A. H. Musgrove, M.R.C.S., L.R.C.P., D.A., F.F.A. R.C.S.

Publikováno v: The British Medical Journal, 1966 May 01. 1(5496), 1176-1177.

Externí odkaz: https://www.jstor.org/stable/25407742

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The contribution of VEGF signalling to fostamatinib-induced blood pressure elevation

Autor: M, Skinner, K, Philp, D, Lengel, L, Coverley, E, Lamm Bergström, P, Glaves, H, Musgrove, H, Prior, M, Braddock, R, Huby, J O, Curwen, P, Duffy, A R, Harmer

Publikováno v: British journal of pharmacology. 171(9)

Fostamatinib is an inhibitor of spleen tyrosine kinase (TK). In patients, fostamatinib treatment was associated with increased BP. Some TK inhibitors cause BP elevation, by inhibiting the VEGF receptor 2 (VEGFR2). Here, we have assessed the mechanist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::345b7c7c3e3da8cd0c0365f4e66135be
https://pubmed.ncbi.nlm.nih.gov/24329544

Fundamental Neurochemistry Review: At the intersection between the brain and the immune system: Non-coding RNAs spanning learning, memory and adaptive immunity.

Autor: Musgrove MRB; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., Mikhaylova M; AG Optobiologie, Institute für Biologie, Humboldt Universität zu Berlin, Berlin, Germany., Bredy TW; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.

Publikováno v: Journal of neurochemistry [J Neurochem] 2024 Jun; Vol. 168 (6), pp. 961-976. Date of Electronic Publication: 2024 Feb 09.

Comparison of plasma and tissue levels of ZD1694 (Tomudex), a highly polyglutamatable quinazoline thymidylate synthase inhibitor, in preclinical models

Autor: F Sutcliffe, Ann L. Jackman, G.W. Aherne, H Musgrove, N Lawrence, E Ward, D Dobinson, T C Stephens, Stephen Clarke

Publikováno v: British Journal of Cancer

ZD1694 (Tomudex, raltitrexed) is a specific quinazoline antifolate thymidylate synthase inhibitor that relies on polyglutamation for high potency. Antibodies to ZD1694 have been used to establish a sensitive radioimmunoassay as an alternative to high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8497e21892ac5aaf9cbf611d276c67fd
https://pubmed.ncbi.nlm.nih.gov/9460992