Zobrazeno 1 - 10
of 374
pro vyhledávání: '"H, Ponta"'
Autor:
M, Shatirishvili, A S, Burk, C M, Franz, G, Pace, T, Kastilan, K, Breuhahn, E, Hinterseer, A, Dierich, L, Bakiri, E F, Wagner, H, Ponta, T N, Hartmann, M, Tanaka, V, Orian-Rousseau
Publikováno v:
Cell Death & Disease
CD44, a large family of transmembrane glycoproteins, plays decisive roles in physiological and pathological conditions. CD44 isoforms are involved in several signaling pathways essential for life such as growth factor-induced signaling by EGF, HGF or
Autor:
I Preuss, Sophia Khaldoyanidi, P. Herrlich, Jonathan P. Sleeman, H. Ponta, J Moll, M Achtnich
Publikováno v:
Scopus-Elsevier
CD44 is important during myelopoiesis, although the contributions of variant CD44 proteins are unclear. We show here that in human long-term bone marrow culture antibodies recognizing a CD44 NH2-terminal epitope (mab 25-32) or a CD44v6 epitope (mab V
Publikováno v:
Gynecologic Oncology. 66:209-216
Variant proteins of the CD44 surface glycoprotein family are expressed on many different human tumors and their lymph node metastases. An epitope encoded by sequences of variant exons CD44v7 and v8 and recognized by the monoclonal antibody VFF17 is f
Autor:
Thomas Bauknecht, Peter Dall, Jürgen Moll, H. Ponta, Axel Göppinger, Peter Herrlich, Martin Hofmann, Armin Hekele, Albrecht Pfleiderer, Hans Ikenberg
Publikováno v:
International Journal of Cancer. 69:79-85
Splice variants of the cell surface glycoprotein CD44 (CD44v) have been implicated in the progression of various human tumors. In the present study, we have examined the expression pattern of a CD44v epitope encoded by the adjacent variant exons v7 a
Publikováno v:
The Journal of Immunology. 156:2085-2094
Splice variants of the glycoprotein CD44 (CD44v) that confer metastatic behavior to noninvasively growing rat tumor cells are transiently expressed on lymphocytes during activation. A mAb directed against an epitope encoded by CD44 exon v6 blocks bot
Publikováno v:
Trends in Glycoscience and Glycotechnology. 4:326-335
細胞表面分子探求への道筋が、機能の研究から出発して特定の分子を調べることになっても、またはある分子を知った上でその機能を調べることになっても、どちらにしても、基礎とな
Publikováno v:
Blood. 94(3)
The glycosaminoglycan hyaluronate (HA) is part of the extracellular environment in bone marrow. We show here that HA activates signal transduction cascades important for hemopoiesis. In myeloid and lymphoid long-term bone marrow cultures (LTBMC), tre
Autor:
J A, Foekens, P, Dall, J G, Klijn, P, Skroch-Angel, C J, Claassen, M P, Look, H, Ponta, W L, Van Putten, P, Herrlich, S C, Henzen-Logmans
Publikováno v:
International journal of cancer. 84(3)
CD44 is a family of cell surface transmembrane glycoproteins members which differ in the extracellular part by sequences derived by alternative splicing of 10 variant exons (v1-v10). CD44 proteins containing such variant sequences have been implicate
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 77(1)
Upon allogeneic transplantation (Tx) of pancreatic islets under the kidney capsule of diabetic rats, cells from draining lymph nodes and, to a minor degree, bone marrow transiently upregulate CD44 splice variants as detected by RT-PCR using CD44 vari
Publikováno v:
Cell. 95(5)