Zobrazeno 1 - 10
of 541
pro vyhledávání: '"H, Rorsman"'
Publikováno v:
Biochemical and Biophysical Research Communications. 197:619-624
Two membrane bound enzymes which tautomerize L-dopachrome and are specific for the L-isomer of dopachrome have been defined in melanin forming cells. Another enzyme that tautomerizes D-dopachrome with concomitant decarboxylation to give 5,6-dihydroxy
Publikováno v:
European journal of haematology. 57(3)
Publikováno v:
Acta dermato-venereologica. 75(4)
Serum samples for the analysis of tyrosinase activity were obtained from 10 healthy subjects in autumn, winter and summer. Tyrosinase was purified from 100 microl serum by adsorption to concanavalin A sepharose, the tyrosinase adsorbed to the gel bei
Publikováno v:
Melanoma research. 5(2)
We have recently described a new method for measurement of tyrosinase activity in small amounts of human serum (100 microliters), where the purification of tyrosinase is obtained by adsorption of the enzyme to concanavalin A sepharose. The method, wh
Autor:
H, Rorsman
Publikováno v:
Sydsvenska medicinhistoriska sallskapets arsskrift. 32
Publikováno v:
Lakartidningen. 89(17)
Publikováno v:
Acta dermato-venereologica. 71(5)
A sensitive competitive radioimmunoassay for quantitative analysis of tyrosinase in biological tissues has been developed. The binding sites of antityrosinase antibodies were competed for by 125I-labelled human tyrosinase and a known (standard) or un
Publikováno v:
Acta dermato-venereologica. 70(5)
5-S-Cysteinyldopac, a compound hitherto demonstrated only in brain tissue, has been isolated and quantified in urine. The urines from 12 individuals were found to contain 20 +/- 9.1 micrograms 5-S-cysteinyldopac/24 hours. Incubation of 5-S-cysteinyld
Publikováno v:
Acta dermato-venereologica. 70(4)
In the human melanoma cell tyrosinase exists in a membraneous and a soluble form. The membraneous enzyme has an N-terminal amino acid sequence identical to that predicted from a human c-DNA clone by Kwon et al.. The soluble form has now been isolated
Publikováno v:
Acta dermato-venereologica. 70(4)
The lysosomal enzyme beta-hexosaminidase and the melanocyte specific enzyme tyrosinase were examined in human melanoma cell cultures. The beta-hexosaminidase activity of the medium was approximately 40% of the total cellular activity after 24 h, whil