Zobrazeno 1 - 10
of 401
pro vyhledávání: '"H, SPECTOR"'
Autor:
Emilie Branche, Ying-Ting Wang, Karla M. Viramontes, Joan M. Valls Cuevas, Jialei Xie, Fernanda Ana-Sosa-Batiz, Norazizah Shafee, Sascha H. Duttke, Rachel E. McMillan, Alex E. Clark, Michael N. Nguyen, Aaron F. Garretson, Jan J. Crames, Nathan J. Spann, Zhe Zhu, Jeremy N. Rich, Deborah H. Spector, Christopher Benner, Sujan Shresta, Aaron F. Carlin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Zika virus (ZIKV) infection suppresses the induction of dendritic cell (DC)-derived immunity, but the underlying mechanistical insights are still lacking. Here the authors show, using in vitro systems profiling of DC transcriptome and epigenome, that
Externí odkaz:
https://doaj.org/article/8fc6f2849f18424eb3cf7370ce4d7945
Autor:
Deborah H. Spector
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974d1da46df58cf9df9fe77adccb16c4
https://doi.org/10.1096/fj.202201873
https://doi.org/10.1096/fj.202201873
Autor:
Elizabeth Nichols, María Uriarte, Carlos A Peres, Julio Louzada, Rodrigo Fagundes Braga, Gustavo Schiffler, Whaldener Endo, Sacha H Spector
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75819 (2013)
Human presence and activity in tropical forest is thought to exert top-down regulation over the various 'green-world' pathways of plant-based foodwebs. However, these effects have never been explored for the 'brown-world' pathways of fecal-detritus w
Externí odkaz:
https://doaj.org/article/df546df10b43458e86020373ecd33d4e
Publikováno v:
J Virol
Zika virus (ZIKV) is a mosquito-borne human pathogen that causes congenital Zika syndrome and neurological symptoms in some adults. There are currently no approved treatments or vaccines for ZIKV, and exploration of therapies targeting host processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff58965a1b3a7a62414d23dee287dcae
https://pubmed.ncbi.nlm.nih.gov/33328307
https://pubmed.ncbi.nlm.nih.gov/33328307
Publikováno v:
PLoS Pathogens, Vol 3, Iss 11, p e163 (2007)
Although multiple studies have documented the expression of over 70 novel virus-encoded microRNAs (miRNAs), the targets and functions of most of these regulatory RNA species are unknown. In this study a comparative bioinformatics approach was employe
Externí odkaz:
https://doaj.org/article/b74a1333d6b3415faa2180ff4cb04888
Autor:
Kimberly A. Kraynyak, Fernando J. Bravo, Christopher S. Morello, Deborah H. Spector, David I. Bernstein, Rhonda D. Cardin
Publikováno v:
Vaccine. 38(1)
Infection with Herpes Simplex Viruses (HSVs) represents a significant health burden worldwide with HSV-1 and HSV-2 causing genital disease and HSV-2 contributing to human immunodeficiency virus acquisition. Despite great need, there is currently no l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e62d1ff3b67b2275b44fb006fb7a9d
https://pubmed.ncbi.nlm.nih.gov/31611098
https://pubmed.ncbi.nlm.nih.gov/31611098
Autor:
Ronald H. Spector
Publikováno v:
Security in Korea ISBN: 9780429305702
Security in Korea
Security in Korea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::922fb60134bf3eec0ff8dc760ec642ca
https://doi.org/10.4324/9780429305702-8
https://doi.org/10.4324/9780429305702-8
Autor:
Elizabeth Clark, Jean-Philippe Belzile, Megan Craig, Deborah H. Spector, Maite Sabalza, Christopher S. Morello
Publikováno v:
Journal of Virology. 90:1259-1277
Human cytomegalovirus (HCMV) is the major viral cause of birth defects and a serious problem in immunocompromised individuals and has been associated with atherosclerosis. Previous studies have shown that the induction of autophagy can inhibit the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6e9fc3ae1b4308f3d791e52400979f
https://doi.org/10.1128/jvi.02651-15
https://doi.org/10.1128/jvi.02651-15
Publikováno v:
Journal of Virology. 92
Human cytomegalovirus (HCMV) is the top viral cause of birth defects worldwide, and current therapies have high toxicity. We previously reported that the mTOR-independent autophagy-inducing disaccharide trehalose inhibits HCMV replication in multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef015f163a22703499efee5e0d106679
https://doi.org/10.1128/jvi.02015-17
https://doi.org/10.1128/jvi.02015-17
Autor:
Deborah H. Spector, Elizabeth Clark
Publikováno v:
Journal of Virology. 89:6928-6939
Human cytomegalovirus (HCMV) deregulates the cell cycle by several means, including inactivation of the a naphase- p romoting c omplex/ c yclosome (APC/C) E3 ubiquitin ligase. Viral proteins UL97 and UL21a, respectively, affect the APC/C by phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd0334eb916d1d7574c4f7d88e1b99a
https://doi.org/10.1128/jvi.00403-15
https://doi.org/10.1128/jvi.00403-15