Zobrazeno 1 - 10
of 473
pro vyhledávání: '"H, Saied"'
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Background HER2-positive breast cancer occurs in 15–20% of breast cancer patients and is characterized by poor prognosis. Trastuzumab is considered the key drug for treatment of HER2-positive breast cancer patients. It improves patient sur
Externí odkaz:
https://doaj.org/article/78b91233be6f48c0bc9b1205e671c285
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Ovarian cancer (OC) is considered a leading cause of death among women with gynecological malignancies. OC, like breast cancer, shows a familial predisposition to germline mutations in genes BRCA1 or BRCA2, which have proved to pl
Externí odkaz:
https://doaj.org/article/247922d45a754f96991fdba0b6ea46b5
Publikováno v:
Tikrit Journal for Agricultural Sciences, Vol 21, Iss 1 (2021)
A comparative agronomical experiment was conducted at research station/ Department of Horticulture and Landscape/ College of Agriculture/ Tikrit University, to study the effect of two different soil textures (loam and silt loam) on growth and yield o
Externí odkaz:
https://doaj.org/article/e84c99de6537498b9540142bfb08a5dd
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 19, Iss 2, Pp 87-90 (2018)
Background: DNA methylation is the commonest known epigenetic change that results in silencing of tumor suppressor genes. Promoter methylation of tumor suppressor genes has the potential for early detection of breast cancer. Aim: Aim is to examine th
Externí odkaz:
https://doaj.org/article/44adcbc4089e439c9c5e2e9b97beba89
Publikováno v:
Luminescence. 37:134-140
In this paper, two simple, rapid and highly sensitive spectrofluorimetric methods were developed and validated for nystatin determination in its pure form and pharmaceutical dosage form (oral suspension). The first method was based on measuring the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eee9439bb7442aeb12b16c61a831187
https://doi.org/10.1002/bio.4154
https://doi.org/10.1002/bio.4154
Publikováno v:
Annals of Biomedical Engineering. 49:2006-2029
The most common forms of tissue impairment are fracture bones and significant bone disorders caused by multiple traumas or normal aging. Surgical care sometimes necessitates the placement of a temporary or permanent prosthesis, which continues to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67d256aad5d58b271cec957c52a7d575
https://doi.org/10.1007/s10439-021-02810-2
https://doi.org/10.1007/s10439-021-02810-2
Autor:
Detlef Bockenhauer, François Dragon, Christelle Arrondel, Ákos Szekeres, Kristóf Perczel, Wei-Li Di, Susanne Motameny, Attila Fintha, Maria Kolatsi-Joannou, Eszter Jávorszky, Guillaume Dorval, Salah Marzouk, Kazunori Tomita, Jennifer C. Chandler, Peter Nürnberg, Gusztáv Schay, Veronica A. Kinsler, Ahmed Hossain, Andrea Kerti, András Perczel, Hafsa Hammid, Magdolna Kardos, William Mifsud, Florentina Sava, David Curtis, Corinne Antignac, Felipe D’Arco, Aoife M. Waters, Géraldine Mollet, Mona Tahoun, Gergely Toldi, Tivadar Tulassay, Ana Faro, Anna Szőcs, Jutta Koeglmeier, Kata Kelen, Marwa H. Saied, Holger Thiele, Hywel Williams, Kálmán Tory, Renáta Hamar, Erika Maka, Mario Kaliakatsos, Mariya Moosajee, Gábor Rudas, Máté Varga, Eszter Balogh, Attila Szabo, Dóra K. Menyhárd, Horia Stanescu, Tomas Goncalves, Olivier Gribouval, Regina Légrádi, George S. Reusz, Robert Kleta, Judit Götze, David A. Long
Publikováno v:
Proceedings of the National Academy of Sciences. 117:15137-15147
RNA modifications play a fundamental role in cellular function. Pseudouridylation, the most abundant RNA modification, is catalyzed by the H/ACA small ribonucleoprotein (snoRNP) complex that shares four core proteins, dyskerin (DKC1), NOP10, NHP2, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c70950ec857554bf1e04d93236b91c
https://doi.org/10.1073/pnas.2002328117
https://doi.org/10.1073/pnas.2002328117
Autor:
Randal Stronge, Paul Smith, Simon P. Joel, Marwa H. Saied, Lola Koniali, Adedayo Oke, David Taussig, Bryan D. Young, Farideh Miraki-Moud, Essam Ghazaly, Janet Matthews, John G. Gribben, Robert D. Petty, Chathunissa Gnanaranjan
Publikováno v:
The Journal of Biological Chemistry
Previous studies have shown that sphingosine kinase interacting protein (SKIP) inhibits sphingosine kinase (SK) function in fibroblasts. SK phosphorylates sphingosine producing the potent signaling molecule sphingosine-1-phosphate (S1P). SKIP gene (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f9a1747fce13819719b027b13c282b
https://doi.org/10.1074/jbc.ra119.010467
https://doi.org/10.1074/jbc.ra119.010467
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Up to half of the heritable mutations in breast cancer (BC) are attributed to BRCA1 and BRCA2 genes. The mutation prevalence is variable based on ethnicity and may be influenced by founder mutations. The aim of this pilot study is to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36acc994ebec3cf3e388360450e025b2
https://doi.org/10.31557/apjcp.2020.21.2.431
https://doi.org/10.31557/apjcp.2020.21.2.431
Autor:
Mona Tahoun, Reham Fadl, Inas Ibrahim, Dalal El-Kaffash, Alyaa Elkayal, Marwa H. Saied, Reham Abdel Haleem, Amal Refeat, Eman Tayae
Publikováno v:
Molecular Medicine Reports. 24
Breast cancer (BC) is the most commonly diagnosed cancer worldwide and a major health concern in Egypt. There is a known association between pathogenic variants identified in breast cancer susceptibility gene (BRCA)1 and 2 and the risk of developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7684688cf64c0a8975c7b3ce67a64f64
https://doi.org/10.3892/mmr.2021.12317
https://doi.org/10.3892/mmr.2021.12317