Inhibitors of the renin-angiotensin system ameliorates clinical and pathological aspects of experimentally induced nephrotoxic serum nephritis

Autor: M. E. Ougaard, H. E. Jensen, I. D. Thuen, E. G. Petersen, P. H. Kvist

Publikováno v: Renal Failure, Vol 40, Iss 1, Pp 640-648 (2018)

Introduction: Chronic kidney disease (CKD) is a global health concern, but the current treatments only slow down the progression. Thus an improved understanding of the pathogenesis and novel treatments of CKD are needed. The nephrotoxic nephritis (NT

Externí odkaz: https://doaj.org/article/701acb5708c44b139971b36d0df7cd86

Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model

Autor: Josué Castro-Mejía, Maja Jakesevic, Łukasz Krych, Dennis S. Nielsen, Lars H. Hansen, Bodil C. Sondergaard, Peter H. Kvist, Axel K. Hansen, Thomas L. Holm

Publikováno v: Gastroenterology Research and Practice, Vol 2016 (2016)

Background and Aim. Crohn’s disease is associated with gut microbiota (GM) dysbiosis. Treatment with the anti-IL-12p40 monoclonal antibody (12p40-mAb) has therapeutic effect in Crohn’s disease patients. This study addresses whether a 12p40-mAb tr

Externí odkaz: https://doaj.org/article/fb6f359e86ac4ef189daf717302497dc

Factor XIII Transglutaminase Supports the Resolution of Mucosal Damage in Experimental Colitis.

Autor: Christina Andersson, Peter H Kvist, Kathryn McElhinney, Richard Baylis, Luise K Gram, Hermann Pelzer, Brian Lauritzen, Thomas L Holm, Simon Hogan, David Wu, Brian Turpin, Whitney Miller, Joseph S Palumbo

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128113 (2015)

The thrombin-activated transglutaminase factor XIII (FXIII) that covalently crosslinks and stablizes provisional fibrin matrices is also thought to support endothelial and epithelial barrier function and to control inflammatory processes. Here, gene-

Externí odkaz: https://doaj.org/article/f7fe539e40104b7b993051be90c862e4

Ear-to-Ear Propagation Model based on Geometrical Theory of Diffraction

Autor: Nikolaj P. B. Kammersgaard, Soren H. Kvist, Kaj Bjarne Jakobsen, Jesper Thaysen

Publikováno v: Kammersgaard, N P B, Kvist, S H, Thaysen, J & Jakobsen, K B 2019, ' Ear-to-Ear Propagation Model based on Geometrical Theory of Diffraction ', IEEE Transactions on Antennas and Propagation, vol. 67, no. 2, pp. 1153-1160 . https://doi.org/10.1109/TAP.2018.2882587

An ear-to-ear propagation model based on geometrical theory of diffraction is presented. The model uses the creeping wave loss along the geodesic paths that connect the ears. It is the first model to investigate which geodesic paths that link the ear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1d26244afc84f0141f7b03bdda8d39
https://orbit.dtu.dk/en/publications/85256e02-f197-4bb8-8026-29d384559bf8

Depletion of regulatory T cells in a hapten-induced inflammation model results in prolonged and increased inflammation driven by T cells

Autor: Anne D. Christensen, P. H. Kvist, Søren Skov, Claus Haase

Publikováno v: Clinical and Experimental Immunology. 179:485-499

Summary Regulatory T cells (Tregs) are known to play an immunosuppressive role in the response of contact hypersensitivity (CHS), but neither the dynamics of Tregs during the CHS response nor the exaggerated inflammatory response after depletion of T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cad34ecee4fe2b4ec61306f33c3bef
https://doi.org/10.1111/cei.12466