668
Autor:
M H, Caruthers, G, Beaton, L, Cummins, D, Graff, M, Hall, W S, Marshall, H, Sasmor, W, Wiesler
Publikováno v:
Nucleic acids symposium series. (24)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f58f403efc495a41b579fec173b9b25
https://pubmed.ncbi.nlm.nih.gov/1726757
https://pubmed.ncbi.nlm.nih.gov/1726757
Autor:
S, Geary R, O, Khatsenko, K, Bunker, R, Crooke, M, Moore, T, Burckin, L, Truong, H, Sasmor, A, Levin A
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; March 2001, Vol. 296 Issue: 3 p898-904, 7p
Autor:
S, Geary R, A, Watanabe T, L, Truong, S, Freier, A, Lesnik E, B, Sioufi N, H, Sasmor, M, Manoharan, A, Levin A
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; March 2001, Vol. 296 Issue: 3 p890-7, 8p