Zobrazeno 1 - 10
of 481
pro vyhledávání: '"H, Kimball"'
Autor:
Yang Cao, Laurent Vergnes, Yu-Chen Wang, Calvin Pan, Karthickeyan Chella Krishnan, Timothy M. Moore, Manuel Rosa-Garrido, Todd H. Kimball, Zhiqiang Zhou, Sarada Charugundla, Christoph D. Rau, Marcus M. Seldin, Jessica Wang, Yibin Wang, Thomas M. Vondriska, Karen Reue, Aldons J. Lusis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this paper, the authors show that sex differences in mitochondrial DNA levels and function in the heart contribute to sex biases in functions relevant to heart failure, identifying Acsl6 as a mitochondrial sex-biased regulator of diastolic functio
Externí odkaz:
https://doaj.org/article/89de6b77175046a88778990393d83932
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The voltage-gated sodium (NaV) channel subtype NaV1.7 plays a critical role in pain signaling, making it an important drug target. Here we studied the molecular interactions between μ-Conotoxin KIIIA (KIIIA) and the human NaV1.7 channel (hNaV1.7). W
Externí odkaz:
https://doaj.org/article/06d58ebefa964da4b71c735ad3867fad
Autor:
Ayman El-Mohandes, Trenton M. White, Katarzyna Wyka, Lauren Rauh, Kenneth Rabin, Spencer H. Kimball, Scott C. Ratzan, Jeffrey V. Lazarus
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract This study assesses attitudes towards COVID-19 vaccination and the predictive value of COVID-VAC, a novel scale, among adults in the four largest US metropolitan areas and nationally. A 36-item survey of 6037 Americans was conducted in mid-A
Externí odkaz:
https://doaj.org/article/fc2e06fe92de4c5d90bf0d2d185b2a27
Autor:
Matthew A. Fischer, Aman Mahajan, Maximilian Cabaj, Todd H. Kimball, Marco Morselli, Elizabeth Soehalim, Douglas J. Chapski, Dennis Montoya, Colin P. Farrell, Jennifer Scovotti, Claudia T. Bueno, Naomi A. Mimila, Richard J. Shemin, David Elashoff, Matteo Pellegrini, Emma Monte, Thomas M. Vondriska
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and post-operative atrial fibrillation (POAF) is a major healthcare burden, contributing to an increased risk of stroke, kidney failure, heart attack and death. Geneti
Externí odkaz:
https://doaj.org/article/d7d7b22b25d5424c99cc55fb3dc5f4de
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Misophonia is a condition characterized by hypersensitivity and strong emotional reactivity to specific auditory stimuli. Misophonia clinical presentations are relatively complex and reflect individualized experiences across clinical populations. Lik
Externí odkaz:
https://doaj.org/article/e2e2eff42e624310a72abe5e27f509e8
Akademický článek
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Publikováno v:
Frontiers in Pharmacology. 14
The voltage-gated sodium (Nav) channel subtype Nav1.7 plays a critical role in pain signaling, making it an important drug target. A number of peptide toxins from cone snails (conotoxins) bind to the extracellular vestibule of the Nav channel pore an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc84b4ec1983d1bfd588b98accb7440
https://doi.org/10.3389/fphar.2023.1156855
https://doi.org/10.3389/fphar.2023.1156855
Autor:
Shuaishuai Hu, Douglas J. Chapski, Natalie Gehred, Todd H. Kimball, Tatiana Gromova, Angelina Flores, Amy C. Rowat, Junjie Chen, René R. Sevag Packard, Emily Olszewski, Jennifer Davis, Christoph D. Rau, Timothy A. McKinsey, Manuel Rosa Garrido, Thomas M. Vondriska
SummaryTuning of genome structure and function is accomplished by chromatin binding proteins, which determine the transcriptome and phenotype of the cell. We sought to investigate how communication between extracellular stress and chromatin structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1363c83902002223822dc37e46b5d9f8
https://doi.org/10.1101/2022.11.29.518399
https://doi.org/10.1101/2022.11.29.518399
Akademický článek
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