Zobrazeno 1 - 10 of 625 pro vyhledávání: '"H, Northoff"'
1
Akademický článek
Exploring the expression and potential function of follicle stimulating hormone receptor in extragonadal cells related to abdominal aortic aneurysm.
Autor: V N Tedjawirja, A Mieremet, K B Rombouts, C Yap, A E Neele, B H Northoff, H J Chen, M Vos, D Klaver, K K Yeung, R Balm, V de Waard
Publikováno v: PLoS ONE, Vol 18, Iss 5, p e0285607 (2023)
IntroductionFollicle stimulating hormone (FSH) is identified to play a role in postmenopausal disease and hypothesized to affect abdominal aortic aneurysm (AAA) onset/progression in postmenopausal women. We aimed to detect FSHR gene expression in AAA
Externí odkaz: https://doaj.org/article/466e8f7603b842c39a655060b077bf9a
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2
Akademický článek
Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression
Autor: Gabor Gäbel, Bernd H. Northoff, Amanda Balboa, Mediha Becirovic‐ Agic, Marcelo Petri, Albert Busch, Lars Maegdefessel, Adrian Mahlmann, Stefan Ludwig, Daniel Teupser, Vivian de Waard, Jonathan Golledge, Anders Wanhainen, Dick Wågsäter, Lesca M. Holdt, Jan H. N. Lindeman
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 17 (2021)
Background While numerous interventions effectively interfered with abdominal aortic aneurysm (AAA) formation/progression in preclinical models, none of the successes translated into clinical success. Hence, a systematic exploration of parallel and d
Externí odkaz: https://doaj.org/article/c5e429062f6d429b954ba264ac7628c9
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3
Akademický článek
Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
Autor: Lesca M. Holdt, Anika Stahringer, Kristina Sass, Garwin Pichler, Nils A. Kulak, Wolfgang Wilfert, Alexander Kohlmaier, Andreas Herbst, Bernd H. Northoff, Alexandros Nicolaou, Gabor Gäbel, Frank Beutner, Markus Scholz, Joachim Thiery, Kiran Musunuru, Knut Krohn, Matthias Mann, Daniel Teupser
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Circular RNAs are widely expressed in eukaryotic cells but their functions and mechanisms of action are still being elucidated. Here the authors show that circANRILmodulates rRNA maturation and confers protection again atherosclerosis.
Externí odkaz: https://doaj.org/article/151d6b7d2525435dacde77b53d5d85b1
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4
Akademický článek
Molecular Fingerprint for Terminal Abdominal Aortic Aneurysm Disease
Autor: Gabor Gäbel, Bernd H. Northoff, Irina Weinzierl, Stefan Ludwig, Irene Hinterseher, Wolfgang Wilfert, Daniel Teupser, Stefan A. Doderer, Hendrik Bergert, Frank Schönleben, Jan H. N. Lindeman, Lesca M. Holdt
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 12 (2017)
BackgroundClinical decision making in abdominal aortic aneurysms (AAA) relies completely on diameter. At this point, improved decision tools remain an unmet medical need. Our goal was to identify changes at the molecular level specifically leading up
Externí odkaz: https://doaj.org/article/85d16c11dc8c4e9cbc17c12c2c5b1c9d
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5
Differential expression of gut miRNAs in idiopathic Parkinson's disease
Autor: Rohit Kumar, Kai Bötzel, Anna Kurz, Rainer Hübner, Verena E. Rozanski, Sainitin Donakonda, Günter U. Höglinger, Bernd H. Northoff, Jörg Schirra, Johannes Schwarz, Thomas Koeglsperger, Catharina Wenk, Lesca M. Holdt
Publikováno v: Parkinsonism & related disorders 88, 46-50 (2021). doi:10.1016/j.parkreldis.2021.05.022
Objective In the present work, we aimed to investigate the expression of microRNAs (miRNAs) in routine colonic biopsies obtained from patients with idiopathic Parkinson's disease (PD) and to address their value as a diagnostic biomarker for PD and th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44002f0025d18b54159c24fe04d850fe
https://doi.org/10.1016/j.parkreldis.2021.05.022
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6
Akademický článek
Whole genome sequencing of Brucella melitensis isolated from 57 patients in Germany reveals high diversity in strains from Middle East.
Autor: Enrico Georgi, Mathias C Walter, Marie-Theres Pfalzgraf, Bernd H Northoff, Lesca M Holdt, Holger C Scholz, Lothar Zoeller, Sabine Zange, Markus H Antwerpen
Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0175425 (2017)
Brucellosis, a worldwide common bacterial zoonotic disease, has become quite rare in Northern and Western Europe. However, since 2014 a significant increase of imported infections caused by Brucella (B.) melitensis has been noticed in Germany. Patien
Externí odkaz: https://doaj.org/article/c62219bcab784f64873076dc689aaaf0
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7
Parallel murine and human aortic wall genomics reveals metabolic reprogramming as key driver of abdominal aortic aneurysm progression
Autor: Lesca M. Holdt, Lars Maegdefessel, Stefan Ludwig, Albert Busch, Adrian Mahlmann, Dick Wågsäter, Jonathan Golledge, Jan H.N. Lindeman, Bernd H. Northoff, Daniel Teupser, Amanda Balboa, Gabor Gäbel, Anders Wanhainen, Vivian de Waard, Mediha Becirovic-Agic, Marcelo Heron Petri
Publikováno v: Journal of the American Heart Association, 10(17):e020231. Wiley-Blackwell
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 17 (2021)
Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 10(17). WILEY
Background While numerous interventions effectively interfered with abdominal aortic aneurysm (AAA) formation/progression in preclinical models, none of the successes translated into clinical success. Hence, a systematic exploration of parallel and d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e6c87c710c98695e8c89ca62777805
https://pure.amc.nl/en/publications/parallel-murine-and-human-aortic-wall-genomics-reveals-metabolic-reprogramming-as-key-driver-of-abdominal-aortic-aneurysm-progression(6566d7f7-456a-4f2c-bcf4-95537322c3c3).html
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9
Antibody response to mRNA SARS-CoV-2 vaccines in haemodialysis patients
Autor: Sandra E. Hasmann, Michael Paal, Ulf Schönermarck, Wilke Beuthien, Tobias Lau, Michael Fischereder, Gero von Gersdorff, Daniel Teupser, Norbert Thaller, Florian M Arend, Julia Krappe, Johanna Sorodoc-Otto, Marcell Toepfer, Daniela Soreth-Rieke, Bernd H. Northoff, Simon Rau, Mathias Bruegel
Publikováno v: Clinical Kidney Journal
BackgroundSome studies have shown an attenuated immune response in haemodialysis patients after vaccination. The present study examines the humoral response after mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5c33b57c0e67372e1c14680582ccf4
https://pubmed.ncbi.nlm.nih.gov/34603700
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10
Comparative Routine Therapeutic Drug Monitoring of Mycophenolic Acid in human Plasma with HPLC-UV and Isotope Dilution LC-MS/MS
Autor: Michael Vogeser, Bernd H. Northoff, Katharina Habler, Michael Paal
Publikováno v: Clinical laboratory. 66(4)
Background Therapeutic drug monitoring (TDM) of the immunosuppressant mycophenolic acid (MPA) is especially recommended for the control of personalized immunosuppressive therapy. Various test systems are available for MPA monitoring, including high p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e9517f5f497e1161a4192f8bdbd1ca
https://pubmed.ncbi.nlm.nih.gov/32255280
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