Zobrazeno 1 - 10
of 1 166
pro vyhledávání: '"H, Man"'
Autor:
R. Sumanth Iyer, Sarah R. Needham, Ioannis Galdadas, Benjamin M. Davis, Selene K. Roberts, Rico C. H. Man, Laura C. Zanetti-Domingues, David T. Clarke, Gilbert O. Fruhwirth, Peter J. Parker, Daniel J. Rolfe, Francesco L. Gervasio, Marisa L. Martin-Fernandez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The Epidermal Growth Factor Receptor (EGFR) is frequently found to be mutated in non-small cell lung cancer. Oncogenic EGFR has been successfully targeted by tyrosine kinase inhibitors, but acquired drug resistance eventually overcomes the e
Externí odkaz:
https://doaj.org/article/85aaaaecf9114b44adb21e316e7276e8
Autor:
Yongqi Huang, Jitao Wen, Lisa-Marie Ramirez, Eymen Gümüşdil, Pravin Pokhrel, Viet H. Man, Haiqiong Ye, Yue Han, Yunfei Liu, Ping Li, Zhengding Su, Junmei Wang, Hanbin Mao, Markus Zweckstetter, Sarah Perrett, Si Wu, Meng Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Preventing tau aggregation is a potential therapeutic strategy in Alzheimer’s disease and other tauopathies. Recently, liquid–liquid phase separation has been found to facilitate the formation of pathogenic tau conformations and fibrilla
Externí odkaz:
https://doaj.org/article/f29b0f1178684b23b9c392b3ba2dbc9b
Autor:
Akash Mavilakandy, Ivelin Koev, Bharat Sidhu, Ahmed Kotb, Ibrahim Antoun, Sharon H Man, Zakariyya Vali, Vivetha Pooranachandran, Joseph Barker, Gaurav Panchal, Xin Li, G. André Ng
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 7, p 250 (2024)
Background: Pulmonary vein isolation (PVI) ablation is the established gold standard therapy for patients with symptomatic drug refractory atrial fibrillation (AF). Advancements in radiofrequency (RF) ablation, have led to the development of the nove
Externí odkaz:
https://doaj.org/article/a87e45871c6646c8814acafd103f5f97
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Photosensitive opsins detect light and perform image- or nonimage-forming tasks. Opsins such as the “classical” visual opsins and melanopsin are well studied. However, the retinal expression and functions of a novel family of neuropsins are poorl
Externí odkaz:
https://doaj.org/article/bfc4d00d14384d70adfbc0cf3a97a533
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4611-4619 (2020)
Externí odkaz:
https://doaj.org/article/42dd42a02312406ab6a8c559b3704956
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2022)
The eye, the pineal complex and the skin are important photosensitive organs. The African clawed frog, Xenopus laevis, senses light from the environment and adjusts skin color accordingly. For example, light reflected from the surface induces camoufl
Externí odkaz:
https://doaj.org/article/773aa31aaf734563a963867900458af7
Publikováno v:
Atmospheric Chemistry and Physics, Vol 19, Pp 4899-4916 (2019)
Since 1 January 2017, ships berthed at the core ports of three designated “domestic emission control areas” (DECAs) in China should be using fuel with a sulfur content less than or equal to 0.5 %. In order to evaluate the impacts of fuel switch
Externí odkaz:
https://doaj.org/article/7d163370dfc748a78a6e180c1b79c7b6
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 9527-9545 (2018)
Emissions from ships at berth play an important role regarding the exposure of high density human populations to atmospheric pollutants in port areas; however, these emissions are not well understood. In this study, volatile organic compounds (VOC
Externí odkaz:
https://doaj.org/article/a12d044ed7f24c7cb840b39158d1dfb5
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 4, Iss 2, Pp 76-79 (2018)
We report the case of a 44-year-old woman who developed an acute type B aortic dissection caused by an entry tear from an aneurysmal left common iliac artery that extended retrograde to the proximal descending thoracic aorta. She experienced refracto
Externí odkaz:
https://doaj.org/article/a645edd0815146b98dbf2435d20824f6
Autor:
Zitong Shao, Waiting Tai, Yingshan Qiu, Rico C. H. Man, Qiuying Liao, Michael Y. T. Chow, Philip C. L. Kwok, Jenny K. W. Lam
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2044 (2021)
Multi-drug-resistant tuberculosis (MDR-TB) is a huge public health problem. The treatment regimen of MDR-TB requires prolonged chemotherapy with multiple drugs including second-line anti-TB agents associated with severe adverse effects. Capreomycin,
Externí odkaz:
https://doaj.org/article/7acc961ce28e4a4096146d3d5c9bb907