Zobrazeno 1 - 10
of 954
pro vyhledávání: '"H, Hudson"'
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Rapid and accurate pathogen identification is required for disease management. Compared to sequencing entire genomes, targeted sequencing may be used to direct sequencing resources to genes of interest for microbe identification a
Externí odkaz:
https://doaj.org/article/391a717a5331472da97583ce16aa86fa
Autor:
Satomi Ando, Charles M. Perkins, Yamato Sajiki, Chase Chastain, Rajesh M. Valanparambil, Andreas Wieland, William H. Hudson, Masao Hashimoto, Suresh S. Ramalingam, Gordon J. Freeman, Rafi Ahmed, Koichi Araki
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
T cell exhaustion is a state of T cell dysfunction associated with expression of programmed death 1 (PD-1). Exhausted CD8+ T cells are maintained by self-renewing stem-like T cells that provide differentiated TIM3+ cells, a part of which possesses ef
Externí odkaz:
https://doaj.org/article/dfaca50a88f74b02a4c1d34e9ba0a73c
Autor:
William H. Hudson, Lisa J. Sudmeier
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101391- (2022)
Summary: We present a protocol to localize T cell receptor clones using the Visium spatial transcriptomics platform. This approach permits simultaneous localization of both gene expression and T cell clonotypes in situ within tissue sections. T cell
Externí odkaz:
https://doaj.org/article/1f41a82eb6c24a44b97c700ef24a1aec
Autor:
William H. Hudson, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Donald J. McGuire, Rafi Ahmed, Haydn T. Kissick
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show tha
Externí odkaz:
https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd
Autor:
Mehul S. Suthar, Matthew G. Zimmerman, Robert C. Kauffman, Grace Mantus, Susanne L. Linderman, William H. Hudson, Abigail Vanderheiden, Lindsay Nyhoff, Carl W. Davis, Oluwaseyi Adekunle, Maurizio Affer, Melanie Sherman, Stacian Reynolds, Hans P. Verkerke, David N. Alter, Jeannette Guarner, Janetta Bryksin, Michael C. Horwath, Connie M. Arthur, Natia Saakadze, Geoffrey H. Smith, Srilatha Edupuganti, Erin M. Scherer, Kieffer Hellmeister, Andrew Cheng, Juliet A. Morales, Andrew S. Neish, Sean R. Stowell, Filipp Frank, Eric Ortlund, Evan J. Anderson, Vineet D. Menachery, Nadine Rouphael, Aneesh K. Mehta, David S. Stephens, Rafi Ahmed, John D. Roback, Jens Wrammert
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100040- (2020)
Summary: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection
Externí odkaz:
https://doaj.org/article/5f530d0f4bbd408ebb78b8346f2ddc5f
Autor:
William H. Hudson, Ian Mitchelle S. de Vera, Jerome C. Nwachukwu, Emily R. Weikum, Austin G. Herbst, Qin Yang, David L. Bain, Kendall W. Nettles, Douglas J. Kojetin, Eric A. Ortlund
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Glucocorticoid receptor (GR) regulates immunity and inflammation but the mechanisms by which GR represses proinflammatory genes are still being debated. Here the authors use a multidisciplinary approach and show that GR binds to a cryptic site within
Externí odkaz:
https://doaj.org/article/4e26ab6d87a84291886bf3c3f88bfcfb
Autor:
Jaclyn M. Camuglia, Torrey R. Mandigo, Richard Moschella, Jenna Mark, Christine H. Hudson, Derek Sheen, Eric S. Folker
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Background A strength of Drosophila as a model system is its utility as a tool to screen for novel regulators of various functional and developmental processes. However, the utility of Drosophila as a screening tool is dependent on the speed
Externí odkaz:
https://doaj.org/article/ea00455abbad4f00b3885d54b237498d
Autor:
Masao Hashimoto, Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn T. Kissick, William H. Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland, Judong Lee, Daniel T. McManus, James L. Ross, Se Jin Im, Junghwa Lee, Jian-Xin Lin, Bin Hu, Erin E. West, Christopher D. Scharer, Gordon J. Freeman, Arlene H. Sharpe, Suresh S. Ramalingam, Alex Pellerin, Volker Teichgräber, William J. Greenleaf, Christian Klein, Jorg J. Goronzy, Pablo Umaña, Warren J. Leonard, Kendall A. Smith, Rafi Ahmed
Publikováno v:
Nature. 610:173-181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7851039a7e457c18b997947061dde5ce
https://doi.org/10.1038/s41586-022-05257-0
https://doi.org/10.1038/s41586-022-05257-0
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