Zobrazeno 1 - 10
of 416
pro vyhledávání: '"H, Farah"'
Autor:
Mohamed H. Farah, Christine í Dali, Samuel Groeschel, Mihai Moldovan, David A. H. Whiteman, C. J. Malanga, Ingeborg Krägeloh‐Mann, Jing Li, Norman Barton, Christian Krarup
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 328-341 (2024)
Abstract Objective To evaluate the longitudinal correlations between sulfatide/lysosulfatide levels and central and peripheral nervous system function in children with metachromatic leukodystrophy (MLD) and to explore the impact of intravenous recomb
Externí odkaz:
https://doaj.org/article/2da5ca1a176140d28b9f49563ce77f78
Autor:
Yu Su, Meixiang Huang, Ajit G. Thomas, John Maragakis, Kaitlyn D. J. Huizar, Yuxin Zheng, Ying Wu, Mohamed H. Farah, Barbara S. Slusher
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6893 (2024)
Peripheral nerve injuries (PNIs) represent a significant clinical challenge, particularly in elderly populations where axonal remyelination and regeneration are impaired. Developing therapies to enhance these processes is crucial for improving PNI re
Externí odkaz:
https://doaj.org/article/63e167e0e09840b78ab84117d6cb590d
Autor:
Katherine L. Marshall, Labchan Rajbhandari, Arun Venkatesan, Nicholas J. Maragakis, Mohamed H. Farah
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by degeneration of upper and lower motor neurons that leads to muscle weakness, paralysis, and death, but the effects of disease-causing mutations
Externí odkaz:
https://doaj.org/article/618425bc3da44c26b14ec76b7174e164
Autor:
John A. Fissel, Mohamed H. Farah
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Following peripheral nerve injury, multiple cell types, including axons, Schwann cells, and macrophages, coordinate to promote nerve regeneration. However, this capacity for repair is limited, particularly in older populations, and current t
Externí odkaz:
https://doaj.org/article/4347734a737347ae80df0caca0373444
Autor:
Katherine L Marshall, Mohamed H Farah
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 10, Pp 1901-1910 (2021)
Nervous system disorders are prevalent health issues that will only continue to increase in frequency as the population ages. Dying-back axonopathy is a hallmark of many neurologic diseases and leads to axonal disconnection from their targets, which
Externí odkaz:
https://doaj.org/article/17bac7f01d744405be0aa92a5b62a1a5
Autor:
Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108610- (2021)
Summary: Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axon
Externí odkaz:
https://doaj.org/article/3365b3bdc34a429095f1971a8c5318cd
Publikováno v:
Heliyon, Vol 5, Iss 12, Pp e02682- (2019)
Chikungunya virus (CHIKV) is maintained in the sylvatic cycle in West Africa and is transmitted by Aedes mosquito species to monkeys. In 2006, four verified CHIKV isolates were obtained during a survey of arboviruses in monkeys (Macaca fascicularis)
Externí odkaz:
https://doaj.org/article/30e4d20de408499098bfd006267741cd
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 147-157 (2017)
Axons of the peripheral nervous system possess the capacity to regenerate following injury. Previously, we showed that genetically knocking out Beta-Site APP-Cleaving Enzyme 1 (BACE1) leads to increased nerve regeneration. Two cellular components, ma
Externí odkaz:
https://doaj.org/article/cd48b7794f9547b99e34370609912fbe
Autor:
Carolyn Tallon, Mohamed H Farah
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 10, Pp 1565-1574 (2017)
While the peripheral nervous system has the capacity to regenerate following a nerve injury, it is often at a slow rate and results in unsatisfactory recovery, leaving patients with reduced function. Many regeneration associated genes have been ident
Externí odkaz:
https://doaj.org/article/0bc36e55ce2d43689b5f7f6003da7ca5
Autor:
B.T. Kuhn, A. Veale, H. Farah, R. Mahadeva, C.L. Chang, C.D. Brown, M.A. Campos, J. Lascano, S. Bhagwat, T. Boyea, E. Babcock, C. Veldstra, V. Andrianov, J. Kalabus, B. Eckelman, M.L. Brantly
Publikováno v:
C15. EMERGING COPD DIAGNOSTICS AND TREATMENTS.