Zobrazeno 1 - 10
of 306
pro vyhledávání: '"H, Ramuz"'
Publikováno v:
Journal of Mass Spectrometry, Vol. 31, No 1 (1996) pp. 69-76
For metabolic studies the fragmentation of a novel endothelin receptor antagonist, Bosentan, was investigated using ionspray tandem mass spectrometry. Bosentan belongs to the sulphonamide class and a complicated and unexpected fragmentation at low en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc37789e06c2d75fa92c55e0d9998306
https://doi.org/10.1002/(sici)1096-9888(199601)31:1<69::aid-jms264>3.0.co
https://doi.org/10.1002/(sici)1096-9888(199601)31:1<69::aid-jms264>3.0.co
Autor:
Ikuo Horii, C. Konishi, K. Kobayashi, J.F. Eliason, R. Sawada, Shigeyasu Ichihara, Isami Kuruma, T. Tsukaguchi, H. Ramuz
Publikováno v:
European Journal of Cancer. 31:2354-2361
The multidrug resistance modifying activity of a dithiane analogue of tiapamil, Ro 44-5912, was examined in vivo . Results of acute toxicity studies in mice indicated that lethal toxicity occurred with doses greater than 1 mmol/kg of body weight. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a76072312216498f5c58abe20847ec
https://doi.org/10.1016/0959-8049(95)00418-1
https://doi.org/10.1016/0959-8049(95)00418-1
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
Tezosentan (Ro 61-0612) [5-isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1H-tetrazol-5-yl-+ ++pyri din-4-yl)-pyrimidin-4-ylamide] is a new endothelin (ET) receptor antagonist specifically designed for parenteral u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::147e1c57d12f96739f5189fb5184e644
https://pubmed.ncbi.nlm.nih.gov/10411600
https://pubmed.ncbi.nlm.nih.gov/10411600
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
Endothelin (ET) receptor antagonists are of great potential clinical interest for the treatment pathological conditions associated with vasospasm, such as subarachnoid hemorrhage (SAH). We developed for parenteral use a compound of a class of trifunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9856bcfaa9beffc3846cb2f303ececf
https://pubmed.ncbi.nlm.nih.gov/9399983
https://pubmed.ncbi.nlm.nih.gov/9399983
Publikováno v:
Helvetica Chimica Acta. 45:789-805
L'etude du systeme ternaire K+NH4+NO3H2O a 25° a conduit a un diagramme de solubilite compose de 4 courbes representant les solutions saturees des phases solides suivantes: cristaux mixtes du type KNO3 (symbole K0), contenant de 0 a 13,3 eq.-% NH4+,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79f078bbd8b158f39105ed50f83584c
https://doi.org/10.1002/hlca.19620450308
https://doi.org/10.1002/hlca.19620450308
Autor:
Jeon, Woohyung1 (AUTHOR), Baiazitov, Ramil1 (AUTHOR), Chierchia, Matteo1 (AUTHOR), Niederer, Kyle1 (AUTHOR), Ren, Hongyu1 (AUTHOR), Moon, Young‐Choon1 (AUTHOR), Gilbert, Bradley B.1 (AUTHOR) bgilbert@ptcbio.com
Publikováno v:
Helvetica Chimica Acta. Sep2023, Vol. 106 Issue 9, p1-19. 19p.
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; December 1997, Vol. 283 Issue: 3 p1110-8, 9p
Publikováno v:
Chemischer Informationsdienst. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceafc8d1d803c6a62c5dffc19a33d3ca
https://doi.org/10.1002/chin.198035224
https://doi.org/10.1002/chin.198035224
Publikováno v:
Chemischer Informationsdienst. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1592d70ca01030e3e9f9cb606f3b2fa5
https://doi.org/10.1002/chin.198249238
https://doi.org/10.1002/chin.198249238
Autor:
H, Ramuz
Publikováno v:
Arzneimittel-Forschung. 28(11)
The alkylation of 2-(3,4-dimethoxyphenyl)-m-dithiane-1,1,3,3-tetraoxide (4) with N-(3-chloropropyl)-3,4-dimethoxy-N-methylphenethylamine (2) leads to N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)-N-methyl-m-dithiane-2-propylamine-1,1,3,3-tetraox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::602e2d61220113cf7a65fa344f987419
https://pubmed.ncbi.nlm.nih.gov/582903
https://pubmed.ncbi.nlm.nih.gov/582903