Zobrazeno 1 - 10
of 660
pro vyhledávání: '"H, Holmsen"'
Autor:
H. Holmsen
Publikováno v:
Acta Medica Scandinavica. 191:169-172
Autor:
H. Holmsen, M.C. Rozenberg
Publikováno v:
Acta Medica Scandinavica. 191:113-116
Publikováno v:
Journal of Biochemical and Biophysical Methods. 35:185-195
A polarographic method for measuring the concentration of authentic nitric oxide (NO) in aqueous solutions is described. When solutions of NO were injected into aqueous solutions containing dissolved oxygen, NO reacted with oxygen to give nitrite. Th
Publikováno v:
Journal of Biological Chemistry. 269:13874-13879
Human platelets contain platelet-derived growth factor (PDGF) in their alpha-granules which is released during platelet exocytosis. We show by immunoprecipitation and 125I-PDGF binding experiments that human platelets have functionally active PDGF al
Autor:
H. Holmsen
Publikováno v:
European Journal of Clinical Investigation. 24:3-8
Platelets respond through discrete receptors to a number of physiological agonists and foreign surfaces with a sequence of measurable responses: shape change, aggregation, secretion and arachidonate liberation. Three secretory responses are distingui
Publikováno v:
Journal of Biological Chemistry. 267:15635-15641
The aminoglycoside neomycin has recently been found to affect certain platelet-derived growth factor (PDGF) responses in C3H/10T1/2 C18 fibroblasts. Using porcine aortic endothelial cells transfected with PDGF alpha- or beta-receptors, we explored th
Publikováno v:
European Surgical Research. 23:45-50
The platelets play an important role in the normal hemostasis, and it is known that both natural and synthetic macromolecules may induce platelet activation and aggregation. Thus, the purpose of the present study was to investigate the platelet aggre
Autor:
M A, Crawford, M, Bloom, S, Cunnane, H, Holmsen, K, Ghebremeskel, J, Parkington, W, Schmidt, A J, Sinclair, C L, Broadhurst
Publikováno v:
World review of nutrition and dietetics. 88
Publikováno v:
The Biochemical journal.
Human platelets release platelet-derived growth factor (PDGF) from alpha-granules during platelet activation. We have previously shown that platelets have PDGF alpha-receptors, a transmembrane tyrosine kinase that takes part in negative feedback regu
Publikováno v:
The Journal of biological chemistry. 275(10)
sn-1,2-diacylglycerol (DAG), a key intermediate in lipid metabolism, activates protein kinase C and is a fusogen. Phosphoinositides, the main sources of DAG in cell signaling, contain mostly stearoyl and arachidonoyl in the sn-1 and -2 positions, res