Výsledky vyhledávání

Reduced-toxicity conditioning with treosulfan, fludarabine and ATG as preparative regimen for allogeneic stem cell transplantation (alloSCT) in elderly patients with secondary acute myeloid leukemia (sAML) or myelodysplastic syndrome (MDS)

Autor: Djordje Atanackovic, J. Dahlke, Jens Panse, Francis Ayuk, Tatjana Zabelina, H Renges, Axel R. Zander, Arnon Nagler, N Kröger, Christine Wolschke, Avichai Shimoni, Heike Schieder

Publikováno v: Bone Marrow Transplantation. 37:339-344

We investigated a dose-reduced conditioning regimen consisting of treosulfan and fludarabine followed by allogeneic stem cell transplantation (SCT) in 26 patients with secondary AML or MDS. Twenty patients were transplanted from matched or mismatched

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d8cc4f5a033373b904f87bd94edaaf
https://doi.org/10.1038/sj.bmt.1705259

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Comparable results in patients with acute lymphoblastic leukemia after related and unrelated stem cell transplantation

Autor: A R Zander, Christine Wolschke, J. Dahlke, W Krüger, Heike Schieder, H Renges, A Kruell, Tatjana Zabelina, N. Fehse, Rudolf Erttmann, Olga Waschke, F Ayuk, Axel Hinke, N Kröger, Hartmut Kabisch

Publikováno v: Bone Marrow Transplantation. 37:155-163

We report the results of 84 patients with ALL after related (n = 46) or unrelated (n = 38) allogeneic SCT. Mean recipient age was 23 years (range: 1-60) and median follow-up was 18 months (range: 1-133). Forty-three patients were transplanted in CR1;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1971de1da6081d0ae31b5bf324b5986
https://doi.org/10.1038/sj.bmt.1705221

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Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up

Autor: H Renges, N Kröger, Tatjana Zabelina, N. Fehse, Heike Schieder, Boris Fehse, A R Zander, Hartmut Kabisch, A A Oyekunle, F Ayuk, Olga Waschke

Publikováno v: Bone Marrow Transplantation. 37:45-50

We examined retrospectively 44 patients with refractory acute leukemia (acute myeloid leukemia (AML)/acute lymphoblastic leukemia=25/19) who underwent allogeneic transplantation at our center between 11/1990 and 04/2004. The median leukemic blasts wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80e21e8e903d3cc7503d4ce0612d005
https://doi.org/10.1038/sj.bmt.1705207

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Stem cell mobilisation with 16 μg/kg vs 10 μg/kg of G-CSF for allogeneic transplantation in healthy donors

Autor: N Kröger, Kai Gutensohn, L Cortes-Dericks, Axel R. Zander, William Krüger, H Renges, S Sonnenberg, T Dielschneider

Publikováno v: Bone Marrow Transplantation. 29:727-730

We compared two doses of recombinant human granulocyte-stimulating factor (G-CSF) for stem cell mobilisation in 90 healthy donors for allogeneic stem cell transplantation in a retrospective analysis. Group I (n = 46) received 10 microg/kg G-CSF (filg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d656e1aa274a0befd3712ab06fa93b37
https://doi.org/10.1038/sj.bmt.1703509

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In vivo T cell depletion with pretransplant anti-thymocyte globulin reduces graft-versus-host disease without increasing relapse in good risk myeloid leukemia patients after stem cell transplantation from matched related donors

Autor: Rudolf Erttmann, W Krüger, Ulrika M. Schade, F. Tögel, H Renges, N Stute, J Rischewski, S Sonnenberg, H Fiegel, F Ayuk, Tatjana Zabelina, N Kröger, C Löliger, A R Zander

Publikováno v: Bone Marrow Transplantation. 29:683-689

One-hundred and two patients with good risk myeloid leukemia (CML first chronic phase or AML first CR) were transplanted from HLA-related donors after conditioning with (n = 45) or without anti-thymocyte globulin (ATG) (n = 57). One graft failure was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7688622c367fd8ffeaa01d2dc5fb518e
https://doi.org/10.1038/sj.bmt.1703530

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A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome

Autor: Johanna Schrum, N Stute, W Krüger, Wolfgang Siegert, Hartmut Kabisch, A R Zander, Tatjana Zabelina, H Renges, N Kröger, Johannes Schetelig

Publikováno v: Bone Marrow Transplantation. 28:643-647

We investigated the feasibility and efficacy of a fludarabine-based dose-reduced conditioning regimen followed by stem cell transplantation from related (n = 5) or unrelated HLA-matched donors (n = 7) in 12 patients with high risk MDS, who were not e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c4c088c02a9ec4c00f6157faf9649
https://doi.org/10.1038/sj.bmt.1703215

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Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia

Autor: U. Mayer, N Stute, Tatjana Zabelina, H Renges, A R Zander, S Sonnenberg, W Krüger, Walter Fiedler, Hartmut Kabisch, N Kröger, R. Sonnen, F. del Valle, R. Kuse, F. Finkenstein, K. Holstein, D Braumann, Bernd Metzner, H. Colberg, Rudolf Erttmann

Publikováno v: Bone Marrow Transplantation. 26:711-716

To evaluate the efficacy and toxicity of two different etoposide (VP-16) dosages (30 or 45 mg/kg) in combination with busulfan/cyclophosphamide as conditioning therapy followed by stem cell transplantation in acute myeloid leukemia (AML), 90 patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e028b68a370e7bd805a644fa61b211ae
https://doi.org/10.1038/sj.bmt.1702598

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Steady-State Mobilization of Peripheral Blood Progenitor Cells by Cytokines Alone in Patients with Solid Tumors or Hematological Malignancies

Autor: C.C. Löliger, C. Rauhöft, P. Kühnl, W. Zeller, A.R. Zander, H. Renges, W Krüger, R. Erttmann, N. Fuchs, Nicolaus Kröger, K. Gutensohn, H. T. Hassan, B Rüssmann

Publikováno v: Transfusion Medicine and Hemotherapy. 26:85-90

Cytokines are involved in hematopoiesis and cell growth regulation. Many cytokines have the property of increasing the number of hematopoietic progenitor cells circulating in peripheral blood. Since it has been shown that peripheral blood progenitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d97251d56affa4aa45ef91d9321bbe5
https://doi.org/10.1159/000053469

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Intensified conditioning regimen in bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia

Autor: Stockschläder M, H Bartels, H Renges, B Rüssmann, R. Kuse, N Kröger, W Krüger, G Wacker-Backhaus, N. Fuchs, M Dürken, Hartmut Kabisch, A R Zander, Rudolf Erttmann, S Hegewisch-Becker, Stefan S. Bielack, M de Wit, Gunter Schuch, D Braumann

Publikováno v: Bone Marrow Transplantation. 22:1029-1033

We investigated an intensified conditioning regimen including fractionated total body irradiation (12 Gy), etoposide (30–45 mg/kg) and cyclophosphamide (120 mg/kg), followed by autologous (n = 5), allo-related (n = 13) or allo-unrelated (n = 6) bon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99477aca108f9da955401228c1011d7e
https://doi.org/10.1038/sj.bmt.1701498

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