Zobrazeno 1 - 10
of 66
pro vyhledávání: '"H, Ogmundsdottir"'
Autor:
Francois Singh, Lea Wilhelm, Alan R. Prescott, Kevin Ostacolo, Jin-Feng Zhao, Margret H. Ogmundsdottir, Ian G. Ganley
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTPINK1, mutated in familial forms of Parkinson’s disease, initiates mitophagy following mitochondrial depolarization. However, it is difficult to monitor this pathway physiologically in mice as loss of PINK1 does not alter basal mitophagy le
Externí odkaz:
https://doaj.org/article/5b57ed0a9adb48e88193d7ed8114fd86
Autor:
Stephanie U. Greer, Jiamin Chen, Margret H. Ogmundsdottir, Carlos Ayala, Billy T. Lau, Richard Glenn C. Delacruz, Imelda T. Sandoval, Sigrun Kristjansdottir, David A. Jones, Derrick S. Haslem, Robin Romero, Gail Fulde, John M. Bell, Jon G. Jonasson, Eirikur Steingrimsson, Hanlee P. Ji, Lincoln D. Nadauld
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency results in increased oxidative stress, DNA damage and chronic cellular injury. Amo
Externí odkaz:
https://doaj.org/article/07556fe7ab554218a24d01d6e4b51299
Autor:
Óskar Ö. Hálfdánarson, Anton Pottegård, Einar S. Björnsson, Sigrún H. Lund, Margret H. Ogmundsdottir, Eiríkur Steingrímsson, Helga M. Ogmundsdottir, Helga Zoega
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 11 (2018)
Background: The use of proton-pump inhibitors (PPIs) has grown worldwide, and there are concerns about increased unsubstantiated long-term use. The aim of the study was to describe the real-world use of PPIs over the past decade in an entire national
Externí odkaz:
https://doaj.org/article/492983f3ced54bb0868c20240f7eb1ae
Autor:
B Sharad, M Magnusson, H Ogmundsdottir Michelsen, A Jujic, M Lidin, L Mellbin, N Shaat, J Wallert, E Hagstrom, M Leosdottir
Publikováno v:
European Heart Journal. 43
Background Patients with myocardial infarction (MI) have a high prevalence of diabetes mellitus (DM). Prognosis in patients with MI and DM is substantially worse than for those without DM. An unacceptably high proportion of patients with DM remain bo
Autor:
Margret H. Ogmundsdottir, Helga Zoega, Sigrun H. Lund, Helga M. Ögmundsdóttir, Anton Pottegård, Oskar Halfdanarson
Publikováno v:
Hálfdánarson, Ó, Pottegård, A, Lund, S H, Ogmundsdottir, M H, Ogmundsdottir, H M & Zoega, H 2020, ' Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancer ', Basic and Clinical Pharmacology and Toxicology, vol. 126, no. 6, pp. 484-491 . https://doi.org/10.1111/bcpt.13379
Proton pump inhibitors (PPIs) are commonly used drugs among cancer patients. Due to conflicting reports on their safety, we aimed to determine whether PPI use is associated with mortality among prostate cancer patients. In this population-based cohor
Autor:
Vivian Pogenberg, Margret H. Ogmundsdottir, Romana Schober, Morlin Milewski, Agnieszka Obarska-Kosinska, Rainer Schindl, Josué Ballesteros-Álvarez, Matthias Wilmanns, Ingibjörg Sigvaldadóttir, Eiríkur Steingrímsson
Publikováno v:
'Nucleic Acids Research ', vol: 48, pages: 934-948 (2020)
Nucleic Acids Research
Nucleic Acids Research
Interrupted dimeric coiled coil segments are found in a broad range of proteins and generally confer selective functional properties such as binding to specific ligands. However, there is only one documented case of a basic-helix–loop–helix leuci
Autor:
Stephanie U. Greer, Jiamin Chen, Margret H. Ogmundsdottir, Carlos Ayala, Billy T. Lau, Richard Glenn C. Delacruz, Imelda T. Sandoval, Sigrun Kristjansdottir, David A. Jones, Derrick S. Haslem, Robin Romero, Gail Fulde, John M. Bell, Jon G. Jonasson, Eirikur Steingrimsson, Hanlee P. Ji, Lincoln D. Nadauld
Publikováno v:
Scientific reports. 12(1)
Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency results in increased oxidative stress, DNA damage and chronic cellular injury. Among the co
Autor:
Mona Schlyter, H. Ogmundsdottir Michelsen, Maria Bäck, John Wallert, Margret Leosdottir, Anna Kiessling, Pontus Henriksson, I. Sjolin, M.J. Zaman, Alexandru Schiopu, Emil Hagström, E. Hag, Claes Held, Lennart Nilsson
Publikováno v:
European Heart Journal. 42
Background The benefits of specific cardiac rehabilitation (CR) programme components on patient outcomes after myocardial infarction (MI) remain unclear, as does their relative predictive strength compared to patient-level predictors. Purpose To iden
Autor:
Margret H. Ogmundsdottir, Andrea García-Llorca, Snaefridur Gudmundsdottir Aspelund, Thor Eysteinsson, Eiríkur Steingrímsson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Publisher's version (útgefin grein).
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Autor:
Eiríkur Steingrímsson, Oskar Halfdanarson, Margret H. Ogmundsdottir, Sigrun H. Lund, Helga Zoega, Helga M. Ögmundsdóttir, Katja Fall
Publikováno v:
Pharmacoepidemiology and Drug Safety. 28:471-478
Purpose Increased expression of Vacuolar-type H+ ATPases (V-ATPases), in the plasma membrane of cancer cells has been suggested to contribute to the development of aggressive cancer phenotypes by promoting acidic tumor microenvironments. Accumulating