Zobrazeno 1 - 10
of 84
pro vyhledávání: '"H, Lüss"'
Autor:
J, Knapp, P, Bokník, B, Linck, H, Lüss, F U, Müller, P, Nacke, J, Neumann, U, Vahlensieck, W, Schmitz
Publikováno v:
British Journal of Pharmacology. 120:421-428
1. Cantharidin, an inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), increased basal tone of bovine isolated coronary artery rings (CARs) with and without endothelium in a time- and concentration-dependent manner with pEC50 values of abou
Publikováno v:
L’insuffisance cardiaque aiguë ISBN: 9782287340659
Les hormones peptidiques, qui appartiennent a la famille des peptides natriuretiques (NP), jouent un role important dans le maintien de la fonction cardiaque et renale en regulant le volume hydrique, la pression arterielle et la concentration en sodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2870609501be41d54e01a8f8deb721e
https://doi.org/10.1007/978-2-287-34066-6_16
https://doi.org/10.1007/978-2-287-34066-6_16
Autor:
B, Linck, P, Boknik, J, Knapp, K, Kikuchi, H, Lüss, F U, Müller, K, Nomoto, J, Neumann, W, Schmitz
Publikováno v:
Molecular and cellular biochemistry. 223(1-2)
The aim of this study was to investigate the functional properties of the promoter of the protein phosphatase 1alpha catalytic subunit. Luciferase plasmids with different fragments of the rat catalytic subunit of the protein phosphatase 1alpha promot
Autor:
B, Linck, P, Bokník, S, Huke, U, Kirchhefer, J, Knapp, H, Lüss, F U, Müller, J, Neumann, Z, Tanriseven, U, Vahlensieck, H A, Baba, L R, Jones, K D, Philipson, W, Schmitz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Overexpression of calsequestrin (CSQ) induces severe cardiac hypertrophy, whereas overexpression of Na(+)-Ca(2+) exchanger (NCX) does not affect cardiac weight. To investigate a possible beneficial effect of NCX in hypertrophy, we produced transgenic
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
In this study we characterized the effects of the protein phosphatase (PP) type 1 and type 2A inhibitor cantharidin (Cant) and its structural analogs cantharidic acid and endothall on PP activity, force of contraction, and myosin light chain phosphor
Autor:
J, Neumann, U, Vahlensieck, P, Boknik, B, Linck, H, Lüss, F U, Müller, G P, Matherne, W, Schmitz
Publikováno v:
British journal of pharmacology. 128(7)
1. Adenosine and the A1-adenosine receptor agonist R-PIA, exerted a negative inotropic effect in isolated, electrically driven left atria of wild-type mice. 2. In left atria of mice overexpressing the A1-adenosine receptor, adenosine and R-PIA exerte
Autor:
J, Knapp, P, Bokník, I, Lüss, S, Huke, B, Linck, H, Lüss, F U, Müller, T, Müller, P, Nacke, T, Noll, H M, Piper, W, Schmitz, U, Vahlensieck, J, Neumann
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(3)
In this study, we characterized the effects of the protein phosphatases type 1 (PP 1) and type 2A (PP 2A) inhibitor cantharidin in endothelial cells. We identified catalytic subunits of PP 1alpha, PP 2Aalpha, and PP 2Abeta immunologically in bovine a
Autor:
H, Fischer, J C, Becker, P, Boknik, V, Huber, H, Lüss, J, Neumann, W, Schmitz, W, Domschke, J W, Konturek
Publikováno v:
Alimentary pharmacologytherapeutics. 13(4)
Gastric adaptation to aspirin is well-documented. However, the mechanisms underlying the reduction of aspirin-induced mucosal damage despite continued ingestion of the drug remain poorly understood.Eight healthy volunteers who received aspirin 1 g b.
Publikováno v:
Cardiovascular research. 37(3)
Myocardial hibernation and stunning are characterised by a reversible contractile dysfunction during and after ischaemia, respectively. Calcium homeostasis might be disturbed in hibernation and stunning due to altered expression of cardiac proteins i
Autor:
J, Knapp, P, Bokník, S, Huke, H, Lüss, F U, Müller, T, Müller, P, Nacke, W, Schmitz, U, Vahlensieck, J, Neumann
Publikováno v:
British journal of pharmacology. 123(5)
1. The aim of this study was to investigate the mechanism(s) of the vasoconstrictor effect of cantharidin in bovine preparations. 2. Catalytic subunits of protein phosphatase type 1 (PP 1) and type 2A (PP 2A) were immunologically identified in corona